Reactome | PSMA5 [extracellular region]

PSMA5 [extracellular region]

Stable Identifier

R-HSA-6806459

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Proteasome subunit alpha type 5 , Proteasome zeta chain, Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P28066 PSMA5

Gene Names

PSMA5

Chain

chain:1-241

Reference Genes

BioGPS Gene:5686 PSMA5

COSMIC (genes):PSMA5 PSMA5

CTD Gene:5686 PSMA5

dbSNP Gene:5686 PSMA5

ENSEMBL:ENSG00000143106 PSMA5

ENSEMBL:ENSG00000143106.13 PSMA5

HGNC:9534 PSMA5

KEGG Gene (Homo sapiens):5686 PSMA5

Monarch:5686 PSMA5

NCBI Gene:5686 PSMA5

OMIM:176844 PSMA5

UCSC:P28066 PSMA5

Reference Transcript

Other Identifiers

11715668_a_at

16690594

201274_PM_at

201274_at

230300_PM_at

230300_at

2427066

2427067

2427068

2427069

2427070

2427071

2427072

2427073

2427075

2427076

2427077

2427078

2427079

2427080

2427088

2427090

2427091

2427092

2427095

2427097

2427098

2427102

2427103

2427104

2427105

2427106

2427107

37046_at

5686

61368_at

73310_at

7918345

A_23_P86216

GE59874

GE824853

GO:0000502

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005839

GO:0006511

GO:0019773

GO:0030163

GO:0031410

GO:0034774

GO:0043161

GO:0043226

GO:0051603

GO:0070062

GO:1904813

HMNXSV003024721

Hs.26037.0.A1_3p_at

ILMN_1759952

PH_hs_0002295

PH_hs_0004438

TC01002955.hg

TC01005688.hg

X61970_at

g4506186_3p_s_at

Participates

as a member of

Other forms of this molecule

PSMA5 [secretory granule lumen]

PSMA5 [ficolin-1-rich granule lumen]

PSMA5 [nucleoplasm]

PSMA5 [cytosol]

Inferred To

pup2 [extracellular region] (Schizosaccharomyces pombe)

Psma5 [extracellular region] (Mus musculus)

Psma5 [extracellular region] (Rattus norvegicus)

psma5 [extracellular region] (Xenopus tropicalis)

Prosalpha5 [extracellular region] (Drosophila melanogaster)

psmA5 [extracellular region] (Dictyostelium discoideum)

PUP2 [extracellular region] (Saccharomyces cerevisiae)

pas-5 [extracellular region] (Caenorhabditis elegans)

PSMA5 [extracellular region] (Bos taurus)

PSMA5 [extracellular region] (Canis familiaris)

PSMA5 [extracellular region] (Danio rerio)

PSMA5 [extracellular region] (Gallus gallus)

PSMA5 [extracellular region] (Plasmodium falciparum)

PSMA5 [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_001186703.1, NP_001186701.1, NP_001186702.1, NP_002781.2

OpenTargets

ENSG00000143106

GeneCards

P28066

HPA

ENSG00000143106-PSMA5

Ensembl

ENST00000271308, ENSG00000143106, ENSP00000271308, ENSP00000440618, ENST00000538610

PRO

P28066

Pharos - Targets

P28066

PDB

4R67, 5LF4, 5L4G, 5LF3, 7W3A, 5A0Q, 7QXN, 5VFS, 5GJR, 5LEX, 7QXP, 7W3I, 7W3H, 5VFQ, 6MSB, 7QXW, 7QXX, 5T0I, 7NAN, 5VFP, 7AWE, 7QY7, 5VFT, 5T0H, 7NAO, 7LXV, 6KWY, 7W38, 7W39, 5T0G, 7NAP, 6MSG, 6MSH, 7NAQ, 5T0C, 5LE5, 6WJD, 6MSJ, 7W3B, 6MSK, 7B12, 8CVR, 4R3O, 5LF1, 7W3C, 8CXB, 5LEZ, 6WJN, 5LEY, 5LF0, 6R70, 7W3F, 8CVS, 7W3G, 7NHT, 8CVT, 5VFR, 5GJQ, 7QXU, 7PG9, 5T0J, 6RGQ, 7W3J, 6MSD, 6AVO, 6MSE, 6E5B, 6REY, 7V5G, 6XMJ, 5VFO, 7W37, 5VFU, 5LF7, 7W3K, 7QYA, 5LF6, 5LN3, 7QYB, 5M32, 7V5M, 7W3M

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y5K5 UCHL5	2	UCHL5 [nucleoplasm] (R-HSA-5689584) UCHL5 [cytosol] (R-HSA-1629778)	0.527	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P62333 PSMC6	2	PSMC6 [nucleoplasm] (R-HSA-174319) PSMC6 [cytosol] (R-HSA-68783)	0.495	2

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