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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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ReactomeFIViz
Developer's Zone
Graph Database
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Content Service
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Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
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Curator Guide
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FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
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KRT40 [cytosol]
Stable Identifier
R-HSA-6809605
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Keratin, type I cytoskeletal 40, K1C40_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of hair keratin fibres (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome network [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
CDSN binds the cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Filaggrin binds Keratin tonofilament:Desmosome (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Fillagrin and keratin intermediate filaments polymerize forming a network (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Lamellar bodies bind the early cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
No FGN-cornified envelope:CDSN [cornified envelope] (Homo sapiens)
No FGN-Cornified envelope [cornified envelope] (Homo sapiens)
No FGN-early cornified envelope [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome network [cornified envelope] (Homo sapiens)
Keratin tonofilament:Desmosome [cornified envelope] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome network [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Reinforcement of the Cornified Envelope (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
FLG-Keratin filament network [plasma membrane] (Homo sapiens)
FLG(?-?):Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Formation of tonofilament bundles (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filament formation (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin filaments bind cell-cell adhesion complexes (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tonofilament:Desmosome [plasma membrane] (Homo sapiens)
Keratin tonofilament [cytosol] (Homo sapiens)
Keratin filament [cytosol] (Homo sapiens)
Keratin filament units [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tetramers bind to form unit length filaments (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin unit length filament [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I binds keratin type II (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin type I/type II heterodimers form tetramers (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
Keratin tetramer [cytosol] (Homo sapiens)
Keratin heterodimer [cytosol] (Homo sapiens)
Keratin type I [cytosol] (Homo sapiens)
Keratin type I, hair specific [cytosol] (Homo sapiens)
KRT40 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6A162 KRT40
Gene Names
KRT40, KA36
Chain
chain:1-431
Reference Genes
