Reactome | KRTAP10-5 [cytosol]

KRTAP10-5 [cytosol]

Stable Identifier

R-HSA-6810260

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 10-5, KR105_HUMAN

Locations in the PathwayBrowser

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Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP10s [cytosol] (Homo sapiens)
        
        KRTAP10-5 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP10s [cytosol] (Homo sapiens)
        
        KRTAP10-5 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P60370 KRTAP10-5

Gene Names

KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5

Chain

chain:1-271

Reference Genes

COSMIC (genes):KRTAP10-5 KRTAP10-5

ENSEMBL:ENSG00000241123 KRTAP10-5

HGNC:22969 KRTAP10-5

UCSC:P60370 KRTAP10-5

Other Identifiers

11734635_at

11734636_x_at

16926393

386680

3934592

3934593

3934594

3934595

8070782

CCDS42958

ENSG00000241123

ENSP00000383223

ENST00000400372

ENST00000400372.1

EntrezGene:386680

EntrezGene:KRTAP10-5

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005829

GO:0005856

GO:0005882

GO:0008150

GO:0030154

GO:0031424

GO:0042802

GO:0043226

GO:0045095

GO:0048856

HGNC:22969

ILMN_1657191

IPR002494

KRTAP10-5

KRTAP10-5-201

NM_198694

NP_941967

PF13885

TC21000530.hg

TC21001035.hg

UPI00003D4D6F

Participant Of

hasMember

KRTAP10s [cytosol]

Inferred To

Homologues of KRTAP10-5 [cytosol] (Rattus norvegicus)

KRTAP10-5 [cytosol] (Bos taurus)

KRTAP10-5 [cytosol] (Canis familiaris)

KRTAP10-5 [cytosol] (Mus musculus)

KRTAP10-5 [cytosol] (Rattus norvegicus)

KRTAP10-5 [cytosol] (Sus scrofa)

Cross References

OpenTargets

ENSG00000241123

GeneCards

P60370

PRO

P60370

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.696	5
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.696	5
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) p-T231-CARD9 [plasma membrane] (R-HSA-5607623) CARD9 [plasma membrane] (R-HSA-5607662)	0.556	3
UniProt:O95363 FARS2	1	FARS2(1-?) [mitochondrial matrix] (R-HSA-379565)	0.556	3
UniProt:O60573 EIF4E2	1	EIF4E2 [cytosol] (R-HSA-1678822)	0.556	3
UniProt:Q13875 MOBP	1	MOBP [cytosol] (R-HSA-9022884)	0.556	3
UniProt:P43353 ALDH3B1	3	ALDH3B1 [plasma membrane] (R-HSA-5696096) ALDH3B1 [secretory granule membrane] (R-HSA-6801023) ALDH3B1 [specific granule membrane] (R-HSA-6799510)	0.556	3
UniProt:Q92692 NECTIN2	1	PVRL2 [plasma membrane] (R-HSA-419006)	0.556	3
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.556	3
UniProt:O43597 SPRY2	8	p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) SPRY2 [plasma membrane] (R-HSA-182924) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) SPRY2 [cytosol] (R-HSA-182949) p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55-SPRY2 [cytosol] (R-HSA-182950)	0.556	3
UniProt:Q9NP91 SLC6A20	2	SLC6A20 [plasma membrane] (R-HSA-352058) SLC6A20 T199M [plasma membrane] (R-HSA-5660705)	0.556	3
UniProt:P42892 ECE1	1	ECE1 [plasma membrane] (R-HSA-8876866)	0.556	3
UniProt:P22736 NR4A1	2	NR4A1 [nucleoplasm] (R-HSA-199831) p-S351-NR4A1 [nucleoplasm] (R-HSA-199846)	0.556	3
UniProt:Q13895 BYSL	2	BYSL [cytosol] (R-HSA-6791518) BYSL [nucleoplasm] (R-HSA-6791526)	0.556	5
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.488	2
UniProt:Q92570 NR4A3	1	NR4A3 [nucleoplasm] (R-HSA-8938004)	0.488	2
UniProt:P10745 RBP3	1	RBP3 [extracellular region] (R-HSA-2984190)	0.488	2
UniProt:Q12837 POU4F2	1	POU4F2 [nucleoplasm] (R-HSA-6804414)	0.488	2