Reactome | PSMB7 [extracellular region]

PSMB7 [extracellular region]

Stable Identifier

R-HSA-6806449

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Proteasome subunit beta type 7, Proteasome subunit beta type 7 precursor , Proteasome subunit Z, Macropain chain Z, Multicatalytic endopeptidase complex chain Z

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q99436 PSMB7

Gene Names

PSMB7, Z

Chain

propeptide:1-43, chain:44-277

Reference Genes

BioGPS Gene:5695 PSMB7

COSMIC (genes):PSMB7 PSMB7

CTD Gene:5695 PSMB7

dbSNP Gene:5695 PSMB7

ENSEMBL:ENSG00000136930 PSMB7

ENSEMBL_homo_sapiens_GENE:ENSG00000136930.13 PSMB7

HGNC:9544 PSMB7

KEGG Gene (Homo sapiens):5695 PSMB7

Monarch:5695 PSMB7

NCBI Gene:5695 PSMB7

OMIM:604030 PSMB7

UCSC:Q99436 PSMB7

Reference Transcript

RefSeq:NM_002799.3 PSMB7

Other Identifiers

11715595_a_at

11715596_at

11715597_x_at

1313_at

17098278

200786_PM_at

200786_at

3225004

3225005

3225006

3225014

3225037

3225043

3225045

3225046

3225047

3225050

39060_at

5695

8164067

A_23_P9362

D38048_at

GE57182

GO:0000502

GO:0003824

GO:0004175

GO:0004298

GO:0005515

GO:0005576

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005839

GO:0006508

GO:0008233

GO:0010498

GO:0016604

GO:0016787

GO:0019774

GO:0030163

GO:0031410

GO:0034774

GO:0043161

GO:0043226

GO:0051603

GO:0140096

GO:1904813

HMNXSV003047663

ILMN_1814156

PH_hs_0022957

TC09001578.hg

g4506202_3p_at

Participates

as a member of

Other forms of this molecule

PSMB7(1-43) [cytosol]

pro-PSMB7 [cytosol]

PSMB7 [secretory granule lumen]

PSMB7 [ficolin-1-rich granule lumen]

PSMB7 [nucleoplasm]

PSMB7 [cytosol]

Inferred To

PSMB7 [extracellular region] (Bos taurus)

PSMB7 [extracellular region] (Canis familiaris)

PSMB7 [extracellular region] (Plasmodium falciparum)

PSMB7 [extracellular region] (Sus scrofa)

Psmb7 [extracellular region] (Mus musculus)

Psmb7 [extracellular region] (Rattus norvegicus)

Prosbeta2 [extracellular region] (Drosophila melanogaster)

cpsmb7 [extracellular region] (Gallus gallus)

PUP1 [extracellular region] (Saccharomyces cerevisiae)

pbs-2 [extracellular region] (Caenorhabditis elegans)

psmb13a [extracellular region] (Danio rerio)

pup1 [extracellular region] (Schizosaccharomyces pombe)

psmB7 [extracellular region] (Dictyostelium discoideum)

