CDK2 phosphorylates TP53

Stable Identifier
R-HSA-6805109
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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CDK2, bound to CCNA (cyclin A), phosphorylates TP53 on serine residue S315 (Luciani et al. 2000).

Literature References
PubMed ID Title Journal Year
10884347 The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A

Luciani, MG, Hutchins, JR, Zheleva, D, Hupp, TR

J. Mol. Biol. 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cyclin-dependent protein serine/threonine kinase activity of CCNA:p-T160-CDK2 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created