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FAF2 [extracellular region]
Stable Identifier
R-HSA-6806183
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
FAS-associated factor 2, FAF2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [extracellular region] (Homo sapiens)
FAF2 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96CS3 FAF2
Gene Names
FAF2, ETEA, KIAA0887, UBXD8, UBXN3B
Chain
initiator methionine:, chain:2-445
Reference Genes
BioGPS Gene:23197 FAF2
COSMIC (genes):FAF2 FAF2
CTD Gene:23197 FAF2
dbSNP Gene:23197 FAF2
ENSEMBL:ENSG00000113194 FAF2
HGNC:24666 FAF2
KEGG:hsa:23197 FAF2
Monarch:23197 FAF2
NCBI Gene:23197 FAF2
OMIM:616935 FAF2
UCSC:Q96CS3 FAF2
Reference Transcript
RefSeq:NM_014613.2 FAF2
Other Identifiers
11716000_a_at
11716001_at
11716002_at
11716003_a_at
11716004_at
11753411_a_at
16992814
212106_PM_at
212106_at
212108_PM_at
212108_at
23197
2842569
2842571
2842572
2842573
2842574
2842575
2842576
2842581
2842582
2842583
2842585
2842586
2842587
2842589
2842590
2842594
2842597
2842598
2842601
2842602
2842603
2842605
2842606
2842610
2842611
2842612
2842613
2842614
37030_at
8110169
A_14_P119601
A_23_P156109
A_24_P294719
GE53562
GO:0005515
GO:0005576
GO:0005737
GO:0005783
GO:0005811
GO:0006886
GO:0006986
GO:0030163
GO:0030674
GO:0030970
GO:0031625
GO:0034098
GO:0034389
GO:0035473
GO:0035578
GO:0035617
GO:0036503
GO:0043130
GO:0043161
GO:0043226
GO:0055102
GO:0060090
GO:0098772
HMNXSV003046384
Hs.76591.0.S1_3p_at
Hs.76591.0.S2_3p_at
ILMN_1670472
PH_hs_0004422
TC05001000.hg
Participates
as a member of
Azurophil granule lumen proteins [extracellular region] (Homo sapiens)
Other forms of this molecule
FAF2 [cytosol]
FAF2 [azurophil granule lumen]
Inferred To
UBX2 [extracellular region]
(Saccharomyces cerevisiae)
ucp10 [extracellular region]
(Schizosaccharomyces pombe)
FAF2 [extracellular region]
(Bos taurus)
FAF2 [extracellular region]
(Caenorhabditis elegans)
FAF2 [extracellular region]
(Canis familiaris)
FAF2 [extracellular region]
(Dictyostelium discoideum)
FAF2 [extracellular region]
(Gallus gallus)
FAF2 [extracellular region]
(Plasmodium falciparum)
FAF2 [extracellular region]
(Sus scrofa)
Faf2 [extracellular region]
(Drosophila melanogaster)
Faf2 [extracellular region]
(Mus musculus)
Faf2 [extracellular region]
(Rattus norvegicus)
faf2 [extracellular region]
(Danio rerio)
faf2 [extracellular region]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENSP00000261942
,
ENST00000261942
OpenTargets
ENSG00000113194
HPA
ENSG00000113194-FAF2
PRO
Q96CS3
Pharos - Targets
Q96CS3
GlyGen
Q96CS3
PDB
2DAM
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P55072 VCP
8
VCP [cytosol]
(R-HSA-1181251)
VCP [secretory granule lumen]
(R-HSA-6801039)
VCP [extracellular region]
(R-HSA-6806191)
VCP [azurophil granule lumen]
(R-HSA-6800438)
VCP [ficolin-1-rich granule lumen]
(R-HSA-6800425)
VCP [nucleoplasm]
(R-HSA-5643745)
VCP [endoplasmic reticulum membrane]
(R-HSA-8943105)
Me3K315-VCP [cytosol]
(R-HSA-8932209)
0.826
14
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.706
17
UniProt:P40855 PEX19
1
PEX19 [cytosol]
(R-HSA-3009036)
0.643
4
UniProt:P0CG47 UBB
20
UBB(77-152) [endocytic vesicle membrane]
(R-HSA-939253)
UBB(1-76) [endocytic vesicle membrane]
(R-HSA-939231)
UBB(153-228) [endocytic vesicle membrane]
(R-HSA-939171)
Ub-33-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783023)
Ub-109-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783008)
Ub-185-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783046)
Ub-215-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783002)
Ub-63-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783148)
Ub-139-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783012)
Ub-158-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783162)
Ub-6-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783014)
Ub-82-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783015)
Ub-163-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783025)
Ub-87-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6782998)
Ub-11-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783109)
Ub-124-UBB(77-152) [mitochondrial outer membrane]
(R-HSA-6783131)
Ub-200-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783100)
Ub-48-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783165)
Ub-181-UBB(153-228) [mitochondrial outer membrane]
(R-HSA-6783160)
Ub-29-UBB(1-76) [mitochondrial outer membrane]
(R-HSA-6783070)
0.643
4
UniProt:P31350 RRM2
1
RRM2 [cytosol]
(R-HSA-73639)
0.527
2
UniProt:Q96JH7 VCPIP1
2
p-S131-VCPIP1 [endoplasmic reticulum lumen]
(R-HSA-8940104)
VCPIP1 [endoplasmic reticulum lumen]
(R-HSA-8940103)
0.527
2
UniProt:Q14534 SQLE
1
SQLE [endoplasmic reticulum membrane]
(R-HSA-191395)
0.527
2
UniProt:Q9NWR8 MCUB
1
MCUB [mitochondrial inner membrane]
(R-HSA-8949153)
0.527
2
UniProt:Q9BQ95 ECSIT
2
ECSIT [cytosol]
(R-HSA-168064)
ECSIT [mitochondrial inner membrane]
(R-HSA-5689047)
0.527
2
UniProt:Q9UBV2 SEL1L
1
SEL1L [endoplasmic reticulum membrane]
(R-HSA-1911545)
0.527
2
UniProt:Q03135 CAV1
5
CAV1 [Golgi membrane]
(R-HSA-204504)
CAV1 [plasma membrane]
(R-HSA-534994)
CAV1 [lipid droplet]
(R-HSA-163510)
CAV1 [endocytic vesicle membrane]
(R-HSA-535009)
CAV1 [early endosome membrane]
(R-HSA-5368451)
0.527
2
UniProt:Q96PK6 RBM14
1
RBM14 [nucleoplasm]
(R-HSA-8938345)
0.527
2
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