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MAPK14 [secretory granule lumen]
Stable Identifier
R-HSA-6803300
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
MAP kinase p38 alpha, Mitogen-activated protein kinase 14, MK14_HUMAN, p38 alpha
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
MAPK14 [secretory granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q16539 MAPK14
Gene Names
MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
Chain
initiator methionine:1, chain:2-360
Reference Genes
BioGPS Gene:1432 MAPK14
COSMIC (genes):MAPK14 MAPK14
CTD Gene:1432 MAPK14
dbSNP Gene:1432 MAPK14
ENSEMBL:ENSG00000112062 MAPK14
HGNC:6876 MAPK14
KEGG Gene (Homo sapiens):1432 MAPK14
Monarch:1432 MAPK14
NCBI Gene:1432 MAPK14
OMIM:600289 MAPK14
UCSC:Q16539 MAPK14
Reference Transcript
RefSeq:NM_139013.2 MAPK14
RefSeq:NM_001315.2 MAPK14
RefSeq:NM_139012.2 MAPK14
RefSeq:NM_139014.2 MAPK14
Other Identifiers
0000380088
0005910181
11717276_s_at
11742204_a_at
11742487_a_at
11749297_a_at
11753885_a_at
1432
1671_s_at
17007884
1999_s_at
202530_at
210449_x_at
211087_3p_x_at
211087_x_at
211561_x_at
232876_at
2904878
2904879
2904884
2904885
2904889
2904891
2904892
2904894
2904896
2904907
2904910
2904913
2904914
2904919
2904920
2904921
2904922
2904923
2904924
2904925
2904930
2904932
37733_at
78240_at
8119000
A_14_P111428
A_23_P426292
A_24_P283288
A_24_P397566
GE492524
GE57735
GO:0000003
GO:0000077
GO:0000166
GO:0000187
GO:0000902
GO:0000922
GO:0001502
GO:0001525
GO:0001890
GO:0002062
GO:0002376
GO:0002720
GO:0003674
GO:0004672
GO:0004674
GO:0004707
GO:0004708
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005829
GO:0005856
GO:0005975
GO:0006006
GO:0006355
GO:0006357
GO:0006464
GO:0006468
GO:0006629
GO:0006810
GO:0006913
GO:0006915
GO:0006935
GO:0006950
GO:0006974
GO:0007049
GO:0007165
GO:0007166
GO:0007178
GO:0007265
GO:0007267
GO:0007519
GO:0007568
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0009056
GO:0009058
GO:0010468
GO:0010628
GO:0010759
GO:0010831
GO:0015031
GO:0016192
GO:0016301
GO:0016310
GO:0016607
GO:0016740
GO:0018105
GO:0019395
GO:0019899
GO:0019903
GO:0030154
GO:0030278
GO:0030316
GO:0031281
GO:0031410
GO:0031663
GO:0032495
GO:0032496
GO:0032735
GO:0034641
GO:0034655
GO:0034774
GO:0035331
GO:0035556
GO:0035924
GO:0035994
GO:0038066
GO:0040007
GO:0040011
GO:0042307
GO:0042592
GO:0042770
GO:0043167
GO:0043226
GO:0043312
GO:0044281
GO:0045648
GO:0045663
GO:0045944
GO:0046326
GO:0048010
GO:0048273
GO:0048646
GO:0048856
GO:0048870
GO:0051090
GO:0051146
GO:0051149
GO:0051525
GO:0055085
GO:0060045
GO:0070935
GO:0071222
GO:0071223
GO:0071356
GO:0071479
GO:0090090
GO:0090336
GO:0090400
GO:0098586
GO:1900015
GO:1901741
GO:1901796
GO:1904813
GO:1905050
GO:2000379
Hs.258010.0.S1_3p_at
ILMN_1737627
ILMN_1788002
ILMN_2388090
L35253_s_at
L35263_at
PH_hs_0004571
PH_hs_0020050
TC06000523.hg
g405742_3p_s_at
g4503068_3p_at
g7109716_3p_a_at
Participant Of
hasMember
Secretory granule lumen proteins [secretory granule lumen]
Other forms of this molecule
MAPK14 [ficolin-1-rich granule lumen]
MAPK14 [extracellular region]
MAPK14 [nucleoplasm]
MAPK14 [cytosol]
p-T180,Y182-MAPK14 [cytosol]
