Reactome | PGK2 [cytosol]

PGK2 [cytosol]

Stable Identifier

R-HSA-6807622

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Phosphoglycerate kinase 2

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
1278465	Characterization of phosphoglycerate kinase from human spermatozoa Donahue, RP, Scott, CR, Chen, SH	Fertil. Steril.	1976
3453121	Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene Thomas, K, McCarrey, JR	Nature	1987

External Reference Information

External Reference

UniProt:P07205 PGK2

Gene Names

PGK2, PGKB

Chain

initiator methionine:, chain:2-417

Reference Genes

BioGPS Gene:5232 PGK2

COSMIC (genes):PGK2 PGK2

CTD Gene:5232 PGK2

dbSNP Gene:5232 PGK2

ENSEMBL:ENSG00000170950 PGK2

HGNC:8898 PGK2

KEGG:hsa:5232 PGK2

Monarch:5232 PGK2

NCBI Gene:5232 PGK2

OMIM:172270 PGK2

UCSC:P07205 PGK2

Reference Transcript

RefSeq:NM_138733.4 PGK2

Other Identifiers

11737752_at

17019888

217009_PM_at

217009_at

2956587

2956588

2956589

2956590

3982481

4056085

5232

8126916

A_23_P331063

GO:0003824

GO:0004618

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0005829

GO:0005929

GO:0005975

GO:0006091

GO:0006094

GO:0006096

GO:0007018

GO:0016301

GO:0016310

GO:0016740

GO:0022414

GO:0030317

GO:0035686

GO:0043226

GO:0043531

GO:0048870

GO:0055086

GO:0061621

GO:0070062

GO:1901135

HMNXSV003048933

Hs.78771.2.S1_3p_at

ILMN_1692554

ILMN_2161955

PH_hs_0017515

TC06001786.hg

X05246_at

Participates

as a component of

PGK2 complex [cytosol] (Homo sapiens)

as a member of

PGK monomers [cytosol] (Homo sapiens)

Inferred To

Homologues of PGK2 [cytosol] (Drosophila melanogaster)

PGK2 [cytosol] (Caenorhabditis elegans)

PGK2 [cytosol] (Canis familiaris)

PGK2 [cytosol] (Danio rerio)

PGK2 [cytosol] (Dictyostelium discoideum)

PGK2 [cytosol] (Drosophila melanogaster)

PGK2 [cytosol] (Gallus gallus)

PGK2 [cytosol] (Mus musculus)

PGK2 [cytosol] (Plasmodium falciparum)

PGK2 [cytosol] (Rattus norvegicus)

PGK2 [cytosol] (Saccharomyces cerevisiae)

PGK2 [cytosol] (Schizosaccharomyces pombe)

PGK2 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_620061.2

ENSEMBL

ENST00000304801, ENSG00000170950, ENSP00000305995

OpenTargets

ENSG00000170950

GeneCards

PGK2

HPA

ENSG00000170950-PGK2

PRO

P07205

Pharos - Targets

P07205

GlyGen

P07205

HMDB Protein

HMDBP01502

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00558 PGK1	1	PGK1 [cytosol] (R-HSA-70483)	0.688	4
UniProt:Q9UHH9 IP6K2	1	IP6K2 [nucleoplasm] (R-HSA-1015687)	0.564	2
UniProt:P0DTC3 3a	9	O-glycosyl 3a [virion membrane] (R-COV-9694395) O-glycosyl 3a [endocytic vesicle membrane] (R-COV-9694729) O-glycosyl 3a [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694386) GalNAc-O-3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694658) 3a [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9694716) 3a [endoplasmic reticulum lumen] (R-COV-9694584) O-glycosyl 3a [endolysosome membrane] (R-COV-9754541) O-glycosyl 3a [plasma membrane] (R-COV-9694433) O-glycosyl 3a [extracellular region] (R-COV-9694387)	0.547	2
UniProt:P21579 SYT1	7	SYT1 [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-372508) SYT1 [plasma membrane] (R-HSA-168786) SYT1 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917741) SYT1 [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-372514) SYT1 [clathrin-sculpted acetylcholine transport vesicle membrane] (R-HSA-210536) SYT1 [synaptic vesicle membrane] (R-HSA-194789) SYT1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869113)	0.527	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-ESR1 [cytosol] (R-HSA-9632177) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.527	2

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