Reactome | FPR2 [specific granule membrane]

FPR2 [specific granule membrane]

Stable Identifier

R-HSA-6803319

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule membrane

Synonyms

FPRL1, LXA4 receptor, N-formyl peptide receptor 2, FPR2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P25090 FPR2

Gene Names

FPR2, FPRH1, FPRL1, LXA4R

Chain

chain:1-351

Reference Genes

BioGPS Gene:2358 FPR2

COSMIC (genes):FPR2 FPR2

CTD Gene:2358 FPR2

dbSNP Gene:2358 FPR2

ENSEMBL:ENSG00000171049 FPR2

ENSEMBL:ENSG00000171049.9 FPR2

HGNC:3827 FPR2

KEGG Gene (Homo sapiens):2358 FPR2

Monarch:2358 FPR2

NCBI Gene:2358 FPR2

OMIM:136538 FPR2

UCSC:P25090 FPR2

Reference Transcript

Other Identifiers

11734034_a_at

11734035_a_at

11739140_a_at

16864751

210772_PM_at

210772_at

210773_PM_s_at

210773_s_at

2358

37095_r_at

3839911

3839912

3839914

3839915

3839916

3839917

8030860

A_14_P200556

A_23_P55649

D10922_s_at

GE88015

GO:0001540

GO:0001774

GO:0001934

GO:0002376

GO:0002430

GO:0002768

GO:0004875

GO:0004930

GO:0004982

GO:0005124

GO:0005515

GO:0005737

GO:0005886

GO:0006629

GO:0006898

GO:0006935

GO:0006954

GO:0007155

GO:0007165

GO:0007166

GO:0007186

GO:0007193

GO:0007200

GO:0007204

GO:0016020

GO:0016192

GO:0019722

GO:0023052

GO:0030154

GO:0031410

GO:0032930

GO:0035579

GO:0036211

GO:0038023

GO:0038024

GO:0042742

GO:0043226

GO:0045089

GO:0048143

GO:0048856

GO:0048870

GO:0050728

GO:0050766

GO:0050918

GO:0060089

GO:0061903

GO:0070374

GO:0070821

GO:0090026

GO:0098542

GO:0101003

GO:1904646

HMNXSV003033568

ILMN_1740875

ILMN_2392569

PH_hs_0029057

PH_hs_0031471

TC19000788.hg

g1916075_3p_a_at

Participates

as a member of

Specific granule membrane proteins [specific granule membrane] (Homo sapiens)

Other forms of this molecule

FPR2 [ficolin-1-rich granule membrane]

FPR2 [tertiary granule membrane]

FPR2 [plasma membrane]

Inferred To

FPR2 [specific granule membrane] (Canis familiaris)

FPR2 [specific granule membrane] (Danio rerio)

FPR2 [specific granule membrane] (Gallus gallus)

FPR2 [specific granule membrane] (Rattus norvegicus)

Fpr2 [specific granule membrane] (Mus musculus)

LOC100491504 [specific granule membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001453.1, XP_006723183.1, XP_016882031.1, NP_001005738.1

Guide to Pharmacology - Targets

223

OpenTargets

ENSG00000171049

ZINC - Substances

FPR2_HUMAN

ZINC target

P25090

PRO

P25090

PDB

6LW5, 7T6S, 6OMM, 7T6U, 7WVX, 7WVW, 7WVV, 7T6V, 7WVY

HPA

ENSG00000171049-FPR2

GeneCards

P25090

Ensembl

ENSP00000468876, ENSG00000171049, ENST00000340023, ENST00000598953, ENST00000598776, ENSP00000340191, ENSP00000468897

Pharos - Targets

P25090

ZINC - Predictions - Purchasable

FPR2_HUMAN

HMDB Protein

HMDBP02158

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H0Q3 FXYD6	1	FXYD6 [plasma membrane] (R-HSA-2752104)	0.556	3
UniProt:Q8N386 LRC25			0.556	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:Q8WWF3 SSMM1			0.556	3
UniProt:P05090 APOD	1	APOD [extracellular region] (R-HSA-5216199)	0.556	3

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