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BET1 [transport vesicle]
Stable Identifier
R-HSA-6808719
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
transport vesicle
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
ERGIC-to-Golgi vesicles bind dynein:dynactin (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Homo sapiens)
RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Homo sapiens)
RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Homo sapiens)
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
BET1 [transport vesicle] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15155 BET1
Gene Names
BET1
Chain
chain:1-118
Reference Genes
BioGPS Gene:10282 BET1
COSMIC (genes):BET1 BET1
CTD Gene:10282 BET1
dbSNP Gene:10282 BET1
ENSEMBL:ENSG00000105829 BET1
HGNC:14562 BET1
KEGG:hsa:10282 BET1
Monarch:10282 BET1
NCBI Gene:10282 BET1
OMIM:605456 BET1
UCSC:O15155 BET1
Reference Transcript
RefSeq:NM_005868.5 BET1
RefSeq:NM_001317739.1 BET1
Other Identifiers
10282
11719815_at
11719816_s_at
11719817_x_at
11754136_x_at
202710_PM_at
202710_at
3061660
3061663
3061664
3061665
3061667
3061668
3061669
3061670
3061671
3061672
3061673
3061674
3061675
3061676
3061678
3061682
3061685
3061687
33434_at
33435_r_at
8141024
AF007551_at
A_23_P59700
A_24_P269432
GE54088
GO:0000139
GO:0005484
GO:0005515
GO:0005783
GO:0005789
GO:0005794
GO:0005801
GO:0006888
GO:0015031
GO:0016020
GO:0016192
GO:0030133
GO:0031201
GO:0031410
GO:0033116
GO:0043226
GO:0048280
GO:0060090
GO:0061024
HMNXSV003009690
HMNXSV003045033
ILMN_1684042
PH_hs_0002026
TC07001612.hg
g12654162_3p_at
p15009
Participates
as a member of
ERGIC-to-cis-Golgi cargo [transport vesicle] (Homo sapiens)
Other forms of this molecule
BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
BET1 [Golgi membrane]
Inferred To
Bet1 [transport vesicle]
(Drosophila melanogaster)
Bet1 [transport vesicle]
(Mus musculus)
Bet1 [transport vesicle]
(Rattus norvegicus)
bet1 [transport vesicle]
(Schizosaccharomyces pombe)
bet1 [transport vesicle]
(Xenopus tropicalis)
BET1 [transport vesicle]
(Bos taurus)
BET1 [transport vesicle]
(Canis familiaris)
BET1 [transport vesicle]
(Dictyostelium discoideum)
BET1 [transport vesicle]
(Gallus gallus)
BET1 [transport vesicle]
(Saccharomyces cerevisiae)
BET1 [transport vesicle]
(Sus scrofa)
nbet-1 [transport vesicle]
(Caenorhabditis elegans)
Cross References
OpenTargets
ENSG00000105829
ENSEMBL
ENST00000222547
,
ENSP00000391228
,
ENSP00000222547
,
ENST00000433727
HPA
ENSG00000105829-BET1
PRO
O15155
Pharos - Targets
O15155
GlyGen
O15155
PDB
3EGX
Interactors (67)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O14653 GOSR2
4
GOSR2 [endoplasmic reticulum membrane]
(R-HSA-5689451)
GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-535472)
