Reactome | SRP14 [extracellular region]

SRP14 [extracellular region]

Stable Identifier

R-HSA-6806495

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P37108 SRP14

Gene Names

SRP14

Chain

initiator methionine:, chain:2-136

Reference Genes

BioGPS Gene:6727 SRP14

COSMIC (genes):SRP14 SRP14

CTD Gene:6727 SRP14

dbSNP Gene:6727 SRP14

ENSEMBL:ENSG00000140319 SRP14

HGNC:11299 SRP14

KEGG:hsa:6727 SRP14

Monarch:6727 SRP14

NCBI Gene:6727 SRP14

OMIM:600708 SRP14

UCSC:P37108 SRP14

Reference Transcript

RefSeq:NM_003134.5 SRP14

Other Identifiers

11718663_s_at

11757592_x_at

16653261

16807308

18671434

18671435

18671436

18671437

18671438

18671439

18671440

18671441

18671442

18671443

18671444

200007_PM_at

200007_at

3344777

3619167

3619168

3619169

3619170

3619171

3619172

3619173

3619174

3619175

3619176

3619177

3619178

3619179

3619180

3619181

3619197

3619199

41194_at

6727

7893374

7894174

7894372

7894757

7895752

7896068

7896159

7896524

7987449

A_23_P14876

A_32_P200773

GE81240

GE87597

GO:0003723

GO:0005515

GO:0005576

GO:0005634

GO:0005737

GO:0005786

GO:0005829

GO:0006613

GO:0006614

GO:0008312

GO:0030942

GO:0034774

GO:0043226

GO:0045047

GO:0048500

GO:1904813

HMNXSV003028400

ILMN_1809347

ILMN_2234758

PH_hs_0027285

TC15001228.hg

U07857_at

g4507210_3p_at

Participates

as a member of

Other forms of this molecule

SRP14 [cytosol]

SRP14 [ficolin-1-rich granule lumen]

SRP14 [secretory granule lumen]

Inferred To

srp14-1 [extracellular region] (Dictyostelium discoideum)

SRP14 [extracellular region] (Bos taurus)

SRP14 [extracellular region] (Caenorhabditis elegans)

SRP14 [extracellular region] (Canis familiaris)

SRP14 [extracellular region] (Gallus gallus)

SRP14 [extracellular region] (Plasmodium falciparum)

SRP14 [extracellular region] (Saccharomyces cerevisiae)

SRP14 [extracellular region] (Sus scrofa)

Srp14 [extracellular region] (Drosophila melanogaster)

Srp14 [extracellular region] (Mus musculus)

Srp14 [extracellular region] (Rattus norvegicus)

srp14 [extracellular region] (Danio rerio)

srp14 [extracellular region] (Schizosaccharomyces pombe)

srp14 [extracellular region] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000267884, ENSP00000267884

OpenTargets

ENSG00000140319

HPA

ENSG00000140319-SRP14

PRO

P37108

Pharos - Targets

P37108

GlyGen

P37108

PDB

4UYJ, 4UYK, 7NFX, 5AOX, 1E8O, 1E8S, 1RY1

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.615	12
UniProt:P67809 YBX1	5	p-S32,S36-YBX1 [nucleoplasm] (R-HSA-9733227) p-S32,S36-YBX1 [cytosol] (R-HSA-9736837) YBX1 [cytosol] (R-HSA-9736840) YBX1 [nucleoplasm] (R-HSA-72041) YBX1 [extracellular region] (R-HSA-9017791)	0.564	2
UniProt:Q96JC9 EAF1	1	EAF1 [nucleoplasm] (R-HSA-8932787)	0.556	3
UniProt:P05388 RPLP0	1	RPLP0 [cytosol] (R-HSA-72396)	0.527	2
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.527	6

Cite Us!