TP53 binds the SFN gene

Stable Identifier
R-HSA-6803858
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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TP53 (p53) binds the p53 response element in the promoter region of the SFN (14-3-3 sigma) gene (Hermeking et al. 1997). Interaction between ZNF385A (HZF) and TP53 facilitates TP53 binding to the promoter of the SFN gene (Das et al. 2007).

Literature References
PubMed ID Title Journal Year
9659898 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression

Hermeking, H, Lengauer, C, Polyak, K, He, TC, Zhang, L, Thiagalingam, S, Kinzler, KW, Vogelstein, B

Mol. Cell 1997
17719541 Hzf Determines cell survival upon genotoxic stress by modulating p53 transactivation

Das, S, Raj, L, Zhao, B, Kimura, Y, Bernstein, A, Aaronson, SA, Lee, SW

Cell 2007
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