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GPR83 [plasma membrane]
Stable Identifier
R-HSA-6805229
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Probable G-protein coupled receptor 83, GPR83_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (s) signalling events (Homo sapiens)
Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR83 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR83 [plasma membrane] (Homo sapiens)
Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR83 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR83 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gs complex dissociates (Homo sapiens)
GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR83 [plasma membrane] (Homo sapiens)
GPCRs that activate Gs [plasma membrane] (Homo sapiens)
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
GPR83 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYM4 GPR83
Gene Names
GPR83, GPR72, JP05, KIAA1540
Chain
signal peptide:1-16, chain:17-423
Reference Genes
BioGPS Gene:10888 GPR83
COSMIC (genes):GPR83 GPR83
CTD Gene:10888 GPR83
dbSNP Gene:10888 GPR83
ENSEMBL:ENSG00000123901 GPR83
ENSEMBL_homo_sapiens_GENE:ENSG00000123901.9 GPR83
HGNC:4523 GPR83
KEGG Gene (Homo sapiens):10888 GPR83
Monarch:10888 GPR83
NCBI Gene:10888 GPR83
OMIM:605569 GPR83
UCSC:Q9NYM4 GPR83
Reference Transcript
RefSeq:NM_001330345.1 GPR83
RefSeq:NM_016540.3 GPR83
Other Identifiers
10888
11731824_at
11731825_at
16743367
222953_PM_at
222953_at
3387011
3387012
3387013
3387018
3387020
3387021
3387022
74906_at
7951040
A_24_P944131
GE82143
GO:0004930
GO:0004983
GO:0005886
GO:0005929
GO:0007165
GO:0007186
GO:0007200
GO:0007218
GO:0007631
GO:0008188
GO:0016020
GO:0023052
GO:0043226
GO:0051384
GO:0060089
GO:0097730
HMNXSV003041442
Hs.272385.0.S2_3p_at
ILMN_1740146
ILMN_2174341
PH_hs_0014064
TC11002198.hg
Participates
as a member of
Constitutively active orphan GPCRs [plasma membrane] (Homo sapiens)
Inferred To
gpr83.2 [plasma membrane]
(Xenopus tropicalis)
GPR83 [plasma membrane]
(Bos taurus)
GPR83 [plasma membrane]
(Canis familiaris)
GPR83 [plasma membrane]
(Gallus gallus)
GPR83 [plasma membrane]
(Sus scrofa)
Gpr83 [plasma membrane]
(Mus musculus)
Gpr83 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001317274.1
,
NP_057624.3
Guide to Pharmacology - Targets
119
OpenTargets
ENSG00000123901
HPA
ENSG00000123901-GPR83
GeneCards
Q9NYM4
Ensembl
ENST00000243673
,
ENSG00000123901
,
ENSP00000243673
,
ENST00000539203
,
ENSP00000441550
PRO
Q9NYM4
Pharos - Targets
Q9NYM4
HMDB Protein
HMDBP13634
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