TP53 binds ZNF385A gene

Stable Identifier
R-HSA-6803425
Type
Reaction
Species
Homo sapiens
Compartment
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Summation

TP53 (p53) binds to at least one of the three putative p53 response elements in the promoter of the human ZNF385A (HZF) gene (Das et al. 2007). In the mouse Znf385a gene, the p53 response element is in the first intron and also binds Tp53 (Sugimoto et al. 2006).

Literature References
PubMed ID Title Journal Year
16382142 Hzf, a p53-responsive gene, regulates maintenance of the G2 phase checkpoint induced by DNA damage

Sugimoto, M, Gromley, A, Sherr, CJ

Mol. Cell. Biol. 2006
17719541 Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation

Das, S, Raj, L, Zhao, B, Kimura, Y, Bernstein, A, Aaronson, SA, Lee, SW

Cell 2007
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