p-T180,Y182-MAPK14 [nucleoplasm]
Inferred To
SLT2 [secretory granule lumen] (Saccharomyces cerevisiae)
spm1 [secretory granule lumen] (Schizosaccharomyces pombe)
SMK1 [secretory granule lumen] (Saccharomyces cerevisiae)
p38b [secretory granule lumen] (Drosophila melanogaster)
mapk14b [secretory granule lumen] (Danio rerio)
Mapk14 [secretory granule lumen] (Mus musculus)
Mapk14 [secretory granule lumen] (Rattus norvegicus)
pmk-1 [secretory granule lumen] (Caenorhabditis elegans)
Homologues of MAPK14 [secretory granule lumen] (Danio rerio)
Homologues of MAPK14 [secretory granule lumen] (Dictyostelium discoideum)
Homologues of MAPK14 [secretory granule lumen] (Plasmodium falciparum)
Homologues of MAPK14 [secretory granule lumen] (Saccharomyces cerevisiae)
Homologues of MAPK14 [secretory granule lumen] (Schizosaccharomyces pombe)
sty1 [secretory granule lumen] (Schizosaccharomyces pombe)
mapk14a [secretory granule lumen] (Danio rerio)
MAPK14 [secretory granule lumen] (Bos taurus)
MAPK14 [secretory granule lumen] (Canis familiaris)
MAPK14 [secretory granule lumen] (Dictyostelium discoideum)
MAPK14 [secretory granule lumen] (Gallus gallus)
MAPK14 [secretory granule lumen] (Plasmodium falciparum)
MAPK14 [secretory granule lumen] (Sus scrofa)
MAPK14 [secretory granule lumen] (Xenopus tropicalis)
erkA [secretory granule lumen] (Dictyostelium discoideum)
HOG1 [secretory granule lumen] (Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001306.1
,
NP_620581.1
,
NP_620582.1
,
NP_620583.1
ZINC - World Drugs
MK14_HUMAN
OpenTargets
ENSG00000112062
ZINC - FDA approved
MK14_HUMAN
ZINC - Substances
MK14_HUMAN
ZINC target
Q16539
ZINC - Biogenic
MK14_HUMAN
PRO
Q16539
PDB
1WBN
,
1M7Q
,
1ZYJ
,
3HV3
,
3E92
,
3DT1
,
1BL7
,
4E6C
,
4L8M
,
4E8A
,
3ZS5
,
4KIP
,
3GCS
,
3LFE
,
1OZ1
,
3HA8
,
4EH7
,
3BV3
,
3FMN
,
3FKN
,
3FML
,
5ETF
,
3MVL
,
2RG6
,
3IW6
,
3LFB
,
3MH0
,
3HL7
,
1WFC
,
2ONL
,
3ZSG
,
3OBG
,
2Y8O
,
2YIX
,
5N64
,
3S4Q
,
4EHV
,
1WBW
,
5MZ3
,
2NPQ
,
1DI9
,
3ODY
,
2BAK
,
2ZAZ
,
3GFE
,
3L8X
,
6SFK
,
3GC7
,
3OC1
,
6HWV
,
1KV1
,
5XYX
,
1W83
,
3FLZ
,
3IW5
,
3UVR
,
3K3I
,
4EH8
,
2OKR
,
3FLN
,
3FSF
,
3QUD
,
5TBE
,
6QE1
,
3MH3
,
1R39
,
3D83
,
6M9L
,
4E5B
,
3OCG
,
4EWQ
,
3UVP
,
6HWT
,
5ETA
,
3FC1
,
3FLW
,
3HRB
,
4KIQ
,
3GCU
,
6QYX
,
1W7H
,
3HLL
,
3FKO
,
3ZSI
,
1WBT
,
3HV6
,
3LFC
,
3IW8
,
3FMM
,
2YIS
,
5TCO
,
3NNW
,
3BX5
,
4EH3
,
3ZSH
,
3HUB
,
3U8W
,
3FMJ
,
3LFA
,
4EH4
,
3PG3
,
3FI4
,
4DLJ
,
5N65
,
5O8V
,
6TCA
,
3GCP
,
5OMG
,
6SFI
,
2LGC
,
4E5A
,
1OUY
,
1A9U
,
4FA2
,
3MPT
,
3NEW
,
1KV2
,
1YQJ
,
6SFO
,
3IW7
,
4AA5
,
3GI3
,
2FSO
,
4F9W
,
3ZYA
,
4EH9
,
4EH2
,
3FMH
,
4R3C
,
1BMK
,
5ML5
,
5OMH
,
4GEO
,
1R3C
,
3RIN
,
3LHJ
,
3LFF
,
6HWU
,
2QD9
,
5N68
,
3FSK
,
2FSL
,
3NNX
,
3CTQ
,
1WBO
,
6ANL
,
3MH1
,
5MTX
,
3GCQ
,
3DS6
,
1WBV
,
5N63
,
3HP2
,
3HV7
,
3HV4
,
3FMK
,
3NNU
,
3ITZ
,
2YIW
,
6SFJ
,
5N66
,
2ZB0
,
5WJJ
,
1IAN
,
4DLI
,
3QUE
,
2BAL
,
3FLQ
,
2FST
,
3L8S
,
3OBJ
,
3O8T
,
3FKL
,
5ETI
,
1W84
,
3FLY
,
3ODZ
,
3E93
,
4AAC
,
5XYY
,
4EH5
,
3UVQ
,
3NWW
,
1BL6
,
4F9Y
,
3GCV
,
3C5U
,
3O8P
,
4ZTH
,
3FL4
,
4E6A
,
4A9Y
,
3MGY
,
2RG5
,
3HUC
,
4EH6
,
2FSM
,
1WBS
,
3HP5
,
3LFD
,
3MW1
,
5MTY
,
3BV2
,
3MH2
,
5ETC
,
4AA4
,
3NNV
,
2GFS
,
5O8U
,
