Reactome | DYNLT1 [extracellular region]

DYNLT1 [extracellular region]

Stable Identifier

R-HSA-6806509

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Dynein light chain Tctex-type 1, DYLT1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P63172 DYNLT1

Gene Names

DYNLT1, TCTEL1, TCTEX-1, TCTEX1

Chain

chain:1-113

Reference Genes

BioGPS Gene:6993 DYNLT1

COSMIC (genes):DYNLT1 DYNLT1

CTD Gene:6993 DYNLT1

dbSNP Gene:6993 DYNLT1

ENSEMBL:ENSG00000146425 DYNLT1

HGNC:11697 DYNLT1

KEGG:hsa:6993 DYNLT1

Monarch:6993 DYNLT1

NCBI Gene:6993 DYNLT1

OMIM:601554 DYNLT1

UCSC:P63172 DYNLT1

Reference Transcript

RefSeq:NM_006519.4 DYNLT1

Other Identifiers

11716583_a_at

11716584_x_at

11753785_x_at

17025177

201999_PM_s_at

201999_s_at

2981875

2981876

2981877

2981878

2981879

2981880

2981881

2981882

2981885

2981886

2981889

2981890

3710718

6993

8130499

946_at

A_23_P8185

A_33_P3260445

D50663_at

GE61149

GO:0000132

GO:0005515

GO:0005576

GO:0005737

GO:0005794

GO:0005819

GO:0005856

GO:0005868

GO:0005874

GO:0005881

GO:0007010

GO:0007018

GO:0007399

GO:0008277

GO:0019060

GO:0030286

GO:0032388

GO:0034774

GO:0042802

GO:0043226

GO:0043657

GO:0045505

GO:0046718

GO:0048856

GO:0050768

GO:0051301

GO:0075521

GO:0075606

GO:0099503

GO:1904813

HMNXSV003011447

HMNXSV003016472

ILMN_1678766

PH_hs_0013701

TC06002263.hg

g5730084_3p_a_at

Participates

as a member of

Other forms of this molecule

DYNLT1 [secretory granule lumen]

DYNLT1 [ficolin-1-rich granule lumen]

DYNLT1 [cytosol]

Inferred To

DYNLT1 [extracellular region] (Bos taurus)

DYNLT1 [extracellular region] (Canis familiaris)

DYNLT1 [extracellular region] (Gallus gallus)

DYNLT1 [extracellular region] (Plasmodium falciparum)

DYNLT1 [extracellular region] (Sus scrofa)

LOC101902787 [extracellular region] (Bos taurus)

dlcA [extracellular region] (Dictyostelium discoideum)

Homologues of DYNLT1 [extracellular region] (Bos taurus)

Dlc90F [extracellular region] (Drosophila melanogaster)

dynlt1 [extracellular region] (Xenopus tropicalis)

dynlt1b [extracellular region] (Danio rerio)

Dynlt1 [extracellular region] (Mus musculus)

Dynlt1 [extracellular region] (Rattus norvegicus)

dlc1 [extracellular region] (Schizosaccharomyces pombe)

dylt-1 [extracellular region] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006510.1

