ALDH3B2 oxidises HXAL to PALM

Stable Identifier
R-HSA-6808464
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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ALDH3B2 (aldehyde dehydrogenase family 3 member B2), associated with cytosolic lipid droplets, catalyzes the NAD-dependent oxdidation of HXAL (hexadecanal) to PALM (palmitate). A geranylgeranylated cysteine residue mediates the enzyme's association with the lipid droplet (Kitamura et al. 2013, 2015).

Literature References
PubMed ID Title Journal Year
25286108 Mouse aldehyde dehydrogenase ALDH3B2 is localized to lipid droplets via two C-terminal tryptophan residues and lipid modification

Kitamura, T, Takagi, S, Naganuma, T, Kihara, A

Biochem. J. 2015
23721920 Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1

Kitamura, T, Naganuma, T, Abe, K, Nakahara, K, Ohno, Y, Kihara, A

Biochim. Biophys. Acta 2013
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
aldehyde dehydrogenase [NAD(P)+] activity of ALDH3B2 [lipid droplet]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created