3KF7
,
1ZZL
,
3HEG
,
3HV5
,
4AA0
,
2ZB1
,
5N67
,
3HEC
,
3IPH
,
2BAJ
,
3KQ7
,
3ROC
,
2BAQ
,
3HVC
,
3D7Z
,
3MVM
,
1ZZ2
,
6OHD
,
1OVE
,
3FLS
,
1OUK
,
3S3I
,
1W82
,
6M95
,
3K3J
,
3O8U
,
3OEF
,
3OD6
,
2I0H
,
6RFO
,
6QDZ
,
3MPA
,
4KIN
ZINC - Investigational
MK14_HUMAN
ZINC - Metabolites
MK14_HUMAN
HPA
ENSG00000112062-MAPK14
GeneCards
Q16539
Ensembl
ENST00000310795
,
ENSP00000229794
,
ENSG00000112062
,
ENSP00000308669
,
ENSP00000229795
,
ENST00000229795
,
ENST00000229794
ZINC - Predictions - Purchasable
MK14_HUMAN
HMDB Protein
HMDBP01516
Interactors (24)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P49137 MAPKAPK2
5
p-T222,S272-MAPKAPK2 [nucleoplasm]
(R-HSA-199936)
MAPKAPK2 [cytosol]
(R-HSA-187743)
p-S272,T222,T334-MAPKAPK2 [cytosol]
(R-HSA-187760)
p-T222,S272,T334-MAPKAPK2 [nucleoplasm]
(R-HSA-450268)
MAPKAPK2 [nucleoplasm]
(R-HSA-450235)
0.912
9
UniProt:Q16644 MAPKAPK3
4
p-S,2T-MAPKAPK3 [cytosol]
(R-HSA-187723)
MAPKAPK3 [cytosol]
(R-HSA-187764)
p-S,2T-MAPKAPK3 [nucleoplasm]
(R-HSA-450359)
MAPKAPK3 [nucleoplasm]
(R-HSA-450218)
0.891
8
UniProt:O75676 RPS6KA4
1
RPS6KA4 [cytosol]
(R-HSA-772527)
0.779
6
UniProt:Q8NEM7 SUPT20H
1
SUPT20H [nucleoplasm]
(R-HSA-3662286)
0.756
5
UniProt:Q15750 TAB1
2
TAB1 [cytosol]
(R-HSA-167923)
TAB1 [endosome membrane]
(R-HSA-450238)
0.729
4
UniProt:O43257 ZNHI1
0.72
7
UniProt:P28562 DUSP1
1
DUSP1 [nucleoplasm]
(R-HSA-203796)
0.704
3
UniProt:P27361 MAPK3
6
p-T202-MAPK3 [cytosol]
(R-HSA-9635775)
MAPK3 [endoplasmic reticulum lumen]
(R-HSA-9636295)
MAPK3 [nucleoplasm]
(R-HSA-73724)
p-T202,Y204-MAPK3 [nucleoplasm]
(R-HSA-112359)
p-T202,Y204-MAPK3 [cytosol]
(R-HSA-109842)
MAPK3 [cytosol]
(R-HSA-59284)
0.704
5
UniProt:Q9HBH9 MKNK2
0.678
3
UniProt:P46734 MAP2K3
3
p-S189,T193-MAP2K3 [cytosol]
(R-HSA-167955)
MAP2K3 [cytosol]
(R-HSA-168051)
p-S189,T193-MAP2K3 [nucleoplasm]
(R-HSA-450229)
0.669
4
UniProt:Q9BUB5 MKNK1
1
p-T250,T255,T385,S437-MKNK1 [cytosol]
(R-HSA-947860)
0.659
3
UniProt:P06400 RB1
394
RB1 C706F [nucleoplasm]
(R-HSA-9659812)
RB1 R661W [nucleoplasm]
(R-HSA-9659801)
RB1 N480del [nucleoplasm]
(R-HSA-9659792)
RB1 C706Y [nucleoplasm]
(R-HSA-9659821)
RB1 R661Q [nucleoplasm]
(R-HSA-9659807)
RB1 I703_E737del [nucleoplasm]
(R-HSA-9661065)
RB1 R830_G887del [cytosol]
(R-HSA-9661059)
RB1 K791* [cytosol]
(R-HSA-9662284)
RB1 Q176* [cytosol]
(R-HSA-9661774)
RB1 S114* [cytosol]
(R-HSA-9661775)
RB1 K765* [cytosol]
(R-HSA-9662281)
RB1 W99* [cytosol]
(R-HSA-9661769)
RB1 S149* [cytosol]
(R-HSA-9661770)
RB1 E166* [cytosol]
(R-HSA-9661767)
RB1 G100* [cytosol]
(R-HSA-9661763)
RB1 E125* [cytosol]
(R-HSA-9661784)
RB1 Q121* [cytosol]
(R-HSA-9661780)
RB1 E184* [cytosol]
(R-HSA-9661781)
RB1 E137* [cytosol]
(R-HSA-9661782)
RB1 K745* [cytosol]
(R-HSA-9662288)
RB1 E209* [cytosol]
(R-HSA-9661776)
RB1 S618* [cytosol]
(R-HSA-9662240)
RB1 S463* [cytosol]
(R-HSA-9662241)
RB1 K720* [cytosol]
(R-HSA-9662269)
RB1 K429* [cytosol]
(R-HSA-9662270)
RB1 K652* [cytosol]
(R-HSA-9662271)
RB1 K715* [cytosol]
(R-HSA-9662264)
RB1 K615* [cytosol]
(R-HSA-9662266)
RB1 K412* [cytosol]
(R-HSA-9662261)
RB1 S567* [cytosol]
(R-HSA-9662218)
RB1 S807* [cytosol]
(R-HSA-9662212)
RB1 R467* [cytosol]
(R-HSA-9662213)