GOSR2 [ER to Golgi transport vesicle membrane]
(R-HSA-5689800)
GOSR2 [Golgi membrane]
(R-HSA-6807755)
0.812
8
UniProt:P54920 NAPA
1
NAPA [cytosol]
(R-HSA-264469)
0.745
7
UniProt:Q12846 STX4
4
STX4 [plasma membrane]
(R-HSA-181519)
STX4 [phagocytic vesicle membrane]
(R-HSA-2029044)
STX4 [cytosol]
(R-HSA-114505)
p-STX4 [cytosol]
(R-HSA-114681)
0.718
6
UniProt:O75396 SEC22B
6
SEC22B [endoplasmic reticulum membrane]
(R-HSA-5688150)
SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688566)
SEC22B [ER to Golgi transport vesicle membrane]
(R-HSA-5688565)
SEC22B [phagocytic vesicle membrane]
(R-HSA-8863938)
SEC22B [transport vesicle]
(R-HSA-6810994)
SEC22B [Golgi membrane]
(R-HSA-6810993)
0.671
5
UniProt:Q8WVM8 SCFD1
1
SCFD1 [cytosol]
(R-HSA-5688147)
0.569
4
UniProt:Q99747 NAPG
1
NAPG [cytosol]
(R-HSA-5688555)
0.569
3
UniProt:O15400 STX7
0.569
3
UniProt:O95249 GOSR1
2
GOSR1 [transport vesicle]
(R-HSA-6784834)
GOSR1 [Golgi membrane]
(R-HSA-6807753)
0.569
3
UniProt:O15498 YKT6
5
PalmC-YKT6 [Golgi membrane]
(R-HSA-6808792)
PalmC-YKT6 [transport vesicle]
(R-HSA-6808794)
PalmC-YKT6 [endoplasmic reticulum membrane]
(R-HSA-5688145)
PalmC-YKT6 [ER to Golgi transport vesicle membrane]
(R-HSA-5688557)
PalmC-YKT6 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688558)
0.569
4
UniProt:Q13190 STX5
5
STX5 [cytosol]
(R-HSA-9613991)
STX5 [Golgi membrane]
(R-HSA-6807771)
STX5 [ER to Golgi transport vesicle membrane]
(R-HSA-5689838)
STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5688157)
STX5 [endoplasmic reticulum membrane]
(R-HSA-5689474)
0.569
4
UniProt:P46459 NSF
1
NSF [cytosol]
(R-HSA-264471)
0.569
3
UniProt:Q96AJ9 VTI1A
2
VTI1A [trans-Golgi network membrane]
(R-HSA-6813927)
VTI1A [Golgi membrane]
(R-HSA-6811035)
0.569
3
UniProt:Q99675 CGRF1
0.556
3
UniProt:P11912 CD79A
2
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
CD79A [plasma membrane]
(R-HSA-197154)
0.556
3
UniProt:Q96KR6 F210B
0.556
3
UniProt:Q9H115 NAPB
1
NAPB [cytosol]
(R-HSA-5688553)
0.556
3
UniProt:Q53FP2 NACHO
0.556
3
UniProt:Q8TBP5 F174A
0.556
3
UniProt:Q8TDT2 GP152
0.556
3
UniProt:P49447 CY561
0.556
3
UniProt:Q8WWH4 ASZ1
1
ASZ1 [cytosol]
(R-HSA-5603069)
0.556
3
UniProt:P07307-3 ASGR2
0.556
3
UniProt:Q9Y320 TMX2
0.556
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.556
3
UniProt:Q8IUN9 CLEC10A
1
CLEC10A [plasma membrane]
(R-HSA-1472863)
0.556
3
UniProt:P48051 KCNJ6
1
KCNJ6 [plasma membrane]
(R-HSA-975242)
0.556
3
UniProt:Q8N5K1 CISD2
0.556
3
UniProt:Q8N6Q1 TMC5A
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
UniProt:Q96Q45-2 TMEM237
0.556
3
UniProt:P04233-2 CD74
0.556
3
UniProt:O95471 CLDN7
2
CLDN7 [plasma membrane]
(R-HSA-420004)
CLDN7 [cell junction]
(R-HSA-421241)
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
UniProt:Q9Y282 ERGI3
0.556
3
