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SPRR2E [cytosol]
Stable Identifier
R-HSA-6810839
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Small proline-rich protein 2E, SPR2E_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
CDSN binds the cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Lamellar bodies bind the early cornified envelope (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Cornified envelope:CDSN [plasma membrane] (Homo sapiens)
Cornified envelope [plasma membrane] (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
No FGN-cornified envelope:CDSN [plasma membrane] (Homo sapiens)
No FGN-Cornified envelope [plasma membrane] (Homo sapiens)
No FGN-late cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
Reinforcement of the Cornified Envelope (Homo sapiens)
Early cornified envelope [plasma membrane] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
SPRs [cytosol] (Homo sapiens)
SPRR2E [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22531 SPRR2E
Gene Names
SPRR2E
Chain
chain:1-72
Reference Genes
BioGPS Gene:6704 SPRR2E
COSMIC (genes):SPRR2E SPRR2E
CTD Gene:6704 SPRR2E
dbSNP Gene:6704 SPRR2E
ENSEMBL:ENSG00000203785 SPRR2E
ENSEMBL_homo_sapiens_GENE:ENSG00000203785.9 SPRR2E
HGNC:11265 SPRR2E
KEGG Gene (Homo sapiens):6704 SPRR2E
Monarch:6704 SPRR2E
NCBI Gene:6704 SPRR2E
OMIM:617588 SPRR2E
UCSC:P22531 SPRR2E
Reference Transcript
RefSeq:NM_001024209.3 SPRR2E
Other Identifiers
11735693_x_at
16693370
2435851
2435852
2435861
2435866
2435867
2435870
2435871
2435872
2435873
2435874
2435877
6704
7920214
8180384
8180406
A_23_P148949
A_33_P3325704
GO:0001533
GO:0005198
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0008544
GO:0018149
GO:0030154
GO:0030280
GO:0031424
GO:0036211
GO:0048856
HMNXSV003000801
ILMN_2211018
M20030_f_at
TC01003255.hg
TC01005835.hg
Participates
as a member of
SPRs [cytosol] (Homo sapiens)
Other forms of this molecule
SPRR2E [cornified envelope]
Cross References
RefSeq
NP_001019380.2
OpenTargets
ENSG00000203785
HPA
ENSG00000203785-SPRR2E
GeneCards
P22531
Ensembl
ENSP00000357739
,
ENSG00000203785
,
ENST00000368751
,
ENSP00000357740
,
ENST00000368750
PRO
P22531
Pharos - Targets
P22531
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