RB1 S834* [cytosol]
(R-HSA-9662210)
RB1 S576* [cytosol]
(R-HSA-9662237)
RB1 S758* [cytosol]
(R-HSA-9662232)
RB1 R7Pfs*24 [cytosol]
(R-HSA-9686292)
RB1 S443* [cytosol]
(R-HSA-9662230)
RB1 S648* [cytosol]
(R-HSA-9662224)
RB1 S391* [cytosol]
(R-HSA-9662225)
RB1 S829* [cytosol]
(R-HSA-9662226)
RB1 D32Tfs*33 [cytosol]
(R-HSA-9688044)
RB1 Y651Ifs*7 [cytosol]
(R-HSA-9688045)
RB1 K143Mfs*19 [cytosol]
(R-HSA-9688046)
RB1 V754Sfs*4 [cytosol]
(R-HSA-9688047)
RB1 L44Rfs*4 [cytosol]
(R-HSA-9688040)
RB1 E97Gfs*13 [cytosol]
(R-HSA-9688041)
RB1 I679* [cytosol]
(R-HSA-9688042)
RB1 W195* [cytosol]
(R-HSA-9689579)
RB1 G100Efs*11 [cytosol]
(R-HSA-9688043)
RB1 S648Tfs*4 [cytosol]
(R-HSA-9688036)
RB1 H281Qfs*6 [cytosol]
(R-HSA-9688037)
RB1 Q384* [cytosol]
(R-HSA-9661925)
RB1 S182Yfs*2 [cytosol]
(R-HSA-9688038)
RB1 L343Sfs*3 [cytosol]
(R-HSA-9688039)
RB1 L337Wfs*12 [cytosol]
(R-HSA-9688032)
RB1 S318* [cytosol]
(R-HSA-9688033)
RB1 N627Mfs*16 [cytosol]
(R-HSA-9688034)
RB1 N290Kfs*20 [cytosol]
(R-HSA-9688035)
RB1 F299Lfs*4 [cytosol]
(R-HSA-9688060)
RB1 Q637* [cytosol]
(R-HSA-9662460)
RB1 L76* [cytosol]
(R-HSA-9688061)
RB1 Q762* [cytosol]
(R-HSA-9662461)
RB1 Y655Lfs*4 [cytosol]
(R-HSA-9688062)
RB1 N480Kfs*13 [cytosol]
(R-HSA-9688063)
RB1 Q444* [cytosol]
(R-HSA-9662463)
RB1 T77Lfs*34 [cytosol]
(R-HSA-9688056)
RB1 E747Gfs*3 [cytosol]
(R-HSA-9688057)
RB1 M825* [cytosol]
(R-HSA-9688058)
RB1 L649Ffs*11 [cytosol]
(R-HSA-9688059)
RB1 N472Ifs*6 [cytosol]
(R-HSA-9688052)
RB1 Y813Kfs*12 [cytosol]
(R-HSA-9688053)
RB1 I324Mfs*17 [cytosol]
(R-HSA-9688054)
RB1 M460Ifs*3 [cytosol]
(R-HSA-9688055)
RB1 Y655Ifs*3 [cytosol]
(R-HSA-9688048)
RB1 L769Cfs*41 [cytosol]
(R-HSA-9688049)
RB1 P28Lfs*37 [cytosol]
(R-HSA-9688050)
RB1 E677Dfs*19 [cytosol]
(R-HSA-9688051)
RB1 P370Lfs*10 [cytosol]
(R-HSA-9688012)
RB1 N593Tfs*11 [cytosol]
(R-HSA-9688013)
RB1 K329* [cytosol]
(R-HSA-9661901)
RB1 S249Ffs*22 [cytosol]
(R-HSA-9688014)
RB1 K240* [cytosol]
(R-HSA-9661902)
RB1 L199Ffs*4 [cytosol]
(R-HSA-9688015)
RB1 P253Gfs*5 [cytosol]
(R-HSA-9688008)
RB1 K289* [cytosol]
(R-HSA-9661896)
RB1 S360Pfs*2 [cytosol]
(R-HSA-9688009)
RB1 E323Kfs*9 [cytosol]
(R-HSA-9688010)
RB1 L326* [cytosol]
(R-HSA-9688011)
RB1 P808Kfs*12 [cytosol]
(R-HSA-9688004)
RB1 D584Nfs*2 [cytosol]
(R-HSA-9688005)
RB1 N406Kfs*4 [cytosol]
(R-HSA-9688006)
RB1 K417Wfs*23 [cytosol]
(R-HSA-9688007)
RB1 L797Ffs*18 [cytosol]
(R-HSA-9688000)
RB1 Q266Hfs*2 [cytosol]
(R-HSA-9688001)
RB1 R255* [cytosol]
(R-HSA-9661889)
RB1 K4* [cytosol]
(R-HSA-9661377)
RB1 P641Afs*12 [cytosol]
(R-HSA-9688002)
RB1 V450Sfs*13 [cytosol]
(R-HSA-9688003)
RB1 K524Rfs*28 [cytosol]
(R-HSA-9688028)
RB1 E280* [cytosol]
(R-HSA-9661916)
RB1 M825Ifs*13 [cytosol]
(R-HSA-9688029)
RB1 M761Nfs*21 [cytosol]
(R-HSA-9688030)
RB1 A11Rfs*20 [cytosol]
(R-HSA-9688031)
RB1 E275* [cytosol]
(R-HSA-9661919)
RB1 A635Gfs*6 [cytosol]
(R-HSA-9688024)
RB1 Q266* [cytosol]
(R-HSA-9661912)
RB1 I66Yfs*11 [cytosol]
(R-HSA-9688025)
RB1 Q257* [cytosol]
(R-HSA-9661913)
RB1 P39Rfs*26 [cytosol]
(R-HSA-9688026)
RB1 T664Nfs*4 [cytosol]
(R-HSA-9688027)
RB1 Y771Lfs*24 [cytosol]
(R-HSA-9688020)
RB1 R320Dfs*12 [cytosol]
(R-HSA-9688021)
RB1 E282* [cytosol]
(R-HSA-9661909)
