RNF34 or RFFL ubiquitinates phosphorylated TP53

Stable Identifier
R-HSA-6804441
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

E3 ubiquitin ligases RNF34 (CARP1) and RFFL (CARP2) can ubiquitinate TP53 (p53) phosphorylated at the N-terminus and target it for proteasome-mediated degradation (Yang et al. 2007).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ubiquitin protein ligase activity of RNF34,RFFL [nucleoplasm]
Physical Entity
Activity
Orthologous Events