BioGPS Gene:125115 KRT40
COSMIC (genes):KRT40 KRT40
CTD Gene:125115 KRT40
dbSNP Gene:125115 KRT40
ENSEMBL:ENSG00000204889 KRT40
HGNC:26707 KRT40
KEGG:hsa:125115 KRT40
Monarch:125115 KRT40
NCBI Gene:125115 KRT40
OMIM:616679 KRT40
UCSC:Q6A162 KRT40
Reference Transcript
RefSeq:NM_001389244.1 KRT40
RefSeq:NM_182497.4 KRT40
RefSeq:NM_001385217.1 KRT40
Other Identifiers
11738403_at
11738404_s_at
125115
1562628_PM_at
1562628_at
1562629_PM_a_at
1562629_a_at
16844533
3756631
3756633
3756634
3756636
3756637
3756638
3756639
3756641
3756643
3756644
3756645
3756646
3756647
3756648
8015152
8019604
A_33_P3310894
GE477047
GO:0002009
GO:0005198
GO:0005515
GO:0005829
GO:0005856
GO:0005882
GO:0007010
GO:0030154
GO:0030280
GO:0030855
GO:0045095
GO:0045109
HMNXSV003005746
Hs2.146635.1.S1_3p_at
ILMN_1658563
ILMN_1663578
ILMN_2201768
PH_hs_0031822
PH_hs_0040615
TC17001475.hg
Participates
as a member of
Keratin type I, hair specific [cytosol] (Homo sapiens)
Inferred To
Homologues of KRT40 [cytosol]
(Danio rerio)
krt92 [cytosol]
(Danio rerio)
krt91 [cytosol]
(Danio rerio)
cyt1l [cytosol]
(Danio rerio)
cyt1 [cytosol]
(Danio rerio)
krt17 [cytosol]
(Danio rerio)
Krt40 [cytosol]
(Mus musculus)
Krt40 [cytosol]
(Rattus norvegicus)
krt70 [cytosol]
(Xenopus tropicalis)
krt97 [cytosol]
(Danio rerio)
krt15 [cytosol]
(Danio rerio)
KRT40 [cytosol]
(Bos taurus)
KRT40 [cytosol]
(Canis familiaris)
KRT40 [cytosol]
(Sus scrofa)
krt1-19e [cytosol]
(Danio rerio)
krt99 [cytosol]
(Danio rerio)
krt1-19d [cytosol]
(Danio rerio)
krt98 [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_872303.2
,
NP_001376173.1
,
NP_001372146.1
OpenTargets
ENSG00000204889
ENSEMBL
ENSP00000366984
,
ENST00000576967
,
ENSP00000381500
,
ENSP00000459621
,
ENST00000377755
,
ENST00000610983
,
ENSG00000262845
,
ENST00000398486
,
ENSP00000506768
,
ENST00000684280
,
ENSG00000204889
,
ENSP00000479080
GeneCards
KRT40
HPA
ENSG00000204889-KRT40
PRO
Q6A162
Pharos - Targets
Q6A162
GlyGen
Q6A162
Interactors (64)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P40222 TXLNA
1
TXLNA [cytosol]
(R-HSA-449124)
0.782
8
UniProt:P62195 PSMC5
2
PSMC5 [cytosol]
(R-HSA-68780)
PSMC5 [nucleoplasm]
(R-HSA-174312)
0.742
5
UniProt:P99999 CYCS
6
CYCS [cytosol]
(R-HSA-53259)
CYCS [mitochondrial intermembrane space]
(R-HSA-114244)
Cytochrome c (reduced) [mitochondrial inner membrane]
(R-HSA-352609)
Cytochrome c (oxidised) [mitochondrial inner membrane]
(R-HSA-352607)
apo-CYCS [mitochondrial inner membrane]
(R-HSA-352608)
AcK-CYCS [mitochondrial intermembrane space]
(R-HSA-5688308)
0.718
6
UniProt:Q92608 DOCK2
3
DOCK2 [specific granule lumen]
(R-HSA-6799558)
DOCK2 [extracellular region]
(R-HSA-6806310)
DOCK2 [cytosol]
(R-HSA-200938)
0.718
6
UniProt:O95363 FARS2
1
FARS2(1-?) [mitochondrial matrix]
(R-HSA-379565)
0.718
6
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.718
6
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.718
8
UniProt:Q15561 TEAD4
1
TEAD4 [nucleoplasm]
(R-HSA-2032780)
0.718
6
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.718
6
UniProt:Q96BZ8 LENG1
1
LENG1 [nucleoplasm]
(R-HSA-9769590)
0.718
6
UniProt:Q969G3 SMARCE1
1
SMARCE1 [nucleoplasm]
(R-HSA-389258)
