Reactome | KRTAP6-2 [cytosol]

KRTAP6-2 [cytosol]

Stable Identifier

R-HSA-6810261

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 6-2, KRA62_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP6s [cytosol] (Homo sapiens)
        
        KRTAP6-2 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP6s [cytosol] (Homo sapiens)
        
        KRTAP6-2 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q3LI66 KRTAP6-2

Gene Names

KRTAP6-2, KAP6.2

Chain

chain:1-62

Reference Genes

BioGPS Gene:337967 KRTAP6-2

COSMIC (genes):KRTAP6-2 KRTAP6-2

CTD Gene:337967 KRTAP6-2

dbSNP Gene:337967 KRTAP6-2

ENSEMBL:ENSG00000186930 KRTAP6-2

HGNC:18932 KRTAP6-2

KEGG Gene (Homo sapiens):337967 KRTAP6-2

Monarch:337967 KRTAP6-2

NCBI Gene:337967 KRTAP6-2

UCSC:Q3LI66 KRTAP6-2

Reference Transcript

RefSeq:NM_181604.1 KRTAP6-2

Other Identifiers

0006450193

11715130_s_at

11759380_at

16924852

337967

3928552

3928553

3928554

8069848

A_33_P3263664

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005829

GO:0005856

GO:0005882

GO:0008150

GO:0030154

GO:0031424

GO:0042802

GO:0043226

GO:0048856

HMNXSV003019029

ILMN_1722755

TC21000380.hg

Participates

as a member of

KRTAP6s [cytosol] (Homo sapiens)

Inferred To

Gm10229 [cytosol] (Mus musculus)

Krtap6-5 [cytosol] (Mus musculus)

LOC618359 [cytosol] (Bos taurus)

KRTAP6-2 [cytosol] (Rattus norvegicus)

LOC112446984 [cytosol] (Bos taurus)

1110025L11Rik [cytosol] (Mus musculus)

Homologues of KRTAP6-2 [cytosol] (Bos taurus)

Homologues of KRTAP6-2 [cytosol] (Mus musculus)

Homologues of KRTAP6-2 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_853635.1

OpenTargets

ENSG00000186930

HPA

ENSG00000186930-KRTAP6-2

GeneCards

Q3LI66

Ensembl

ENST00000334897, ENSG00000186930, ENSP00000334560

PRO

Q3LI66

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12891 HYAL2	1	HYAL2 [plasma membrane] (R-HSA-2160919)	0.556	3
UniProt:Q99895 CTRC	1	CTRC [extracellular region] (R-HSA-5693362)	0.556	3
UniProt:Q8IVS8 GLYCTK	1	GLYCTK [cytosol] (R-HSA-6799244)	0.556	5
UniProt:Q9NQ87 HEYL	1	HEYL [nucleoplasm] (R-HSA-1606748)	0.556	3
UniProt:O15234 CASC3	2	CASC3 [cytosol] (R-HSA-927807) CASC3 [nucleoplasm] (R-HSA-8849148)	0.556	5
UniProt:Q01974 ROR2	2	ROR2 [clathrin-coated endocytic vesicle membrane] (R-HSA-5140729) ROR2 [plasma membrane] (R-HSA-197731)	0.556	3
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [azurophil granule lumen] (R-HSA-6799709) TOLLIP [cytosol] (R-HSA-446885) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [specific granule lumen] (R-HSA-6799719)	0.556	5
UniProt:Q8TCT0 CERK	1	CERK [plasma membrane] (R-HSA-1631584)	0.556	3
UniProt:Q9UBP5 HEY2	1	HEY2 [nucleoplasm] (R-HSA-1606745)	0.556	3
UniProt:O95231 VENTX	1	VENTX [nucleoplasm] (R-HSA-8853887)	0.556	5
UniProt:Q9Y5J3 HEY1	1	HEY1 [nucleoplasm] (R-HSA-1606744)	0.556	3
UniProt:O43559 FRS3	3	FRS3 [plasma membrane] (R-HSA-191482) p-5Y-FRS3 [plasma membrane] (R-HSA-191475) p-Y-FRS3 [plasma membrane] (R-HSA-9032427)	0.556	5
UniProt:P07902 GALT	4	GALT K285N [cytosol] (R-HSA-5610009) GALT Q188R [cytosol] (R-HSA-5610008) GALT S135L [cytosol] (R-HSA-5610004) GALT [cytosol] (R-HSA-70356)	0.556	3
UniProt:Q6PJG9 LRFN4	1	SALM3 [plasma membrane] (R-HSA-197883)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q13227 GPS2	1	GPS2 [nucleoplasm] (R-HSA-351642)	0.556	5
UniProt:Q9BZS1 FOXP3	1	FOXP3 [nucleoplasm] (R-HSA-8865539)	0.556	3
UniProt:O14503 BHLHE40	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.556	3

Cite Us!