RB1 L277Pfs*9 [cytosol]
(R-HSA-9688022)
RB1 I124* [cytosol]
(R-HSA-9688023)
RB1 N803Tfs*7 [cytosol]
(R-HSA-9688016)
RB1 M386Ifs*11 [cytosol]
(R-HSA-9688017)
RB1 E72Vfs*34 [cytosol]
(R-HSA-9688018)
RB1 R150Kfs*7 [cytosol]
(R-HSA-9688019)
RB1 L743* [cytosol]
(R-HSA-9687980)
RB1 R7Efs*58 [cytosol]
(R-HSA-9687981)
RB1 T140Nfs*6 [cytosol]
(R-HSA-9687982)
RB1 D479Efs*16 [cytosol]
(R-HSA-9687983)
RB1 L199* [cytosol]
(R-HSA-9661871)
RB1 G801* [cytosol]
(R-HSA-9662377)
RB1 S215* [cytosol]
(R-HSA-9661866)
RB1 G435* [cytosol]
(R-HSA-9662368)
RB1 G581* [cytosol]
(R-HSA-9662369)
RB1 L134* [cytosol]
(R-HSA-9687996)
RB1 Y529Lfs*26 [cytosol]
(R-HSA-9687997)
RB1 S816Qfs*10 [cytosol]
(R-HSA-9687998)
RB1 E693Nfs*3 [cytosol]
(R-HSA-9687999)
RB1 D346Rfs*4 [cytosol]
(R-HSA-9687992)
RB1 Q35* [cytosol]
(R-HSA-9661368)
RB1 I806Lfs*10 [cytosol]
(R-HSA-9687993)
RB1 E54* [cytosol]
(R-HSA-9661369)
RB1 L199Yfs*2 [cytosol]
(R-HSA-9687994)
RB1 E48* [cytosol]
(R-HSA-9661370)
RB1 N854* [cytosol]
(R-HSA-9687995)
RB1 W75* [cytosol]
(R-HSA-9661371)
RB1 L389Ffs*3 [cytosol]
(R-HSA-9687988)
RB1 S230* [cytosol]
(R-HSA-9661876)
RB1 H483Sfs*10 [cytosol]
(R-HSA-9687989)
RB1 S842* [cytosol]
(R-HSA-9687990)
RB1 W78* [cytosol]
(R-HSA-9661366)
RB1 G449Efs*8 [cytosol]
(R-HSA-9687991)
RB1 K63* [cytosol]
(R-HSA-9661367)
RB1 K537Nfs*14 [cytosol]
(R-HSA-9687984)
RB1 L206* [cytosol]
(R-HSA-9661872)
RB1 K63Rfs*38 [cytosol]
(R-HSA-9687985)
RB1 P732Lfs*12 [cytosol]
(R-HSA-9687986)
RB1 L158* [cytosol]
(R-HSA-9661874)
RB1 A562Hfs*49 [cytosol]
(R-HSA-9687987)
RB1 E72* [cytosol]
(R-HSA-9661363)
RB1 G540Afs*3 [cytosol]
(R-HSA-9688172)
RB1 N328Ifs*4 [cytosol]
(R-HSA-9688173)
RB1 E843* [cytosol]
(R-HSA-9662573)
RB1 L385* [cytosol]
(R-HSA-9688174)
RB1 E464* [cytosol]
(R-HSA-9662574)
RB1 N123Tfs*2 [cytosol]
(R-HSA-9688175)
RB1 E112Dfs*6 [cytosol]
(R-HSA-9688168)
RB1 E748* [cytosol]
(R-HSA-9662568)
RB1 M148Ifs*8 [cytosol]
(R-HSA-9688169)
RB1 R661* [cytosol]
(R-HSA-9688170)
RB1 Y453* [cytosol]
(R-HSA-9688164)
RB1 K95* [cytosol]
(R-HSA-9661540)
RB1 M484Vfs*8 [cytosol]
(R-HSA-9688165)
RB1 E533* [cytosol]
(R-HSA-9662565)
RB1 G86* [cytosol]
(R-HSA-9661541)
RB1 V654Sfs*14 [cytosol]
(R-HSA-9688166)
RB1 E747* [cytosol]
(R-HSA-9662566)
RB1 E79* [cytosol]
(R-HSA-9661542)
RB1 C553Wfs*53 [cytosol]
(R-HSA-9688167)
RB1 E677* [cytosol]
(R-HSA-9662567)
RB1 K96* [cytosol]
(R-HSA-9661543)
RB1 C102Yfs*7 [cytosol]
(R-HSA-9688160)
RB1 E737* [cytosol]
(R-HSA-9662560)
RB1 E97* [cytosol]
(R-HSA-9661536)
RB1 R579Qfs*29 [cytosol]
(R-HSA-9688161)
RB1 A525Pfs*7 [cytosol]
(R-HSA-9688162)
RB1 L542Kfs*11 [cytosol]
(R-HSA-9688163)
RB1 F482Sfs*10 [cytosol]
(R-HSA-9688188)
RB1 L797* [cytosol]
(R-HSA-9688189)
RB1 P250Afs*16 [cytosol]
(R-HSA-9688190)
RB1 S194Ffs*7 [cytosol]
(R-HSA-9688191)
RB1 N623Qfs*15 [cytosol]
(R-HSA-9688184)
RB1 T9Rfs*56 [cytosol]
(R-HSA-9688185)
RB1 Y813Qfs*10 [cytosol]
(R-HSA-9688187)
RB1 I768Cfs*23 [cytosol]
(R-HSA-9688180)
RB1 L477Mfs*17 [cytosol]
(R-HSA-9688181)
RB1 E675* [cytosol]
(R-HSA-9662581)
RB1 V654Cfs*4 [cytosol]
(R-HSA-9688182)
RB1 F650Lfs*5 [cytosol]
(R-HSA-9688183)
RB1 P39Sfs*10 [cytosol]
(R-HSA-9688176)
RB1 H281Sfs*2 [cytosol]
(R-HSA-9688177)
