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KRTAP10-8 [cytosol]
Stable Identifier
R-HSA-6810301
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Keratin-associated protein 10-8, KR108_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of hair keratin fibres (Homo sapiens)
Keratin associated proteins [cytosol] (Homo sapiens)
KRTAP10s [cytosol] (Homo sapiens)
KRTAP10-8 [cytosol] (Homo sapiens)
Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
Keratin associated proteins [cytosol] (Homo sapiens)
KRTAP10s [cytosol] (Homo sapiens)
KRTAP10-8 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P60410 KRTAP10-8
Gene Names
KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Chain
chain:1-259
Reference Genes
BioGPS Gene:386681 KRTAP10-8
COSMIC (genes):KRTAP10-8 KRTAP10-8
CTD Gene:386681 KRTAP10-8
dbSNP Gene:386681 KRTAP10-8
ENSEMBL:ENSG00000187766 KRTAP10-8
HGNC:20525 KRTAP10-8
KEGG Gene (Homo sapiens):386681 KRTAP10-8
Monarch:386681 KRTAP10-8
NCBI Gene:386681 KRTAP10-8
UCSC:P60410 KRTAP10-8
Reference Transcript
RefSeq:NM_198695.2 KRTAP10-8
Other Identifiers
11715321_x_at
16923656
386681
3923855
3923856
3923861
3923877
3934575
3934579
3934580
8069148
A_33_P3293760
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005856
GO:0005882
GO:0008150
GO:0030154
GO:0031424
GO:0042802
GO:0043226
GO:0045095
GO:0048856
ILMN_1793716
PH_hs_0034603
TC21000232.hg
Participant Of
hasMember
KRTAP10s [cytosol]
Inferred To
RGD1561557 [cytosol] (Rattus norvegicus)
Gm3250 [cytosol] (Mus musculus)
Gm9508 [cytosol] (Mus musculus)
Krtap10-4 [cytosol] (Mus musculus)
Homologues of KRTAP10-8 [cytosol] (Bos taurus)
Homologues of KRTAP10-8 [cytosol] (Canis familiaris)
Homologues of KRTAP10-8 [cytosol] (Mus musculus)
Homologues of KRTAP10-8 [cytosol] (Rattus norvegicus)
Homologues of KRTAP10-8 [cytosol] (Sus scrofa)
Gm7138 [cytosol] (Mus musculus)
KRTAP10-8 [cytosol] (Bos taurus)
KRTAP10-8 [cytosol] (Canis familiaris)
KRTAP10-8 [cytosol] (Rattus norvegicus)
KRTAP10-8 [cytosol] (Sus scrofa)
Gm3285 [cytosol] (Mus musculus)
Gm10318 [cytosol] (Mus musculus)
LOC102160031 [cytosol] (Sus scrofa)
LOC100622826 [cytosol] (Sus scrofa)
LOC686720 [cytosol] (Rattus norvegicus)
Gm19402 [cytosol] (Mus musculus)
Gm9639 [cytosol] (Mus musculus)
Gm9507 [cytosol] (Mus musculus)
Gm19668 [cytosol] (Mus musculus)
LOC687631 [cytosol] (Rattus norvegicus)
Gm18596 [cytosol] (Mus musculus)
Gm7137 [cytosol] (Mus musculus)
LOC690460 [cytosol] (Rattus norvegicus)
Gm9736 [cytosol] (Mus musculus)
LOC103694398 [cytosol] (Rattus norvegicus)
Krtap10-10 [cytosol] (Mus musculus)
Gm3233 [cytosol] (Mus musculus)
