AKT phosphorylates PHF20

Stable Identifier
R-HSA-6805785
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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AKT phosphorylates PHF20 on serine residue S291 (Park et al. 2012, Li et al. 2013), triggering PHF20 translocation to the cytosol (Park et al. 2012).

Literature References
PubMed ID Title Journal Year
22334668 Identification of Akt interaction protein PHF20/TZP that transcriptionally regulates p53

Park, S, Kim, D, Dan, HC, Chen, H, Testa, JR, Cheng, JQ

J. Biol. Chem. 2012
22975685 PKB-mediated PHF20 phosphorylation on Ser291 is required for p53 function in DNA damage

Li, Y, Park, J, Piao, L, Kong, G, Kim, Y, Park, KA, Zhang, T, Hong, J, Hur, GM, Seok, JH, Choi, SW, Yoo, BC, Hemmings, BA, Brazil, DP, Kim, SH, Park, J

Cell. Signal. 2013
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of p-T,p-S-AKT [nucleoplasm]
Physical Entity
Activity
Orthologous Events
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Created
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