RB1 E551* [cytosol]
(R-HSA-9662577)
RB1 C61Vfs*4 [cytosol]
(R-HSA-9688178)
RB1 D145Ifs*8 [cytosol]
(R-HSA-9688179)
RB1 M148Hfs*9 [cytosol]
(R-HSA-9688140)
RB1 E837* [cytosol]
(R-HSA-9662540)
RB1 L158Mfs*19 [cytosol]
(R-HSA-9688141)
RB1 L832Ffs*5 [cytosol]
(R-HSA-9688142)
RB1 E440* [cytosol]
(R-HSA-9662542)
RB1 D224Afs*40 [cytosol]
(R-HSA-9688136)
RB1 P822Qfs*4 [cytosol]
(R-HSA-9688137)
RB1 M148Vfs*8 [cytosol]
(R-HSA-9688138)
RB1 L670Cfs*7 [cytosol]
(R-HSA-9688139)
RB1 E465* [cytosol]
(R-HSA-9662532)
RB1 S414Kfs*14 [cytosol]
(R-HSA-9688133)
RB1 K548Nfs*3 [cytosol]
(R-HSA-9688134)
RB1 L135Tfs*5 [cytosol]
(R-HSA-9688135)
RB1 Q207Tfs*5 [cytosol]
(R-HSA-9688128)
RB1 Q384Tfs*11 [cytosol]
(R-HSA-9688129)
RB1 L797Ffs*14 [cytosol]
(R-HSA-9688130)
RB1 P232Rfs*4 [cytosol]
(R-HSA-9688131)
RB1 T497Hfs*22 [cytosol]
(R-HSA-9688156)
RB1 E817* [cytosol]
(R-HSA-9662556)
RB1 N367* [cytosol]
(R-HSA-9688157)
RB1 L809Rfs*17 [cytosol]
(R-HSA-9688158)
RB1 E693* [cytosol]
(R-HSA-9662558)
RB1 K80* [cytosol]
(R-HSA-9661534)
RB1 W99Lfs*11 [cytosol]
(R-HSA-9688159)
RB1 A15Pfs*3 [cytosol]
(R-HSA-9688152)
RB1 Y239Lfs*25 [cytosol]
(R-HSA-9688153)
RB1 D571Lfs*41 [cytosol]
(R-HSA-9688154)
RB1 N186Ifs*6 [cytosol]
(R-HSA-9688155)
RB1 E837Dfs*12 [cytosol]
(R-HSA-9688148)
RB1 E672* [cytosol]
(R-HSA-9662548)
RB1 H483Yfs*9 [cytosol]
(R-HSA-9688149)
RB1 R775Gfs*35 [cytosol]
(R-HSA-9688150)
RB1 E580* [cytosol]
(R-HSA-9662550)
RB1 G617Rfs*36 [cytosol]
(R-HSA-9688151)
RB1 E492* [cytosol]
(R-HSA-9662551)
RB1 A333Ffs*13 [cytosol]
(R-HSA-9688144)
RB1 L564Sfs*47 [cytosol]
(R-HSA-9688145)
RB1 D156Vfs*19 [cytosol]
(R-HSA-9688147)
RB1 C438Vfs*19 [cytosol]
(R-HSA-9688108)
RB1 C278* [cytosol]
(R-HSA-9688109)
RB1 E209Vfs*3 [cytosol]
(R-HSA-9688110)
RB1 T116Lfs*8 [cytosol]
(R-HSA-9688111)
RB1 R698Afs*22 [cytosol]
(R-HSA-9688104)
RB1 V419* [cytosol]
(R-HSA-9688105)
RB1 I415Nfs*13 [cytosol]
(R-HSA-9688106)
RB1 Y173Ffs*11 [cytosol]
(R-HSA-9688107)
RB1 N133Tfs*3 [cytosol]
(R-HSA-9688100)
RB1 M695Rfs*10 [cytosol]
(R-HSA-9688101)
RB1 R418Sfs*9 [cytosol]
(R-HSA-9688102)
RB1 Q689* [cytosol]
(R-HSA-9662502)
RB1 A74Efs*4 [cytosol]
(R-HSA-9688103)
RB1 W99Yfs*5 [cytosol]
(R-HSA-9688096)
RB1 G442Dfs*15 [cytosol]
(R-HSA-9688097)
RB1 N258Efs*11 [cytosol]
(R-HSA-9688098)
RB1 S182Ifs*3 [cytosol]
(R-HSA-9688099)
RB1 Q436* [cytosol]
(R-HSA-9662499)
RB1 Q395Pfs*11 [cytosol]
(R-HSA-9688124)
RB1 Y606Lfs*47 [cytosol]
(R-HSA-9688125)
RB1 E539* [cytosol]
(R-HSA-9662525)
RB1 L317* [cytosol]
(R-HSA-9688126)
RB1 F104Lfs*7 [cytosol]
(R-HSA-9688127)
RB1 E691* [cytosol]
(R-HSA-9662527)
RB1 D340Yfs*5 [cytosol]
(R-HSA-9688120)
RB1 K740Tfs*10 [cytosol]
(R-HSA-9688121)
RB1 H483Ifs*12 [cytosol]
(R-HSA-9688122)
RB1 R611Lfs*43 [cytosol]
(R-HSA-9688123)
RB1 V291Ifs*9 [cytosol]
(R-HSA-9688116)
RB1 N133* [cytosol]
(R-HSA-9688117)
RB1 R334* [cytosol]
(R-HSA-9688118)
RB1 D697Qfs*23 [cytosol]
(R-HSA-9688119)
RB1 L647Ffs*5 [cytosol]
(R-HSA-9688112)
RB1 I723Nfs*28 [cytosol]
(R-HSA-9688113)
RB1 L486Ifs*6 [cytosol]
(R-HSA-9688114)
RB1 S565* [cytosol]
(R-HSA-9688115)
RB1 Y529Tfs*3 [cytosol]
(R-HSA-9688076)
RB1 Q631* [cytosol]
(R-HSA-9662476)
RB1 S318Nfs*13 [cytosol]
(R-HSA-9688077)
RB1 D856Efs*17 [cytosol]