Gm3238 [cytosol] (Mus musculus)
LOC690478 [cytosol] (Rattus norvegicus)
Cross References
RefSeq
NP_941968.2
OpenTargets
ENSG00000187766
HPA
ENSG00000187766-KRTAP10-8
GeneCards
P60410
Ensembl
ENST00000334662
,
ENSP00000335565
,
ENSG00000187766
PRO
P60410
Interactors (58)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8WUK0 PTPMT1
1
PTPMT1 [mitochondrial inner membrane]
(R-HSA-3446802)
0.718
6
UniProt:P15151 PVR
1
PVR [plasma membrane]
(R-HSA-420600)
0.718
6
UniProt:Q9UBK9 UXT
1
UXT [nucleoplasm]
(R-HSA-9007484)
0.718
6
UniProt:Q92608 DOCK2
3
DOCK2 [extracellular region]
(R-HSA-6806310)
DOCK2 [specific granule lumen]
(R-HSA-6799558)
DOCK2 [cytosol]
(R-HSA-200938)
0.718
6
UniProt:Q8IW45 NAXD
1
CARKD [mitochondrial matrix]
(R-HSA-6806970)
0.718
6
UniProt:O76003 GLRX3
1
GLRX3 [cytosol]
(R-HSA-5691202)
0.718
8
UniProt:P43353 ALDH3B1
3
ALDH3B1 [plasma membrane]
(R-HSA-5696096)
ALDH3B1 [specific granule membrane]
(R-HSA-6799510)
ALDH3B1 [secretory granule membrane]
(R-HSA-6801023)
0.718
6
UniProt:Q9H2F3 HSD3B7
1
HSD3B7 [endoplasmic reticulum membrane]
(R-HSA-193441)
0.718
8
UniProt:Q9NP91 SLC6A20
2
SLC6A20 [plasma membrane]
(R-HSA-352058)
SLC6A20 T199M [plasma membrane]
(R-HSA-5660705)
0.718
6
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.718
9
UniProt:Q9Y5W5 WIF1
1
WIF1 [extracellular region]
(R-HSA-3769320)
0.718
6
UniProt:Q9UIJ7 AK3
1
AK3 [mitochondrial matrix]
(R-HSA-1008241)
0.556
3
UniProt:Q9NQS3 NECTIN3
1
PVRL3 [plasma membrane]
(R-HSA-449762)
0.556
3
UniProt:O43463 SUV39H1
1
SUV39H1 [nucleoplasm]
(R-HSA-427517)
0.556
3
UniProt:Q49AN0 CRY2
4
p-S-CRY2 [nucleoplasm]
(R-HSA-400328)
p-S-CRY2 [cytosol]
(R-HSA-400305)
CRY2 [cytosol]
(R-HSA-400255)
Ub-p-S-CRY2 [nucleoplasm]
(R-HSA-517935)
0.556
3
UniProt:Q12837 POU4F2
1
POU4F2 [nucleoplasm]
(R-HSA-6804414)
0.556
3
UniProt:O95363 FARS2
1
FARS2(1-?) [mitochondrial matrix]
(R-HSA-379565)
0.556
3
UniProt:P06850 CRH
1
CRH [extracellular region]
(R-HSA-420146)
0.556
3
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
0.556
3
UniProt:P25490 YY1
1
YY1 [nucleoplasm]
(R-HSA-4086091)
0.556
3
UniProt:Q02548 PAX5
1
PAX5 [nucleoplasm]
(R-HSA-158583)
0.556
3
UniProt:P31785 IL2RG
4
p-Y-IL2RG [cytosol]
(R-HSA-9009721)
IL2RG [endosome]
(R-HSA-8983165)
p-Y-IL2RG [plasma membrane]
(R-HSA-6786103)
IL2RG [plasma membrane]
(R-HSA-449139)
0.556
3
UniProt:Q86YT5 SLC13A5
1
SLC13A5 [plasma membrane]
(R-HSA-433135)
0.556
3
UniProt:Q15274 QPRT
1
QPRT [cytosol]
(R-HSA-197212)
0.556
3
UniProt:Q99572 P2RX7
1
P2RX7 [plasma membrane]
(R-HSA-877215)
0.556
3
UniProt:O43597 SPRY2
8