Cross References

RefSeq

NP_002790.1

OpenTargets

ENSG00000136930

GeneCards

Q99436

HPA

ENSG00000136930-PSMB7

ZINC target

Q99436

Ensembl

ENSP00000259457, ENST00000259457, ENSG00000136930

PRO

Q99436

Pharos - Targets

Q99436

PDB

5T0H, 4R67, 6XMJ, 7W3A, 6RGQ, 8UD9, 5GJQ, 5GJR, 7QXU, 6REY, 5T0G, 6HUB, 7W38, 7W3I, 8CVT, 7QYB, 7QXP, 8QZ9, 5VFQ, 5LEZ, 5LF0, 7QXN, 8BZL, 7QXW, 5A0Q, 5VFO, 6HUQ, 6WJD, 7W3K, 5VFU, 5LF6, 5LN3, 6HTD, 7V5M, 7NAQ, 5VFS, 6MSB, 4R3O, 6KWY, 5LF3, 8QYN, 5M32, 7PG9, 6HTB, 7W3H, 8CVR, 7NAP, 8QYJ, 6R70, 7QXX, 7NAO, 7W3F, 5LE5, 7NAN, 7W3B, 5L4G, 5T0I, 6MSK, 5T0C, 7W3J, 7W39, 5VFR, 8QYS, 6WJN, 8CVS, 8CXB, 7W37, 6HTR, 5LF1, 5VFP, 8QYL, 6HUV, 7NHT, 7QY7, 6MSG, 5LEY, 7W3M, 7LXV, 6HTP, 6MSE, 5LF7, 6MSD, 6HUC, 6MSJ, 5LEX, 5LF4, 7QYA, 8QYO, 6HTC, 5VFT, 6MSH, 7W3G, 7V5G, 5T0J, 8QYM, 6HUU, 7W3C