(R-HSA-9688078)
RB1 P595Lfs*16 [cytosol]
(R-HSA-9688079)
RB1 P777Lfs*33 [cytosol]
(R-HSA-9688072)
RB1 G310Dfs*22 [cytosol]
(R-HSA-9688073)
RB1 P250Sfs*20 [cytosol]
(R-HSA-9688074)
RB1 Q850* [cytosol]
(R-HSA-9662474)
RB1 I124Rfs*6 [cytosol]
(R-HSA-9688075)
RB1 Q702* [cytosol]
(R-HSA-9662475)
RB1 E748Dfs*6 [cytosol]
(R-HSA-9688068)
RB1 Q736* [cytosol]
(R-HSA-9662468)
RB1 R798Qfs*4 [cytosol]
(R-HSA-9688069)
RB1 S588Ffs*6 [cytosol]
(R-HSA-9688070)
RB1 K574* [cytosol]
(R-HSA-9688071)
RB1 D156Mfs*19 [cytosol]
(R-HSA-9688064)
RB1 Y771Cfs*23 [cytosol]
(R-HSA-9688065)
RB1 I66Dfs*44 [cytosol]
(R-HSA-9688066)
RB1 Q685* [cytosol]
(R-HSA-9662466)
RB1 E125Kfs*11 [cytosol]
(R-HSA-9688067)
RB1 Y655Lfs*13 [cytosol]
(R-HSA-9688092)
RB1 R828Kfs*10 [cytosol]
(R-HSA-9688093)
RB1 Y659Ifs*4 [cytosol]
(R-HSA-9688094)
RB1 Q846* [cytosol]
(R-HSA-9662494)
RB1 E97Nfs*14 [cytosol]
(R-HSA-9688095)
RB1 Q770* [cytosol]
(R-HSA-9662495)
RB1 C666* [cytosol]
(R-HSA-9688088)
RB1 Q471* [cytosol]
(R-HSA-9662488)
RB1 R71Efs*39 [cytosol]
(R-HSA-9688089)
RB1 Q504* [cytosol]
(R-HSA-9662489)
RB1 R798Tfs*17 [cytosol]
(R-HSA-9688090)
RB1 Q639* [cytosol]
(R-HSA-9662490)
RB1 N328* [cytosol]
(R-HSA-9688091)
RB1 S576Rfs*34 [cytosol]
(R-HSA-9688084)
RB1 T726Nfs*25 [cytosol]
(R-HSA-9688085)
RB1 Q597* [cytosol]
(R-HSA-9662485)
RB1 I532Nfs*57 [cytosol]
(R-HSA-9688086)
RB1 K577Rfs*34 [cytosol]
(R-HSA-9688087)
RB1 R73Sfs*36 [cytosol]
(R-HSA-9688080)
RB1 E413Kfs*4 [cytosol]
(R-HSA-9688081)
RB1 K844Sfs*5 [cytosol]
(R-HSA-9688082)
RB1 A17Pfs*3 [cytosol]
(R-HSA-9688083)
RB1 Q395* [cytosol]
(R-HSA-9660655)
RB1 L523* [cytosol]
(R-HSA-9662176)
RB1 R251* [cytosol]
(R-HSA-9660640)
RB1 L389* [cytosol]
(R-HSA-9662178)
RB1 Q217* [cytosol]
(R-HSA-9660668)
RB1 Q344* [cytosol]
(R-HSA-9660669)
RB1 S634* [cytosol]
(R-HSA-9662207)
RB1 S565* [cytosol]
(R-HSA-9662200)
RB1 S397* [cytosol]
(R-HSA-9662202)
RB1 S838* [cytosol]
(R-HSA-9662203)
RB1 R556* [cytosol]
(R-HSA-9660661)
RB1 R787* [cytosol]
(R-HSA-9660656)
RB1 G304* [cytosol]
(R-HSA-9662152)
RB1 W516* [cytosol]
(R-HSA-9662660)
RB1 W681* [cytosol]
(R-HSA-9662661)
RB1 E322* [cytosol]
(R-HSA-9662149)
RB1 W563* [cytosol]
(R-HSA-9662656)
RB1 L550* [cytosol]
(R-HSA-9662173)
RB1 R552* [cytosol]
(R-HSA-9660637)
RB1 L512* [cytosol]
(R-HSA-9662168)
RB1 R455* [cytosol]
(R-HSA-9660632)
RB1 R763* [cytosol]
(R-HSA-9662681)
RB1 L779* [cytosol]
(R-HSA-9662169)
RB1 R445* [cytosol]
(R-HSA-9660633)
RB1 R544* [cytosol]
(R-HSA-9662677)
RB1 R320* [cytosol]
(R-HSA-9660630)
RB1 L832* [cytosol]
(R-HSA-9662167)
RB1 Y498* [cytosol]
(R-HSA-9662634)
RB1 Y446* [cytosol]
(R-HSA-9662628)
RB1 Y655* [cytosol]
(R-HSA-9662629)
RB1 E323* [cytosol]
(R-HSA-9662142)
RB1 E364* [cytosol]
(R-HSA-9662143)
RB1 C489* [cytosol]
(R-HSA-9662649)
RB1 G310* [cytosol]
(R-HSA-9662137)
RB1 L335* [cytosol]
(R-HSA-9662139)
RB1 E313* [cytosol]
(R-HSA-9662133)
RB1 E315* [cytosol]
(R-HSA-9662131)
RB1 D479Vfs*14 [cytosol]
(R-HSA-9688204)
RB1 C489Lfs*5 [cytosol]
(R-HSA-9688205)
RB1 Y454* [cytosol]
(R-HSA-9662605)
RB1 E137Rfs*3 [cytosol]
(R-HSA-9688206)
RB1 L676Ffs*16 [cytosol]
(R-HSA-9688207)
RB1 Y728* [cytosol]
(R-HSA-9662607)
RB1 I799Ffs*11 [cytosol]