UniProt:P61266 STX1B
3
STX1B(1-?) [cytosol]
(R-HSA-5246520)
STX1B(?-288) [plasma membrane]
(R-HSA-5246519)
STX1B [plasma membrane]
(R-HSA-181479)
0.556
3
UniProt:Q9BQA9 CYBC1
0.556
3
UniProt:Q8TBB6 S7A14
0.556
3
UniProt:Q6UWN5 LYPD5
2
cleaved GPI-LYPD5 [extracellular region]
(R-HSA-8941140)
GPI-LYPD5 [plasma membrane]
(R-HSA-8940779)
0.556
3
UniProt:Q8N6L0 KASH5
0.556
3
UniProt:P32856-2 STX2
0.556
3
UniProt:Q8WWF3 SSMM1
0.556
3
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.556
3
UniProt:P43360 MAGA6
0.556
3
UniProt:Q9GZY8-5 MFF
0.556
3
UniProt:Q9BXS9-3 SLC26A6
0.556
3
UniProt:Q68DC2 ANKS6
0.556
3
UniProt:Q96HE8 TMM80
0.556
3
UniProt:Q86VR2 RETR3
0.556
3
UniProt:Q8N5M9 JAGN1
0.556
3
UniProt:Q9GZR5 ELOVL4
1
ELOVL4 [endoplasmic reticulum membrane]
(R-HSA-548705)
0.556
3
UniProt:O14684 PTGES
1
PTGES [endoplasmic reticulum membrane]
(R-HSA-2142717)
0.556
3
UniProt:Q5JX71 F209A
0.556
3
UniProt:Q9H6H4 REEP4
0.556
3
UniProt:O14880 MGST3
1
MGST3 [endoplasmic reticulum membrane]
(R-HSA-176053)
0.556
3
UniProt:P29274 ADORA2A
2
ADORA2A [plasma membrane]
(R-HSA-418934)
ADORA2A [Golgi membrane]
(R-HSA-187668)
0.556
3
UniProt:Q9BUF7-2 CRB3
0.556
3
UniProt:Q4KMG9 TM52B
0.556
3
UniProt:Q13061 TRDN
1
TRDN [sarcoplasmic reticulum lumen]
(R-HSA-2855215)
0.527
2
UniProt:Q9BV40 VAMP8
11
VAMP8 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869137)
VAMP8 [secretory granule membrane]
(R-HSA-376368)
VAMP8 [cytoplasmic vesicle membrane]
(R-HSA-376373)
VAMP8 [Golgi membrane]
(R-HSA-266201)
VAMP8 [lysosomal membrane]
(R-HSA-432710)
VAMP8 [phagocytic vesicle membrane]
(R-HSA-8863896)
VAMP8 [recycling endosome membrane]
(R-HSA-8863891)
VAMP8 [tertiary granule membrane]
(R-HSA-6801024)
VAMP8 [specific granule membrane]
(R-HSA-6799707)
VAMP8 [plasma membrane]
(R-HSA-376365)
VAMP8 [azurophil granule membrane]
(R-HSA-6799703)
0.527
2
UniProt:Q96CS2 HAUS1
1
HAUS1 [cytosol]
(R-HSA-8855199)
0.527
2
UniProt:Q9UHF4 IL20RA
1
IL20RA [plasma membrane]
(R-HSA-448713)
0.527
2
UniProt:Q9P2W9 STX18
1
STX18 [endoplasmic reticulum membrane]
(R-HSA-2029079)
0.527
3
UniProt:Q8N6Y0 USBP1
0.508
2
UniProt:P51809 VAMP7
6
VAMP7 [late endosome membrane]
(R-HSA-2193120)
VAMP7 [lysosomal membrane]
(R-HSA-376342)
VAMP7 [plasma membrane]
(R-HSA-376361)
VAMP7 [Golgi membrane]
(R-HSA-266197)
VAMP7 [cytoplasmic vesicle membrane]
(R-HSA-376336)
VAMP7 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869135)
0.483
2
UniProt:Q9H8Y8 GORASP2
2
p-T222,T225-GORASP2 [Golgi membrane]
(R-HSA-2422965)
GORASP2 [Golgi membrane]
(R-HSA-2422385)
0.483
2
UniProt:Q13948 CUX1
1
CUX1 [Golgi membrane]
(R-HSA-8847510)
0.483
2
UniProt:O43752 STX6
2
STX6 [trans-Golgi network membrane]
(R-HSA-6811007)
STX6 [Golgi membrane]
(R-HSA-6811004)
0.483
2
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