Reactome | CAND1 [extracellular region]

CAND1 [extracellular region]

Stable Identifier

R-HSA-6806498

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Cullin-associated NEDD8-dissociated protein 1, CAND1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q86VP6 CAND1

Gene Names

CAND1, KIAA0829, TIP120, TIP120A

Chain

initiator methionine:, chain:2-1230

Reference Genes

BioGPS Gene:55832 CAND1

COSMIC (genes):CAND1 CAND1

CTD Gene:55832 CAND1

dbSNP Gene:55832 CAND1

ENSEMBL:ENSG00000111530 CAND1

ENSEMBL_homo_sapiens_GENE:ENSG00000111530.13 CAND1

HGNC:30688 CAND1

KEGG Gene (Homo sapiens):55832 CAND1

Monarch:55832 CAND1

NCBI Gene:55832 CAND1

OMIM:607727 CAND1

UCSC:Q86VP6 CAND1

Reference Transcript

RefSeq:NM_018448.4 CAND1

Other Identifiers

11719937_a_at

11719938_s_at

11719939_a_at

16753712

207483_PM_s_at

207483_s_at

208838_PM_at

208838_at

208839_PM_s_at

208839_s_at

235224_PM_s_at

235224_s_at

243910_PM_x_at

243910_x_at

32196_at

3420716

3420717

3420718

3420719

3420720

3420721

3420727

3420734

3420736

3420737

3420738

3420739

3420740

3420741

3420742

3420744

3420745

3420746

3420747

3420750

3420753

3420754

3420755

3420757

3420758

3420759

3420760

3420761

3420762

3420764

3420766

3420768

3420770

3420772

3420774

55832

59523_at

7956910

86969_at

88937_at

A_14_P135815

A_23_P25137

A_23_P25141

A_24_P47681

A_32_P150418

A_32_P232237

GE62226

GE82377

GE893252

GO:0000151

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005794

GO:0005829

GO:0006351

GO:0006355

GO:0010265

GO:0016020

GO:0016567

GO:0017025

GO:0030154

GO:0031410

GO:0031461

GO:0034774

GO:0036211

GO:0043086

GO:0043226

GO:0045893

GO:0045899

GO:0065003

GO:0070062

GO:1904813

HMNXSV003013627

HMNXSV003015307

Hs.128521.0.S1_3p_at

Hs.209521.0.A1_3p_at

ILMN_1744647

PH_hs_0026787

TC12000595.hg

TC12002426.hg

g12053130_3p_a_at

g8924259_3p_s_at

Participates

as a member of

Other forms of this molecule

CAND1 [cytosol]

CAND1 [ficolin-1-rich granule lumen]

CAND1 [secretory granule lumen]

CAND1 [nucleoplasm]

Inferred To

Homologues of CAND1 [extracellular region] (Schizosaccharomyces pombe)

CAND1 [extracellular region] (Bos taurus)

CAND1 [extracellular region] (Canis familiaris)

CAND1 [extracellular region] (Gallus gallus)

CAND1 [extracellular region] (Schizosaccharomyces pombe)

CAND1 [extracellular region] (Sus scrofa)

cand-1 [extracellular region] (Caenorhabditis elegans)

Cand1 [extracellular region] (Drosophila melanogaster)

Cand1 [extracellular region] (Mus musculus)

Cand1 [extracellular region] (Rattus norvegicus)

cand1 [extracellular region] (Danio rerio)

cand1 [extracellular region] (Dictyostelium discoideum)

cand1 [extracellular region] (Xenopus tropicalis)

knd1 [extracellular region] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_060918.2

OpenTargets

ENSG00000111530

GeneCards

Q86VP6

HPA

ENSG00000111530-CAND1

Ensembl

ENSP00000442318, ENSG00000111530, ENST00000545606

PRO

Q86VP6

Pharos - Targets

Q86VP6

PDB

8OR2, 8CDJ, 7ZBZ, 8CDK, 1U6G, 8OR3, 7Z8R, 8H3Q, 4A0C, 8OR4, 7Z8T, 8OR0, 7ZBW, 7Z8V

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13616 CUL1	3	G76-NEDD8-K720-CUL1 [cytosol] (R-HSA-8952519) CUL1 [nucleoplasm] (R-HSA-187551) CUL1 [cytosol] (R-HSA-174230)	0.956	33
UniProt:Q13620 CUL4B	2	CUL4B [nucleoplasm] (R-HSA-975973) G76-NEDD8-K859-CUL4B [nucleoplasm] (R-HSA-8952522)	0.793	13
UniProt:Q13618 CUL3	3	G76-NEDD8-K712-CUL3 [cytosol] (R-HSA-8952516) CUL3 [nucleoplasm] (R-HSA-5635033) CUL3 [cytosol] (R-HSA-975979)	0.748	8
UniProt:Q13619 CUL4A	2	CUL4A [nucleoplasm] (R-HSA-976006) G76-NEDD8-K705-CUL4A [nucleoplasm] (R-HSA-8952514)	0.723	6
UniProt:P62877 RBX1	2	RBX1 [nucleoplasm] (R-HSA-1234142) RBX1 [cytosol] (R-HSA-180582)	0.708	10
UniProt:Q13617 CUL2	3	G76-NEDD8-K689-CUL2 [cytosol] (R-HSA-8952511) CUL2 [nucleoplasm] (R-HSA-1234126) CUL2 [cytosol] (R-HSA-416982)	0.641	3
UniProt:P46776 RPL27A	3	3OHH39-RPL27A [nucleoplasm] (R-HSA-9630970) RPL27A [nucleoplasm] (R-HSA-9630984) RPL27A [cytosol] (R-HSA-72442)	0.564	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:Q93034 CUL5	2	CUL5 [cytosol] (R-HSA-180528) G76-NEDD8-K724-CUL5 [cytosol] (R-HSA-8952014)	0.527	9
UniProt:Q92804 TAF15	1	TAF15 [nucleoplasm] (R-HSA-9020680)	0.483	2
ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE			0.462	2
ChEBI:18348 1-PHOSPHATIDYL-1D-MYO-INOSITOL 4,5-BISPHOSPHATE			0.462	2

Cite Us!