0.718
6
UniProt:O95863 SNAI1
1
SNAI1 [nucleoplasm]
(R-HSA-2980903)
0.666
4
UniProt:Q13330 MTA1
2
MTA1 [nucleoplasm]
(R-HSA-3465550)
polySUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
0.666
4
UniProt:P19544 WT1
1
WT1 [nucleoplasm]
(R-HSA-452420)
0.666
4
UniProt:Q9H1K1 ISCU
1
ISCU [cytosol]
(R-HSA-9771680)
0.556
3
UniProt:Q9UIL1 SCOC
1
SCOC [cytosol]
(R-HSA-6813911)
0.556
3
UniProt:P29597 TYK2
5
p-Y1054-TYK2 [cytosol]
(R-HSA-1112598)
p-Y1054,Y1055-TYK2 [cytosol]
(R-HSA-909682)
TYK2 [cytosol]
(R-HSA-877348)
p-TYK2 [cytosol]
(R-HSA-8950424)
p-Y-TYK2 [cytosol]
(R-HSA-6784366)
0.556
3
UniProt:P25786 PSMA1
2
PSMA1 [cytosol]
(R-HSA-68724)
PSMA1 [nucleoplasm]
(R-HSA-174333)
0.556
3
UniProt:Q49AN0 CRY2
5
CRY2 [cytosol]
(R-HSA-400255)
p-S-CRY2 [nucleoplasm]
(R-HSA-400328)
p-S-CRY2 [cytosol]
(R-HSA-400305)
K48polyUb-K126,p-S-CRY2 [cytosol]
(R-HSA-9932882)
K48polyUb-K,p-S-CRY2 [nucleoplasm]
(R-HSA-517935)
0.556
3
UniProt:P48023 FASLG
1
FASLG(1-281) [extracellular region]
(R-HSA-66212)
0.556
3
UniProt:Q13875 MOBP
1
MOBP [cytosol]
(R-HSA-9022884)
0.556
3
UniProt:P43353 ALDH3B1
3
ALDH3B1 [plasma membrane]
(R-HSA-5696096)
ALDH3B1 [secretory granule membrane]
(R-HSA-6801023)
ALDH3B1 [specific granule membrane]
(R-HSA-6799510)
0.556
3
UniProt:O15169 AXIN1
11
AXIN1 [cytosol]
(R-HSA-195249)
p-T481,S486,S493-AXIN1 [cytosol]
(R-HSA-206040)
Ub-RibC-AXIN1 [cytosol]
(R-HSA-3640864)
RibC-AXIN1 [cytosol]
(R-HSA-3640841)
ub-AXIN1 [cytosol]
(R-HSA-4641133)
AXIN1 P255S [cytosol]
(R-HSA-5251505)
AXIN1 P354L [cytosol]
(R-HSA-5251511)
AXIN1 W247* [cytosol]
(R-HSA-5251512)
AXIN1 E406* [cytosol]
(R-HSA-5251500)
AXIN1 Y346* [cytosol]
(R-HSA-4839753)
AXIN1 L396M [cytosol]
(R-HSA-5251503)
0.556
3
UniProt:P20138 CD33
3
CD33 [specific granule membrane]
(R-HSA-6799615)
CD33 [plasma membrane]
(R-HSA-197719)
CD33 [tertiary granule membrane]
(R-HSA-6800959)
0.556
3
UniProt:P20618 PSMB1
7
PSMB1 [cytosol]
(R-HSA-68738)
PSMB1 [nucleoplasm]
(R-HSA-174347)
pro-PSMB1 [cytosol]
(R-HSA-9908139)
PSMB1(1-28) [cytosol]
(R-HSA-9908143)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
0.556
3
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.556
3
UniProt:Q9NX63 CHCHD3
3
CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874907)
4xHC-CHCHD3 [mitochondrial intermembrane space]
(R-HSA-8874910)
CHCHD3 (MIC19) [mitochondrial inner membrane]
(R-HSA-8949583)
0.556
3
UniProt:Q92993 KAT5
1
KAT5 [nucleoplasm]
(R-HSA-3321979)
0.556
3
UniProt:P63000 RAC1
6
RAC1 [plasma membrane]
(R-HSA-351141)
RAC1 [cytosol]
(R-HSA-442615)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:Q9UBX3 SLC25A10
1
SLC25A10 [mitochondrial inner membrane]
(R-HSA-372848)
0.556
3
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.556
3
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
0.556
3
UniProt:O43602 DCX
1
DCX [cytosol]
(R-HSA-430060)
0.556
3
UniProt:Q9H257 CARD9
3
CARD9 [cytosol]
(R-HSA-561194)
CARD9 [plasma membrane]
(R-HSA-5607662)
p-T231-CARD9 [plasma membrane]
(R-HSA-5607623)
0.556
3
UniProt:P26441 CNTF
1
CNTF [extracellular region]
(R-HSA-5696441)
0.556
3
UniProt:P56524 HDAC4
3
HDAC4 [nucleoplasm]
(R-HSA-351581)
monoSUMO1-K559-HDAC4 [nucleoplasm]
