Reactome | ATG7 [extracellular region]

ATG7 [extracellular region]

Stable Identifier

R-HSA-6806451

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Autophagy-related protein 7, ATG7_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O95352 ATG7

Gene Names

ATG7, APG7L

Chain

initiator methionine:, chain:2-703

Reference Genes

BioGPS Gene:10533 ATG7

COSMIC (genes):ATG7 ATG7

CTD Gene:10533 ATG7

dbSNP Gene:10533 ATG7

ENSEMBL:ENSG00000197548 ATG7

ENSEMBL_homo_sapiens_GENE:ENSG00000197548.13 ATG7

HGNC:16935 ATG7

KEGG Gene (Homo sapiens):10533 ATG7

Monarch:10533 ATG7

NCBI Gene:10533 ATG7

OMIM:608760 ATG7

UCSC:O95352 ATG7

Reference Transcript

Other Identifiers

10533

11727027_a_at

11740814_a_at

11750782_a_at

16937681

218673_PM_s_at

218673_s_at

222709_PM_at

222709_at

224025_PM_s_at

224025_s_at

2610733

2610735

2610736

2610737

2610738

2610742

2610743

2610746

2610749

2610750

2610752

2610756

2610758

2610759

2610761

2610762

2610764

2610771

2610772

2610773

2610774

2610777

2610784

2610831

2610832

2610833

2610834

2610835

2610836

2610837

2610838

2610839

2610840

2610841

2610842

2610843

2610844

44129_at

8077858

A_14_P105554

A_14_P200647

A_23_P143987

A_24_P944827

GE62471

GO:0000045

GO:0000407

GO:0000423

GO:0003824

GO:0005515

GO:0005576

GO:0005737

GO:0005829

GO:0005856

GO:0005929

GO:0005930

GO:0006497

GO:0006914

GO:0006995

GO:0007005

GO:0008641

GO:0009267

GO:0012501

GO:0015031

GO:0016236

GO:0016874

GO:0019778

GO:0019779

GO:0030163

GO:0031401

GO:0031410

GO:0032446

GO:0034727

GO:0034774

GO:0036211

GO:0042752

GO:0042803

GO:0043065

GO:0043226

GO:0044804

GO:0045732

GO:0048511

GO:0051607

GO:0071455

GO:0098542

GO:0140096

GO:0140657

GO:1904813

HMNXSV003043302

HMNXSV003057907

Hs.278607.0.S2_3p_at

ILMN_1790978

PH_hs_0014291

TC03000065.hg

g5453667_3p_a_at

Participates

as a member of

Other forms of this molecule

ATG7 [secretory granule lumen]

ATG7 [ficolin-1-rich granule lumen]

ATG7(1-693)-BRAF(381-766) fusion [cytosol]

ATG7(1-693)-p-BRAF(381-766) fusion [cytosol]

CysO572-ATG7-MAP1LC3B [cytosol]

CysO572-ATG7-GARABAPL2 [cytosol]

CysO572-ATG7-GARABAP [cytosol]

CysO572-ATG7-GARABAPL1 [cytosol]

CysO572-ATG7-MAP1LC3C [cytosol]

CysO572-ATG7-MAP1LC3A [cytosol]

CysO572-ATG7-GARABAPL3 [cytosol]

CysO572-ATG7 [cytosol]

ATG7 [cytosol]

Inferred To

atg-7 [extracellular region] (Caenorhabditis elegans)

ATG7 [extracellular region] (Bos taurus)

ATG7 [extracellular region] (Canis familiaris)

ATG7 [extracellular region] (Gallus gallus)

ATG7 [extracellular region] (Plasmodium falciparum)

ATG7 [extracellular region] (Saccharomyces cerevisiae)

ATG7 [extracellular region] (Sus scrofa)

atg7 [extracellular region] (Dictyostelium discoideum)

atg7 [extracellular region] (Schizosaccharomyces pombe)

atg7 [extracellular region] (Xenopus tropicalis)

Atg7 [extracellular region] (Drosophila melanogaster)

Atg7 [extracellular region] (Mus musculus)

Atg7 [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_001138384.1, XP_011531584.1, NP_006386.1, XP_016861034.1, XP_016861035.1, XP_011531588.1, XP_016861033.1, NP_001129503.2

OpenTargets

ENSG00000197548

GeneCards

O95352

HPA

ENSG00000197548-ATG7

ZINC target

O95352

Ensembl

ENSP00000510336, ENSP00000412580, ENSP00000509725, ENSP00000347042, ENST00000446450, ENST00000685771, ENSG00000197548, ENST00000693202, ENSP00000346437, ENST00000354956, ENST00000354449

PRO

O95352

Pharos - Targets

O95352

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9GZQ8 MAP1LC3B	3	MAP1LC3B [autophagosome membrane] (R-HSA-5683641) MAP1LC3B(2-121) [cytosol] (R-HSA-5682674) MAP1LC3B [cytosol] (R-HSA-5205651)	0.743	7
UniProt:Q9H0Y0 ATG10	2	GlyK166-ATG10 [cytosol] (R-HSA-5683572) ATG10 [cytosol] (R-HSA-5671733)	0.643	3
UniProt:Q96EB6 SIRT1	1	SIRT1 [nucleoplasm] (R-HSA-427531)	0.602	3
UniProt:Q9NT62 ATG3	8	ATG3 [cytosol] (R-HSA-5671860) CysO264-ATG3-MAP1LC3A [cytosol] (R-HSA-9819371) CysO264-ATG3-GABARAP [cytosol] (R-HSA-9819379) CysO264-ATG3-GABARAPL3 [cytosol] (R-HSA-5683569) CysO264-ATG3-MAP1LC3B [cytosol] (R-HSA-9819365) CysO264-ATG3-GABARAPL1 [cytosol] (R-HSA-9819381) CysO264-ATG3-MAP1LC3C [cytosol] (R-HSA-9819377) CysO264-ATG3-GABARAPL2 [cytosol] (R-HSA-9819376)	0.527	4
UniProt:Q5VWX1 KHDRBS2	2	KHDRBS2 [nucleoplasm] (R-HSA-8849028) p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031)	0.527	2
UniProt:Q99538 LGMN	2	LGMN [lysosomal lumen] (R-HSA-350135) LGMN [endolysosome lumen] (R-HSA-8942384)	0.527	2
UniProt:P29692 EEF1D	1	EEF1D [cytosol] (R-HSA-156914)	0.524	2
UniProt:P14316 IRF2	2	IRF2 [cytosol] (R-HSA-1015681) IRF2 [nucleoplasm] (R-HSA-994031)	0.499	2

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