(R-HSA-9688200)
RB1 D346Vfs*17 [cytosol]
(R-HSA-9688201)
RB1 F514Pfs*8 [cytosol]
(R-HSA-9688202)
RB1 N593Sfs*5 [cytosol]
(R-HSA-9688203)
RB1 T58Yfs*52 [cytosol]
(R-HSA-9688196)
RB1 N522Ifs*2 [cytosol]
(R-HSA-9688197)
RB1 C553Vfs*58 [cytosol]
(R-HSA-9688198)
RB1 P609Cfs*43 [cytosol]
(R-HSA-9688199)
RB1 N269* [cytosol]
(R-HSA-9688192)
RB1 E287Rfs*2 [cytosol]
(R-HSA-9688193)
RB1 E492Lfs*4 [cytosol]
(R-HSA-9688194)
RB1 Q383Nfs*3 [cytosol]
(R-HSA-9688195)
RB1 Y606* [cytosol]
(R-HSA-9662617)
RB1 Y756* [cytosol]
(R-HSA-9662619)
RB1 Y790* [cytosol]
(R-HSA-9662612)
RB1 T502Nfs*17 [cytosol]
(R-HSA-9688208)
RB1 Y709* [cytosol]
(R-HSA-9662608)
RB1 Y749* [cytosol]
(R-HSA-9662611)
RB1 T738_R775del [nucleoplasm]
(R-HSA-9661042)
RB1 [cytosol]
(R-HSA-9660621)
hyperphosphorylated RB1 [nucleoplasm]
(R-HSA-188389)
p-S249-RB1 [nucleoplasm]
(R-HSA-9687343)
p-S230-RB1 [nucleoplasm]
(R-HSA-9687336)
p-T356-RB1 [nucleoplasm]
(R-HSA-9687339)
p-T826-RB1 [nucleoplasm]
(R-HSA-9687334)
p-S252-RB1 [nucleoplasm]
(R-HSA-9687335)
p-S807-RB1 [nucleoplasm]
(R-HSA-9687356)
p-T821-RB1 [nucleoplasm]
(R-HSA-9687357)
p-S795-RB1 [nucleoplasm]
(R-HSA-69226)
p-S612-RB1 [nucleoplasm]
(R-HSA-9687352)
p-S780-RB1 [nucleoplasm]
(R-HSA-9687353)
p-S811-RB1 [nucleoplasm]
(R-HSA-9687354)
RB1 [nucleoplasm]
(R-HSA-68642)
p-S788-RB1 [nucleoplasm]
(R-HSA-9687347)
p-S608-RB1 [nucleoplasm]
(R-HSA-9687351)
p-T373-RB1 [nucleoplasm]
(R-HSA-9687355)
0.623
4
UniProt:P48730-2 CSNK1D
0.556
3
UniProt:Q15256 PTPRR
0.556
3
UniProt:Q9H869 YYAP1
0.553
2
UniProt:Q15759 MAPK11
4
p-T180,Y182-MAPK11 [cytosol]
(R-HSA-171009)
MAPK11 [cytosol]
(R-HSA-170989)
MAPK11 [nucleoplasm]
(R-HSA-203790)
p-T180,Y182-MAPK11 [nucleoplasm]
(R-HSA-198741)
0.547
2
UniProt:P68104 EEF1A1
7
EEF1A1 [cytosol]
(R-HSA-156905)
EEF1A1 [lysosomal membrane]
(R-HSA-9626022)
EEF1A1 [secretory granule lumen]
(R-HSA-6801479)
EEF1A1 [extracellular region]
(R-HSA-6806456)
EEF1A1 [ficolin-1-rich granule lumen]
(R-HSA-6801528)
Me3K318-EEF1A1 [cytosol]
(R-HSA-8932419)
Me3K79-EEF1A1 [cytosol]
(R-HSA-8932212)
0.547
3
UniProt:Q9H0W5 CCDC8
1
CCDC8 [cytosol]
(R-HSA-8955915)
0.527
2
UniProt:O75147 OBSL1
1
OBSL1 [cytosol]
(R-HSA-8955929)
0.527
2
UniProt:P46940 IQGAP1
3
IQGAP1 [secretory granule membrane]
(R-HSA-6804803)
IQGAP1 [cytosol]
(R-HSA-5626371)
IQGAP1 [plasma membrane]
(R-HSA-381681)
0.527
3
UniProt:P13639 EEF2
10
EEF2 [extracellular region]
(R-HSA-6806499)
EEF2 [secretory granule lumen]
(R-HSA-6801504)
EEF2 [ficolin-1-rich granule lumen]
(R-HSA-6801513)
aminocarboxypropyl EEF2 [cytosol]
(R-HSA-5358478)
Me-diphthine EEF2 [cytosol]
(R-HSA-5367025)
nascent EEF2 [cytosol]
(R-HSA-5358472)
diphthine EEF2 [cytosol]
(R-HSA-5358501)
EEF2 [cytosol]
(R-HSA-156901)
ADP-ribo-EEF2 [cytosol]
(R-HSA-5334764)
Me3K525-EEF2 [cytosol]
(R-HSA-8932237)
0.527
2
UniProt:Q92574 TSC1
2
TSC1 [cytosol]
(R-HSA-5672338)
TSC1 [plasma membrane]
(R-HSA-165169)
0.508
2
UniProt:Q99956 DUSP9
1
DUSP9 [cytosol]
(R-HSA-5675351)
0.508
2
UniProt:Q07352 ZFP36L1
3
ZFP36L1 [cytosol]
(R-HSA-450547)
p-S54,S92,S203-p-ZFP36L1 [cytosol]
(R-HSA-450384)
p-S92,S203-ZFP36L1 [cytosol]
(R-HSA-450618)
0.508
2
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