Reactome | CXCR1 [secretory granule membrane]

CXCR1 [secretory granule membrane]

Stable Identifier

R-HSA-6804780

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule membrane

Synonyms

IL8RA, High affinity interleukin-8 receptor A

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P25024 CXCR1

Gene Names

CXCR1, CMKAR1, IL8RA

Chain

chain:1-350

Reference Genes

BioGPS Gene:3577 CXCR1

COSMIC (genes):CXCR1 CXCR1

CTD Gene:3577 CXCR1

dbSNP Gene:3577 CXCR1

ENSEMBL:ENSG00000163464 CXCR1

ENSEMBL_homo_sapiens_GENE:ENSG00000163464.8 CXCR1

HGNC:6026 CXCR1

KEGG Gene (Homo sapiens):3577 CXCR1

Monarch:3577 CXCR1

NCBI Gene:3577 CXCR1

OMIM:146929 CXCR1

UCSC:P25024 CXCR1

Reference Transcript

RefSeq:NM_000634.2 CXCR1

Other Identifiers

11733003_a_at

11751323_a_at

1352_at

1353_g_at

16908307

207094_PM_at

207094_at

2599318

2599319

2599320

2599321

2599322

2599323

2599324

2599325

3577

8058905

A_23_P67932

GO:0002376

GO:0002407

GO:0004918

GO:0004930

GO:0004950

GO:0005515

GO:0005886

GO:0006935

GO:0006955

GO:0007165

GO:0007166

GO:0007186

GO:0007204

GO:0009897

GO:0016020

GO:0016192

GO:0016493

GO:0016494

GO:0019722

GO:0019957

GO:0019959

GO:0023052

GO:0030593

GO:0030667

GO:0031410

GO:0031623

GO:0038112

GO:0043226

GO:0048870

GO:0060089

GO:0070098

HMNXSV003002917

ILMN_1662524

PH_hs_0011528

TC02002767.hg

TC02003832.hg

U11870_rna1_at

g4504680_3p_at

Participates

as a member of

Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)

Other forms of this molecule

CXCR1 [plasma membrane]

Inferred To

Cxcr1 [secretory granule membrane] (Mus musculus)

Cxcr1 [secretory granule membrane] (Rattus norvegicus)

npr-32 [secretory granule membrane] (Caenorhabditis elegans)

Homologues of CXCR1 [secretory granule membrane] (Bos taurus)

Homologues of CXCR1 [secretory granule membrane] (Canis familiaris)

Homologues of CXCR1 [secretory granule membrane] (Sus scrofa)

CXCR1 [secretory granule membrane] (Bos taurus)

CXCR1 [secretory granule membrane] (Canis familiaris)

CXCR1 [secretory granule membrane] (Gallus gallus)

CXCR1 [secretory granule membrane] (Sus scrofa)

CXCR2 [secretory granule membrane] (Bos taurus)

CXCR2 [secretory granule membrane] (Canis familiaris)

CXCR2 [secretory granule membrane] (Sus scrofa)

cxcr2 [secretory granule membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_000625.1

ZINC - World Drugs

CXCR1_HUMAN

Guide to Pharmacology - Targets

OpenTargets

ENSG00000163464

ZINC - FDA approved

CXCR1_HUMAN

ZINC - Substances

CXCR1_HUMAN

ZINC - Biogenic

CXCR1_HUMAN

ZINC target

P25024

PRO

P25024

PDB

2LNL, 6XMN, 1ILP, 8IC0, 1ILQ

ZINC - Investigational

CXCR1_HUMAN

ZINC - Metabolites

CXCR1_HUMAN

HPA

ENSG00000163464-CXCR1

GeneCards

P25024

Ensembl

ENSG00000163464, ENST00000295683, ENSP00000295683

Pharos - Targets

P25024

ZINC - Predictions - Purchasable

CXCR1_HUMAN

HMDB Protein

HMDBP07641

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NY35 CLDN1			0.556	3
UniProt:Q969F0 FATE1			0.556	3
UniProt:A5PKU2 A5PKU2			0.556	3
UniProt:P24593 IGFBP5	5	IGFBP5 [extracellular region] (R-HSA-381414) IGFBP5(21-163) [extracellular region] (R-HSA-381415) IGFBP5(164-272) [extracellular region] (R-HSA-381478) IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956738) p-IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956988)	0.556	3

Cite Us!