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-934555)
p-Y55-SPRY2 [cytosol]
(R-HSA-182950)
SPRY2 [plasma membrane]
(R-HSA-182924)
p-S112,S121-SPRY2 [plasma membrane]
(R-HSA-934595)
SPRY2 [cytosol]
(R-HSA-182949)
p-S112,S115-SPRY2 [cytosol]
(R-HSA-1295619)
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-1295629)
p-S111,S120-SPRY2 [cytosol]
(R-HSA-1295590)
0.556
3
UniProt:Q96SQ9 CYP2S1
1
CYP2S1 [endoplasmic reticulum membrane]
(R-HSA-2980785)
0.556
3
UniProt:Q13875 MOBP
1
MOBP [cytosol]
(R-HSA-9022884)
0.556
3
UniProt:Q92570 NR4A3
1
NR4A3 [nucleoplasm]
(R-HSA-8938004)
0.556
3
UniProt:P24592 IGFBP6
1
IGFBP6 [extracellular region]
(R-HSA-381475)
0.556
3
UniProt:O43602 DCX
1
DCX [cytosol]
(R-HSA-430060)
0.556
3
UniProt:Q13330 MTA1
2
SUMO2,3-K509-MTA1 [nucleoplasm]
(R-HSA-3465537)
MTA1 [nucleoplasm]
(R-HSA-3465550)
0.556
3
UniProt:P09603 CSF1
4
CSF1 [endoplasmic reticulum lumen]
(R-HSA-8956778)
CSF1 [extracellular region]
(R-HSA-9009484)
p-CSF1 [endoplasmic reticulum lumen]
(R-HSA-8956881)
CSF1 [plasma membrane]
(R-HSA-389148)
0.556
3
UniProt:Q9UBX3 SLC25A10
1
SLC25A10 [mitochondrial inner membrane]
(R-HSA-372848)
0.556
3
UniProt:P01024 C3
22
C3c alpha' chain fragment 1 precursor [extracellular region]
(R-HSA-976816)
C3d fragment [extracellular region]
(R-HSA-198999)
C3c alpha' chain fragment 2 [extracellular region]
(R-HSA-976818)
C3c alpha' chain fragment 1 [extracellular region]
(R-HSA-3266502)
C3a-desArg [extracellular region]
(R-HSA-8852808)
C3dg [plasma membrane]
(R-HSA-3266505)
C3d [plasma membrane]
(R-HSA-8853248)
C3f [extracellular region]
(R-HSA-976779)
C3 beta chain [plasma membrane]
(R-HSA-977593)
C3c alpha' chain fragment 1 precursor [plasma membrane]
(R-HSA-977595)
C3c alpha' chain fragment 2 [plasma membrane]
(R-HSA-977594)
C3 alpha chain [azurophil granule lumen]
(R-HSA-6799161)
C3 beta chain [azurophil granule lumen]
(R-HSA-6799159)
C3 alpha chain [secretory granule lumen]
(R-HSA-6800982)
C3 beta chain [secretory granule lumen]
(R-HSA-6801014)
p-C3 [endoplasmic reticulum lumen]
(R-HSA-8957056)
C3 [endoplasmic reticulum lumen]
(R-HSA-8956774)
C3 alpha chain [extracellular region]
(R-HSA-166820)
dNQ-C3(672-1663) [extracellular region]
(R-HSA-182452)
C3b alpha' [extracellular region]
(R-HSA-166830)
C3 beta chain [extracellular region]
(R-HSA-166821)
C3a [extracellular region]
(R-HSA-166828)
0.556
3
UniProt:Q9HB63 NTN4
1
NTN4 [plasma membrane]
(R-HSA-561258)
0.556
3
UniProt:Q86WX3 RPS19BP1
1
RPS19BP1 [nucleoplasm]
(R-HSA-3371427)
0.556
3
UniProt:O43559 FRS3
3
FRS3 [plasma membrane]
(R-HSA-191482)
p-5Y-FRS3 [plasma membrane]
(R-HSA-191475)
