Reactome | CDK13 [extracellular region]

CDK13 [extracellular region]

Stable Identifier

R-HSA-6806442

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Cyclin-dependent kinase 13, CDC2-related protein kinase 5, Cholinesterase-related cell division controller, CDC2L, CDC2L5, CHED, KIAA1791

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14004 CDK13

Gene Names

CDK13, CDC2L, CDC2L5, CHED, KIAA1791

Chain

chain:1-1512

Reference Genes

BioGPS Gene:8621 CDK13

COSMIC (genes):CDK13 CDK13

CTD Gene:8621 CDK13

dbSNP Gene:8621 CDK13

ENSEMBL:ENSG00000065883 CDK13

ENSEMBL_homo_sapiens_GENE:ENSG00000065883.18 CDK13

HGNC:1733 CDK13

KEGG Gene (Homo sapiens):8621 CDK13

Monarch:8621 CDK13

NCBI Gene:8621 CDK13

OMIM:603309 CDK13

UCSC:Q14004 CDK13

Reference Transcript

Other Identifiers

11729002_a_at

11755318_s_at

17045404

1793_at

207318_PM_s_at

207318_s_at

207319_PM_s_at

207319_s_at

228991_PM_at

228991_at

2998543

2998544

2998545

2998546

2998547

2998548

2998549

2998550

2998551

2998552

2998553

2998564

2998565

2998566

2998567

2998568

2998572

2998576

2998577

2998588

2998590

2998599

2998600

2998613

2998614

2998615

2998617

2998618

2998619

2998621

2998622

2998623

2998625

2998626

2998627

41821_at

61726_at

71570_at

8132417

8621

A_14_P128114

A_14_P132583

A_14_P138420

A_23_P215296

A_24_P178493

A_33_P3329149

A_33_P3329153

GE58090

GO:0000166

GO:0000380

GO:0002945

GO:0003723

GO:0003824

GO:0004672

GO:0004674

GO:0004693

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005794

GO:0005829

GO:0006351

GO:0006355

GO:0006397

GO:0006468

GO:0008024

GO:0008353

GO:0008380

GO:0009966

GO:0016071

GO:0016301

GO:0016310

GO:0016607

GO:0016740

GO:0019901

GO:0019908

GO:0023052

GO:0030097

GO:0030154

GO:0030332

GO:0031410

GO:0032968

GO:0036211

GO:0043226

GO:0045944

GO:0048856

GO:0051726

GO:0106310

GO:0140096

GO:1904813

GO:2000737

HMNXSV003009600

Hs.36636.0.A1_3p_at

Hs.59498.0.S2_3p_a_at

ILMN_1778557

ILMN_2356068

M80629_at

PH_hs_0024632

TC07000254.hg

TC07002273.hg

TC07002274.hg

g4502710_3p_a_at

Participates

as a member of

Ficolin-rich granule lumen proteins [extracellular region] (Homo sapiens)

Other forms of this molecule

CDK13 [nucleoplasm]

CDK13 [ficolin-1-rich granule lumen]

Inferred To

CDK13 [extracellular region] (Bos taurus)

CDK13 [extracellular region] (Caenorhabditis elegans)

CDK13 [extracellular region] (Canis familiaris)

CDK13 [extracellular region] (Dictyostelium discoideum)

CDK13 [extracellular region] (Drosophila melanogaster)

CDK13 [extracellular region] (Gallus gallus)

CDK13 [extracellular region] (Mus musculus)

CDK13 [extracellular region] (Plasmodium falciparum)

CDK13 [extracellular region] (Rattus norvegicus)

CDK13 [extracellular region] (Saccharomyces cerevisiae)

CDK13 [extracellular region] (Schizosaccharomyces pombe)

CDK13 [extracellular region] (Sus scrofa)

CDK13 [extracellular region] (Xenopus tropicalis)

Homologues of CDK13 [extracellular region] (Dictyostelium discoideum)

Homologues of CDK13 [extracellular region] (Saccharomyces cerevisiae)

Homologues of CDK13 [extracellular region] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_003709.3, NP_112557.2

ZINC - World Drugs

CDK13_HUMAN

Guide to Pharmacology - Targets

1966

OpenTargets

ENSG00000065883

ZINC - Substances

CDK13_HUMAN

ZINC target

Q14004

ZINC - Biogenic

CDK13_HUMAN

PRO

Q14004

PDB

7NXJ, 5EFQ

ZINC - Investigational

CDK13_HUMAN

GeneCards

Q14004

HPA

ENSG00000065883-CDK13

Ensembl

ENSP00000340557, ENST00000340829, ENSP00000181839, ENSG00000065883, ENST00000181839

Pharos - Targets

Q14004

ZINC - Predictions - Purchasable

CDK13_HUMAN

Orphanet

25722

HMDB Protein

HMDBP01268

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75909 CCNK	1	CCNK [nucleoplasm] (R-HSA-6796619)	0.826	10
UniProt:Q16543 CDC37	1	CDC37 [cytosol] (R-HSA-1221609)	0.564	2
UniProt:P24941 CDK2	5	p-Y15-CDK2 [nucleoplasm] (R-HSA-187905) p-CDK2 [nucleoplasm] (R-HSA-68370) CDK2 [cytosol] (R-HSA-157440) CDK2 [nucleoplasm] (R-HSA-68365) p-T160-CDK2 [nucleoplasm] (R-HSA-187967)	0.527	2
UniProt:P08238 HSP90AB1	6	HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [lysosomal lumen] (R-HSA-9622846)	0.527	3
UniProt:P07900 HSP90AA1	8	HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [lysosomal lumen] (R-HSA-9622850)	0.527	3
UniProt:Q13451 FKBP5	2	FKBP5 [cytosol] (R-HSA-5618096) FKBP5 [nucleoplasm] (R-HSA-8939165)	0.527	3
UniProt:P11802 CDK4	3	CDK4 [cytosol] (R-HSA-68330) CDK4 [nucleoplasm] (R-HSA-113843) p-T172-CDK4 [nucleoplasm] (R-HSA-113830)	0.527	2
UniProt:Q07955 SRSF1	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.483	2

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