Reactome | TNFAIP6 [tertiary granule lumen]

TNFAIP6 [tertiary granule lumen]

Stable Identifier

R-HSA-6803341

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

tertiary granule lumen

Synonyms

Tumor necrosis factor-inducible gene 6 protein, TSG6_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P98066 TNFAIP6

Gene Names

TNFAIP6, TSG6

Chain

signal peptide:1-17, chain:18-277

Reference Genes

BioGPS Gene:7130 TNFAIP6

COSMIC (genes):TNFAIP6 TNFAIP6

CTD Gene:7130 TNFAIP6

dbSNP Gene:7130 TNFAIP6

ENSEMBL:ENSG00000123610 TNFAIP6

ENSEMBL_homo_sapiens_GENE:ENSG00000123610.5 TNFAIP6

HGNC:11898 TNFAIP6

KEGG Gene (Homo sapiens):7130 TNFAIP6

Monarch:7130 TNFAIP6

NCBI Gene:7130 TNFAIP6

OMIM:600410 TNFAIP6

UCSC:P98066 TNFAIP6

Reference Transcript

RefSeq:NM_007115.3 TNFAIP6

Other Identifiers

11743636_at

1372_at

16886491

206025_PM_s_at

206025_s_at

206026_PM_s_at

206026_s_at

2510469

2510470

2510472

2510473

2510475

2510477

2510479

2510480

7130

8045688

A_14_P117400

A_23_P165624

GE57919

GO:0001550

GO:0001968

GO:0002376

GO:0003824

GO:0005509

GO:0005515

GO:0005540

GO:0005576

GO:0005615

GO:0006954

GO:0007155

GO:0007165

GO:0007267

GO:0016787

GO:0022414

GO:0023052

GO:0030154

GO:0030212

GO:0030335

GO:0030514

GO:0031410

GO:0043226

GO:0045668

GO:0045671

GO:0046872

GO:0048856

GO:0048870

GO:0050728

GO:0090024

GO:0106435

GO:1901135

GO:1903911

GO:1904724

GO:1904813

GO:1905590

HMNXSV003027693

Hs.29352.0.S1_3p_a_at

ILMN_1785732

ILMN_2123217

M31165_at

PH_hs_0024700

TC02000937.hg

g6005905_3p_a_at

Participates

as a member of

Tertiary granule lumen proteins [tertiary granule lumen] (Homo sapiens)

Other forms of this molecule

TNFAIP6 [extracellular region]

TNFAIP6 [ficolin-1-rich granule lumen]

Inferred To

Cubn2 [tertiary granule lumen] (Drosophila melanogaster)

TNFAIP6 [tertiary granule lumen] (Bos taurus)

TNFAIP6 [tertiary granule lumen] (Canis familiaris)

TNFAIP6 [tertiary granule lumen] (Mus musculus)

TNFAIP6 [tertiary granule lumen] (Sus scrofa)

Tnfaip6 [tertiary granule lumen] (Rattus norvegicus)

cubn-1 [tertiary granule lumen] (Caenorhabditis elegans)

tnfaip6 [tertiary granule lumen] (Xenopus tropicalis)

TNFIP6 [tertiary granule lumen] (Gallus gallus)

Cross References

RefSeq

NP_009046.2

OpenTargets

ENSG00000123610

HPA

ENSG00000123610-TNFAIP6

GeneCards

P98066

Ensembl

ENST00000243347, ENSG00000123610, ENSP00000243347

PRO

P98066

Pharos - Targets

P98066

HMDB Protein

HMDBP02345

PDB

2N40, 1O7B, 2WNO, 2PF5, 1O7C

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09038 FGF2	1	FGF2(10-155) [extracellular region] (R-HSA-189898)	0.611	3
UniProt:P10145 CXCL8	1	IL8 [extracellular region] (R-HSA-447095)	0.558	15
UniProt:P02751 FN1	10	FN1(32-2386) [platelet alpha granule lumen] (R-HSA-114620) FN1(32-271) [extracellular region] (R-HSA-3787935) FN1(272-2386) [extracellular region] (R-HSA-3788024) FN1(32-?) [extracellular region] (R-HSA-2533850) FN1(?-2386) [extracellular region] (R-HSA-2533841) FN1(32-1201)-p-7Y-ALK(1022-1620) fusion [plasma membrane] (R-HSA-9713462) FN1(32-1201)-ALK(1022-1620) fusion [plasma membrane] (R-HSA-9713459) p-FN1 [endoplasmic reticulum lumen] (R-HSA-8956937) FN1 [endoplasmic reticulum lumen] (R-HSA-8956708) FN1(32-2386) [extracellular region] (R-HSA-54851)	0.558	8

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