p-Y-FRS3 [plasma membrane]
(R-HSA-9032427)
0.556
3
UniProt:Q15742 NAB2
1
NAB2 [nucleoplasm]
(R-HSA-9612177)
0.556
3
UniProt:Q14162 SCARF1
2
SCARF1 [endocytic vesicle membrane]
(R-HSA-2239453)
SCARF1 [plasma membrane]
(R-HSA-2197636)
0.556
3
UniProt:P01137 TGFB1
6
TGFB1 [Golgi lumen]
(R-HSA-177108)
TGFB1 [extracellular region]
(R-HSA-170838)
TGFB1(30-390) [Golgi lumen]
(R-HSA-114705)
TGFB1 [plasma membrane]
(R-HSA-5146781)
TGFB1(30-278) [extracellular region]
(R-HSA-2395367)
TGFB1(30-278) [platelet alpha granule lumen]
(R-HSA-65936)
0.556
3
UniProt:Q9Y2T1 AXIN2
4
RibC-AXIN2 [cytosol]
(R-HSA-3640842)
AXIN2 [cytosol]
(R-HSA-3640821)
Ub-RibC-AXIN2 [cytosol]
(R-HSA-3640859)
ub-AXIN2 [cytosol]
(R-HSA-4641131)
0.556
3
UniProt:P42892 ECE1
1
ECE1 [plasma membrane]
(R-HSA-8876866)
0.556
3
UniProt:O60259 KLK8
3
KLK8 [extracellular region]
(R-HSA-8850833)
proKLK8 [extracellular region]
(R-HSA-8850832)
KLK8 propeptide [extracellular region]
(R-HSA-8850829)
0.556
3
UniProt:Q13526 PIN1
2
PIN1 [nucleoplasm]
(R-HSA-936016)
PIN1 [cytosol]
(R-HSA-9626823)
0.556
3
UniProt:P62857 RPS28
2
RPS28 [cytosol]
(R-HSA-72365)
RPS28 [nucleoplasm]
(R-HSA-6791202)
0.556
3
UniProt:P22301 IL10
1
IL10 [extracellular region]
(R-HSA-447125)
0.556
3
UniProt:Q92824 PCSK5
2
PCSK5(115-913) [Golgi lumen]
(R-HSA-166558)
PCSK5 [extracellular region]
(R-HSA-6784682)
0.556
3
UniProt:O95231 VENTX
1
VENTX [nucleoplasm]
(R-HSA-8853887)
0.556
3
UniProt:P20336 RAB3A
9
GGC-RAB3A [cytosol]
(R-HSA-8870429)
GGC-RAB3A [secretory granule membrane]
(R-HSA-8875319)
RAB3A [cytosol]
(R-HSA-8870410)
RAB3A [secretory granule membrane]
(R-HSA-6804968)
RAB3A [clathrin-sculpted acetylcholine transport vesicle membrane]
(R-HSA-379365)
RAB3A [clathrin-sculpted monoamine transport vesicle membrane]
(R-HSA-372512)
RAB3A [clathrin-sculpted glutamate transport vesicle membrane]
(R-HSA-210466)
RAB3A [plasma membrane]
(R-HSA-210461)
RAB3A [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-917743)
0.556
3
UniProt:Q99895 CTRC
1
CTRC [extracellular region]
(R-HSA-5693362)
0.556
3
UniProt:Q15077 P2RY6
1
P2RY6 [plasma membrane]
(R-HSA-417924)
0.556
3
UniProt:Q6PJG9 LRFN4
1
SALM3 [plasma membrane]
(R-HSA-197883)
0.556
3
UniProt:Q9BSD3 RHNO1
1
RHNO1 [nucleoplasm]
(R-HSA-5684880)
0.556
3
UniProt:O75093 SLIT1
1
SLIT1 [extracellular region]
(R-HSA-204359)
0.556
3
UniProt:O60573 EIF4E2
1
EIF4E2 [cytosol]
(R-HSA-1678822)
0.556
3
UniProt:Q08117 TLE5
1
AES [nucleoplasm]
(R-HSA-4648963)
0.556
3
UniProt:Q9BZE9 ASPSCR1
1
ASPSCR1 [cytoplasmic vesicle membrane]
(R-HSA-1449582)
0.556
3
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