Reactome | USP39 [nucleoplasm]

USP39 [nucleoplasm]

Stable Identifier

R-HSA-6806793

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U4/U6.U5 tri-snRNP-associated protein 2, SNUT2_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q15029 EFTUD2

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External Reference Information

External Reference

UniProt:Q53GS9 USP39

Gene Names

USP39, CGI-21, HSPC332, PRO2855

Chain

chain:1-565

Reference Genes

BioGPS Gene:10713 USP39

COSMIC (genes):USP39 USP39

CTD Gene:10713 USP39

dbSNP Gene:10713 USP39

ENSEMBL:ENSG00000168883 USP39

ENSEMBL_homo_sapiens_GENE:ENSG00000168883.20 USP39

HGNC:20071 USP39

KEGG Gene (Homo sapiens):10713 USP39

Monarch:10713 USP39

NCBI Gene:10713 USP39

OMIM:611594 USP39

UCSC:Q53GS9 USP39

Reference Transcript

Other Identifiers

10713

11716429_a_at

11744521_x_at

11747738_x_at

11749041_a_at

11754944_x_at

16882304

217829_PM_s_at

217829_s_at

2491708

2491709

2491710

2491711

2491713

2491714

2491715

2491716

2491717

2491718

2491719

2491720

2491721

2491722

2491723

2491727

2491728

2491733

2491734

2491735

2491736

2491737

2491738

48911_at

8043218

A_32_P101301

A_33_P3399840

GE61836

GO:0000245

GO:0000398

GO:0003824

GO:0004843

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0006397

GO:0006807

GO:0007049

GO:0008270

GO:0008380

GO:0016071

GO:0016579

GO:0016787

GO:0036211

GO:0043170

GO:0043226

GO:0044238

GO:0046540

GO:0046872

GO:0051301

GO:0065003

GO:0140096

HMNXSV003053359

ILMN_1659523

TC02000515.hg

g5730024_3p_a_at

Participates

as an output of

Formation of the Spliceosomal B complex (Homo sapiens)

as a component of

U4:U5:U6 tri-snRNP complex [nucleoplasm] (Homo sapiens)

Inferred To

Usp39 [nucleoplasm] (Drosophila melanogaster)

Usp39 [nucleoplasm] (Rattus norvegicus)

usp39 [nucleoplasm] (Dictyostelium discoideum)

usp39 [nucleoplasm] (Xenopus tropicalis)

USP39 [nucleoplasm] (Bos taurus)

USP39 [nucleoplasm] (Canis familiaris)

USP39 [nucleoplasm] (Mus musculus)

USP39 [nucleoplasm] (Plasmodium falciparum)

USP39 [nucleoplasm] (Schizosaccharomyces pombe)

USP39 [nucleoplasm] (Sus scrofa)

Ghost homologue of USP39 [nucleoplasm] (Gallus gallus)

usp-39 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001243655.1, XP_006711986.1, NP_001243657.1, XP_011530790.1, NP_001243656.1, NP_001243654.1, XP_016858671.1, XP_011530789.1, XP_006711985.1, NP_006581.2

OpenTargets

ENSG00000168883

GeneCards

Q53GS9

HPA

ENSG00000168883-USP39

Ensembl

ENST00000409766, ENST00000409470, ENSG00000168883, ENSP00000386803, ENST00000323701, ENST00000450066, ENSP00000312981, ENSP00000396133, ENSP00000386864

PRO

Q53GS9

Pharos - Targets

Q53GS9

PDB

8Y6O, 6QX9, 6AH0, 3JCR, 6QW6

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.744	4
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.643	3
UniProt:Q13523 PRPF4B	1	PRPF4B [nucleoplasm] (R-HSA-9769525)	0.643	3
UniProt:Q15029 EFTUD2	1	EFTUD2 [nucleoplasm] (R-HSA-71883)	0.615	3
UniProt:Q96SB4 SRPK1	2	SRPK1 [nucleoplasm] (R-HSA-9821984) SRPK1 [cytosol] (R-HSA-9729349)	0.59	2
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.59	3
UniProt:O43172 PRPF4	1	PRPF4 [nucleoplasm] (R-HSA-71890)	0.527	3
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.527	2
UniProt:O95218 ZRAB2			0.483	2

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