OpenTargets

ENSG00000146425

ENSEMBL

ENST00000367089, ENSG00000146425, ENSP00000356056

GeneCards

DYNLT1

HPA

ENSG00000146425-DYNLT1

PRO

P63172

Pharos - Targets

P63172

GlyGen

P63172

PDB

8PR0, 8J07, 8PTK, 5JPW, 8PR1, 8RGI

Interactors (45)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13409 DYNC1I2	1	DYNC1I2 [cytosol] (R-HSA-201607)	0.805	6
UniProt:Q8WW35 DYNLT2B	2	DYNLT2B [ciliary tip] (R-HSA-5625403) DYNLT2B [cilium] (R-HSA-5624893)	0.793	7
UniProt:P51808 DYLT3			0.731	5
UniProt:Q9Y6G9 DYNC1LI1	4	DYNC1LI1 [secretory granule membrane] (R-HSA-6801371) DYNC1LI1 [plasma membrane] (R-HSA-6801598) DYNC1LI1 [ficolin-1-rich granule membrane] (R-HSA-6801381) DYNC1LI1 [cytosol] (R-HSA-8943213)	0.725	4
UniProt:P63167 DYNLL1	6	DYNLL1 [cytosol] (R-HSA-387105) DYNLL1 [plasma membrane] (R-HSA-54017) DYNLL1 [ficolin-1-rich granule membrane] (R-HSA-6801518) DYNLL1 [tertiary granule membrane] (R-HSA-6801482) DYNLL1 [cilium] (R-HSA-5624863) DYNLL1 [ciliary tip] (R-HSA-5625335)	0.638	3
UniProt:Q14204 DYNC1H1	3	DYNC1H1 [cytosol] (R-HSA-380285) DYNC1H1 [azurophil granule lumen] (R-HSA-6799155) DYNC1H1 [extracellular region] (R-HSA-6806223)	0.638	3
UniProt:O43237 DYNC1LI2	1	DYNC1LI2 [cytosol] (R-HSA-2029025)	0.638	3
UniProt:Q96FJ2 DYNLL2	4	DYNLL2 [cytosol] (R-HSA-2029024) DYNLL2 [plasma membrane] (R-HSA-140527) DYNLL2 [cilium] (R-HSA-5624865) DYNLL2 [ciliary tip] (R-HSA-5625337)	0.638	3
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.556	3
UniProt:P12814 ACTN1	3	ACTN1 [platelet alpha granule lumen] (R-HSA-349724) ACTN1 [extracellular region] (R-HSA-349722) ACTN1 [cytosol] (R-HSA-354096)	0.556	3
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.556	3
UniProt:Q9BRX2 PELO	1	PELO [cytosol] (R-HSA-9954712)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:Q9H2F9 CCD68			0.556	3
UniProt:Q96HA8 NTAQ1			0.556	3
UniProt:O60884 DNAJA2	1	DNAJA2 [cytosol] (R-HSA-3371555)	0.556	3
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:Q99697-2 PITX2			0.556	3
UniProt:Q13409-3 DYNC1I2			0.556	3
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:Q99424 ACOX2	2	ACOX2 [cytosol] (R-HSA-9033151) ACOX2 [peroxisomal matrix] (R-HSA-192321)	0.556	3
IntAct:EBI-22325175 CCSB ORF ID			0.556	3
UniProt:Q9BTE6-2 AARSD1			0.556	3
UniProt:Q96PB7-3 OLFM3			0.556	3
UniProt:Q8N8B7-2 TCEANC			0.556	3
UniProt:Q4LE39-3 ARID4B			0.556	3
UniProt:Q5HYW2 NHSL2			0.556	3
UniProt:Q9H2R5 KLK15			0.556	3
UniProt:Q7L523 RRAGA	2	RRAGA [cytosol] (R-HSA-5653577) K63polyUb-K142,K220,K230,K244-RRAGA [cytosol] (R-HSA-8938830)	0.556	3
UniProt:Q9P0L2 MARK1			0.556	3
UniProt:P49190 PTH2R	1	PTH2R [plasma membrane] (R-HSA-420476)	0.556	3
UniProt:Q9UBY9 HSPB7			0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:A0A0H3MBG2 A0A0H3MBG2			0.543	5
UniProt:P07567 GAG			0.524	2
UniProt:Q8TF09 DYNLRB2	2	DYNLRB2 [ciliary tip] (R-HSA-5625341) DYNLRB2 [cilium] (R-HSA-5624869)	0.508	2
UniProt:Q9BQS6 HSPB9			0.508	5
UniProt:Q15555 MARE2			0.508	2
UniProt:P43034 PAFAH1B1	1	PAFAH1B1 [cytosol] (R-HSA-376249)	0.508	2
UniProt:P08670 VIM	12	Vimentin [lysosomal lumen] (R-HSA-9659977) Vimentin [cytosol] (R-HSA-9646687) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [late endosome lumen] (R-HSA-9660019) VIM [cytosol] (R-HSA-201600) VIM(2-259) [cytosol] (R-HSA-350323) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-429) [cytosol] (R-HSA-350317) VIM(430-466) [cytosol] (R-HSA-350316) VIM(86-466) [cytosol] (R-HSA-350294) VIM(2-85) [cytosol] (R-HSA-350264) p39-VIM [cytosol] (R-HSA-9948102)	0.508	2
UniProt:Q99873 PRMT1	2	PRMT1 [cytosol] (R-HSA-9632173) PRMT1 [nucleoplasm] (R-HSA-3215140)	0.508	2
UniProt:Q96EX3 DYNC2I2	2	WDR34 [ciliary tip] (R-HSA-5625407) WDR34 [cilium] (R-HSA-5624900)	0.508	2
UniProt:Q9NP97 DYNLRB1	2	DYNLRB1 [cilium] (R-HSA-5624868) DYNLRB1 [ciliary tip] (R-HSA-5625339)	0.508	2
UniProt:O75663 TIPRL			0.508	2
UniProt:Q8WVS4 DYNC2I1	2	WDR60 [ciliary tip] (R-HSA-5625409) WDR60 [cilium] (R-HSA-5624903)	0.508	2

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