Interactors (35)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25786 PSMA1	2	PSMA1 [nucleoplasm] (R-HSA-174333) PSMA1 [cytosol] (R-HSA-68724)	0.862	13
UniProt:P20618 PSMB1	7	PSMB1(1-28) [cytosol] (R-HSA-9908143) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) PSMB1 [nucleoplasm] (R-HSA-174347) PSMB1 [cytosol] (R-HSA-68738)	0.85	13
UniProt:Q9Y244 POMP	1	POMP [cytosol] (R-HSA-9908067)	0.804	6
UniProt:P28074 PSMB5	4	PSMB5(1-59) [cytosol] (R-HSA-9908134) pro-PSMB5 [cytosol] (R-HSA-9908135) PSMB5 [nucleoplasm] (R-HSA-174344) PSMB5 [cytosol] (R-HSA-68753)	0.804	10
UniProt:P28065 PSMB9	3	PSMB9(1-20) [cytosol] (R-HSA-9908132) PSMB9 [cytosol] (R-HSA-68765) pro-PSMB9 [cytosol] (R-HSA-9908136)	0.798	10
UniProt:P25787 PSMA2	5	PSMA2 [secretory granule lumen] (R-HSA-6803329) PSMA2 [extracellular region] (R-HSA-6806506) PSMA2 [ficolin-1-rich granule lumen] (R-HSA-6803285) PSMA2 [nucleoplasm] (R-HSA-174345) PSMA2 [cytosol] (R-HSA-68726)	0.788	8
UniProt:P28072 PSMB6	4	PSMB6(1-34) [cytosol] (R-HSA-9908141) pro-PSMB6 [cytosol] (R-HSA-9908130) PSMB6 [nucleoplasm] (R-HSA-174342) PSMB6 [cytosol] (R-HSA-68756)	0.745	5
UniProt:P49720 PSMB3	2	PSMB3 [nucleoplasm] (R-HSA-174341) PSMB3 [cytosol] (R-HSA-68747)	0.738	6
UniProt:P49721 PSMB2	2	PSMB2 [nucleoplasm] (R-HSA-174335) PSMB2 [cytosol] (R-HSA-68744)	0.725	9
UniProt:Q15008 PSMD6	5	PSMD6 [secretory granule lumen] (R-HSA-6801036) PSMD6 [extracellular region] (R-HSA-6806486) PSMD6 [ficolin-1-rich granule lumen] (R-HSA-6800440) PSMD6 [nucleoplasm] (R-HSA-174316) PSMD6 [cytosol] (R-HSA-68804)	0.669	3
UniProt:P28070 PSMB4	4	PSMB4(1-45) [cytosol] (R-HSA-9908122) pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4 [nucleoplasm] (R-HSA-174343) PSMB4 [cytosol] (R-HSA-68750)	0.659	4
UniProt:Q06323 PSME1	1	PSME1 [cytosol] (R-HSA-68812)	0.643	4
UniProt:O14818 PSMA7	2	PSMA7 [nucleoplasm] (R-HSA-174351) PSMA7 [cytosol] (R-HSA-68736)	0.643	4
UniProt:P28066 PSMA5	5	PSMA5 [secretory granule lumen] (R-HSA-6803316) PSMA5 [extracellular region] (R-HSA-6806459) PSMA5 [ficolin-1-rich granule lumen] (R-HSA-6803328) PSMA5 [nucleoplasm] (R-HSA-174340) PSMA5 [cytosol] (R-HSA-68732)	0.643	5
UniProt:P60900 PSMA6	2	PSMA6 [nucleoplasm] (R-HSA-174314) PSMA6 [cytosol] (R-HSA-68734)	0.643	4
UniProt:Q9Y5K5 UCHL5	2	UCHL5 [cytosol] (R-HSA-1629778) UCHL5 [nucleoplasm] (R-HSA-5689584)	0.643	3
UniProt:P25789 PSMA4	2	PSMA4 [nucleoplasm] (R-HSA-174324) PSMA4 [cytosol] (R-HSA-68730)	0.643	9
UniProt:Q14997 PSME4	1	PSME4 [cytosol] (R-HSA-947606)	0.643	4
UniProt:O00231 PSMD11	5	PSMD11 [secretory granule lumen] (R-HSA-6800943) PSMD11 [extracellular region] (R-HSA-6806441) PSMD11 [ficolin-1-rich granule lumen] (R-HSA-6800436) PSMD11 [nucleoplasm] (R-HSA-174327) PSMD11 [cytosol] (R-HSA-68790)	0.643	3
UniProt:P62333 PSMC6	2	PSMC6 [nucleoplasm] (R-HSA-174319) PSMC6 [cytosol] (R-HSA-68783)	0.638	3
UniProt:P55036 PSMD4	1	PSMD4 [cytosol] (R-HSA-68800)	0.564	3
UniProt:Q99436 PSMB7	7	PSMB7(1-43) [cytosol] (R-HSA-9908129) pro-PSMB7 [cytosol] (R-HSA-9908145) PSMB7 [secretory granule lumen] (R-HSA-6803279) PSMB7 [extracellular region] (R-HSA-6806449) PSMB7 [ficolin-1-rich granule lumen] (R-HSA-6803312) PSMB7 [nucleoplasm] (R-HSA-174331) PSMB7 [cytosol] (R-HSA-68759)	0.553	2
UniProt:Q9Y3I1 FBXO7	1	FBXO7 [cytosol] (R-HSA-8862627)	0.527	3
UniProt:Q9GZU8 PIP30			0.527	2
UniProt:Q92530 PSMF1	1	PSMF1 [cytosol] (R-HSA-68818)	0.527	3
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.527	4
UniProt:Q5VYK3 ECM29			0.527	2
UniProt:P43686 PSMC4	2	PSMC4 [nucleoplasm] (R-HSA-174315) PSMC4 [cytosol] (R-HSA-68777)	0.527	3
UniProt:O95456 PSMG1	1	PSMG1 [cytosol] (R-HSA-9908050)	0.527	4
UniProt:Q969U7 PSMG2	1	PSMG2 [cytosol] (R-HSA-9908053)	0.527	3
UniProt:Q9BT73 PSMG3	1	PSMG3 [cytosol] (R-HSA-9908033)	0.527	3
UniProt:P61289 PSME3	1	PSME3 [cytosol] (R-HSA-68816)	0.527	2
UniProt:P28062 PSMB8	4	PSMB8(1-72) [cytosol] (R-HSA-9908131) PSMB8 [cytosol] (R-HSA-68762) pro-PSMB8 [cytosol] (R-HSA-9908127) PSMB8 [nucleoplasm] (R-HSA-174336)	0.527	6
UniProt:Q9UL46 PSME2	2	PSME2 [nucleoplasm] (R-HSA-174350) PSME2 [cytosol] (R-HSA-68814)	0.527	3
UniProt:O43242 PSMD3	5	PSMD3 [secretory granule lumen] (R-HSA-6800873) PSMD3 [extracellular region] (R-HSA-6806443) PSMD3 [ficolin-1-rich granule lumen] (R-HSA-6800408) PSMD3 [nucleoplasm] (R-HSA-174328) PSMD3 [cytosol] (R-HSA-68798)	0.527	3

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