(R-HSA-4616016)
polySUMO2,3-K559-HDAC4 [nucleoplasm]
(R-HSA-4616029)
0.556
3
UniProt:Q13526 PIN1
2
PIN1 [nucleoplasm]
(R-HSA-936016)
PIN1 [cytosol]
(R-HSA-9626823)
0.556
3
UniProt:Q92835 INPP5D
2
INPP5D [cytosol]
(R-HSA-197940)
p-Y-INPP5D [cytosol]
(R-HSA-9680730)
0.556
3
UniProt:Q9H2F3 HSD3B7
1
HSD3B7 [endoplasmic reticulum membrane]
(R-HSA-193441)
0.556
3
UniProt:P08631 HCK
2
HCK [cytosol]
(R-HSA-167708)
p-HCK [cytosol]
(R-HSA-9676060)
0.556
3
UniProt:Q99633 PRPF18
1
PRPF18 [nucleoplasm]
(R-HSA-5688093)
0.556
3
UniProt:O95391 SLU7
1
hSLU7 [nucleoplasm]
(R-HSA-72073)
0.556
3
UniProt:P31273 HOXC8
1
HOXC8 [nucleoplasm]
(R-HSA-3222311)
0.556
3
UniProt:Q99757 TXN2
2
TXN2 [mitochondrial matrix]
(R-HSA-3323048)
2xHC-TXN2 [mitochondrial matrix]
(R-HSA-3323059)
0.556
3
UniProt:Q99728 BARD1
13
K6PolyUb,p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-9707286)
p-T714,T734-BARD1 [nucleoplasm]
(R-HSA-5659846)
BARD1 [nucleoplasm]
(R-HSA-5659775)
K6PolyUb-BARD1 [nucleoplasm]
(R-HSA-9701024)
BARD1 C83G [nucleoplasm]
(R-HSA-9699139)
BARD1 C50G [nucleoplasm]
(R-HSA-9699137)
BARD1 L44R [nucleoplasm]
(R-HSA-9699126)
BARD1 H68Y [nucleoplasm]
(R-HSA-9699151)
BARD1 W34R [nucleoplasm]
(R-HSA-9699166)
BARD1 G623W [nucleoplasm]
(R-HSA-9699148)
BARD1 C53W [nucleoplasm]
(R-HSA-9700807)
BARD1 C71Y [nucleoplasm]
(R-HSA-9700808)
BARD1 G623E [nucleoplasm]
(R-HSA-9699135)
0.556
3
UniProt:P55040 GEM
1
GEM [plasma membrane]
(R-HSA-9769962)
0.556
3
UniProt:O60573 EIF4E2
1
EIF4E2 [cytosol]
(R-HSA-1678822)
0.556
3
UniProt:P55081 MFAP1
1
MFAP1 [nucleoplasm]
(R-HSA-2396419)
0.556
3
UniProt:Q96HC4 PDLIM5
1
PDLIM5 [cytosol]
(R-HSA-6794246)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:P52292 KPNA2
2
KPNA2 [cytosol]
(R-HSA-205976)
KPNA2 [nucleoplasm]
(R-HSA-206045)
0.556
3
UniProt:Q4G176 ACSF3
1
ACSF3 [mitochondrial matrix]
(R-HSA-5696011)
0.556
3
UniProt:Q96E11 MRRF
1
MRRF [mitochondrial matrix]
(R-HSA-5419265)
0.556
3
UniProt:P23769 GATA2
1
GATA2 [nucleoplasm]
(R-HSA-996735)
0.556
3
UniProt:Q9BZF9 UACA
1
UACA [cytosol]
(R-HSA-6804636)
0.556
3
UniProt:Q9UBR2 CTSZ
9
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum lumen]
(R-HSA-5689431)
(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle]
(R-HSA-5689727)
(Glc)3(GlcNAc)2(Man)9-CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-5689730)
CTSZ [plasma membrane]
(R-HSA-2022345)
CTSZ [specific granule lumen]
(R-HSA-6801304)
CTSZ [extracellular region]
(R-HSA-6801569)
CTSZ [ficolin-1-rich granule lumen]
(R-HSA-6801318)
CTSZ [lysosomal lumen]
(R-HSA-429814)
CTSZ [Golgi lumen]
(R-HSA-434321)
0.556
3
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.556
3
UniProt:Q9UBU9 NXF1
2
NXF1 [nucleoplasm]
(R-HSA-111690)
NXF1 [cytosol]
(R-HSA-156481)
0.556
3
UniProt:Q2TBE0 CWF19L2
1
CWF19L2 [nucleoplasm]
(R-HSA-9770846)
0.556
3
UniProt:P51959 CCNG1
1
CCNG1 [nucleoplasm]
(R-HSA-6792489)
0.556
3
UniProt:Q9UBK9 UXT
1
UXT [nucleoplasm]
(R-HSA-9007484)
0.556
3
UniProt:Q96NC0 ZMAT2
1
ZMAT2 [nucleoplasm]
(R-HSA-9770248)
0.556
3
UniProt:Q8WUK0 PTPMT1
1
PTPMT1 [mitochondrial inner membrane]
(R-HSA-3446802)
0.556
3
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