Deubiquitinated PTEN translocates to the cytosol

Stable Identifier
R-HSA-6807126
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm, cytosol
ReviewStatus
5/5
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Deubiquitinated PTEN translocates to the cytosol
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After nuclear monoubiquitinated PTEN gets deubiquitinated by USP7 (HAUSP), it translocates to the cytosol (Song et al. 2008).
Literature References
PubMed ID Title Journal Year
18716620 The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network

Pandolfi, PP, Carracedo, A, Egia, A, Song, MS, Teruya-Feldstein, J, Lo-Coco, F, Salmena, L

Nature 2008
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Authored
Orlic-Milacic, M  (2015-10-29)
Reviewed
Salmena, L  (2016-08-11)
Leslie, N  (2016-09-30)
Kriplani, N  (2016-09-30)
Carracedo, A  (2016-08-11)
Created
Orlic-Milacic, M  (2015-10-29)
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