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RAB6B [trans-Golgi network membrane]
Stable Identifier
R-HSA-6810985
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
trans-Golgi network membrane
Synonyms
Ras-related protein Rab-6B
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
Fusion of early-endosome derived vesicles at the TGN (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6B [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6B [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1:GARP complex:COG complex:AcM-ARFRP1:GTP:SYS1:MyrG-ARL1:GTP:Golgin dimers:STX6:STX16:VTI1A:VAMP4:early endosome-to-TGN cargo [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6B [trans-Golgi network membrane] (Homo sapiens)
RIC1:RGP1 recruits RAB6:GDP to the TGN (Homo sapiens)
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GDP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6B [trans-Golgi network membrane] (Homo sapiens)
RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Homo sapiens)
RAB6:GDP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GDP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6B [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP:RIC1:RGP1 [trans-Golgi network membrane] (Homo sapiens)
RAB6:GTP [trans-Golgi network membrane] (Homo sapiens)
RAB6 [trans-Golgi network membrane] (Homo sapiens)
RAB6B [trans-Golgi network membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NRW1 RAB6B
Gene Names
RAB6B
Chain
chain:1-208
Reference Genes
BioGPS Gene:51560 RAB6B
COSMIC (genes):RAB6B RAB6B
CTD Gene:51560 RAB6B
dbSNP Gene:51560 RAB6B
ENSEMBL:ENSG00000154917 RAB6B
ENSEMBL_homo_sapiens_GENE:ENSG00000154917.11 RAB6B
HGNC:14902 RAB6B
KEGG Gene (Homo sapiens):51560 RAB6B
Monarch:51560 RAB6B
NCBI Gene:51560 RAB6B
OMIM:615852 RAB6B
UCSC:Q9NRW1 RAB6B
Reference Transcript
RefSeq:NM_016577.3 RAB6B
RefSeq:XM_011512893.2 RAB6B
Other Identifiers
11720504_s_at
11720505_a_at
11720506_a_at
16959363
210127_PM_at
210127_at
221792_PM_at
221792_at
225259_PM_at
225259_at
2696038
2696039
2696041
2696042
2696043
2696044
2696045
2696046
2696047
2696048
2696049
2696050
2696051
2696052
2696053
2696054
2696055
2696056
2696061
2696066
2696068
2696070
2696073
2696085
2696094
2696099
2696100
2696101
36049_at
51560
52959_at
52962_g_at
8090803
A_23_P109974
A_24_P131718
A_24_P475349
A_32_P151191
GE82147
GE88083
GE88084
GO:0000139
GO:0000166
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005793
GO:0005794
GO:0005829
GO:0006886
GO:0006890
GO:0006891
GO:0007030
GO:0008092
GO:0012505
GO:0015031
GO:0016020
GO:0016192
GO:0016787
GO:0030154
GO:0031175
GO:0031410
GO:0031489
GO:0042147
GO:0043226
GO:0048856
GO:0098793
GO:1903292
HMNXSV003007797
Hs.89981.3.A1_3p_at
Hs.89981.3.A2_3p_at
ILMN_1752299
PH_hs_0037781
PH_hs_0041072
TC03001798.hg
g12803378_3p_at
Participates
as a candidate of
RAB6 [trans-Golgi network membrane] (Homo sapiens)
Other forms of this molecule
RAB6B [endoplasmic reticulum membrane]
RAB6B [Golgi membrane]
GGC-RAB6B [trans-Golgi network membrane]
GGC-RAB6B [cytosol]
RAB6B [cytosol]
Inferred To
Homologues of RAB6B [trans-Golgi network membrane]
(Caenorhabditis elegans)
Rab6b [trans-Golgi network membrane]
(Rattus norvegicus)
RAB6B [trans-Golgi network membrane]
(Bos taurus)
RAB6B [trans-Golgi network membrane]
(Caenorhabditis elegans)
RAB6B [trans-Golgi network membrane]
(Dictyostelium discoideum)
RAB6B [trans-Golgi network membrane]
(Drosophila melanogaster)
RAB6B [trans-Golgi network membrane]
(Mus musculus)
RAB6B [trans-Golgi network membrane]
(Saccharomyces cerevisiae)
RAB6B [trans-Golgi network membrane]
(Schizosaccharomyces pombe)
Cross References
RefSeq
XP_011511195.1
,
NP_057661.3
OpenTargets
ENSG00000154917
IntEnz
3.6.5.2
HPA
ENSG00000154917-RAB6B
GeneCards
Q9NRW1
Ensembl
ENST00000543906
,
ENSP00000285208
,
ENSG00000154917
,
ENSP00000437797
,
ENSP00000419381
,
ENST00000486858
,
ENST00000285208
PRO
Q9NRW1
Pharos - Targets
Q9NRW1
PDB
2FFQ
,
2E9S
,
2FE4
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P37173 TGFBR2
9
TGFBR2 Y470D [plasma membrane]
(R-HSA-3640905)
TGFBR2 E526Q [plasma membrane]
(R-HSA-3645770)
TGFBR2 D522N [plasma membrane]
(R-HSA-3640907)
TGFBR2 R528H [plasma membrane]
(R-HSA-3640894)
TGFBR2 R528C [plasma membrane]
(R-HSA-3640899)
TGFBR2 K128Afs*3 [cytosol]
(R-HSA-3642173)
TGFBR2 K128Sfs*35 [cytosol]
(R-HSA-3642166)
NEDD8-K556,K567-TGFBR2 [plasma membrane]
(R-HSA-4332222)
TGFBR2 [plasma membrane]
(R-HSA-170842)
0.527
2
UniProt:P53611 RABGGTB
2
RABGGTB [plasma membrane]
(R-HSA-6801098)
RABGGTB [cytosol]
(R-HSA-8870419)
0.527
3
UniProt:Q92696 RABGGTA
2
RABGGTA [plasma membrane]
(R-HSA-6801086)
RABGGTA [cytosol]
(R-HSA-8870418)
0.527
3
UniProt:P24386 CHM
1
CHM [cytosol]
(R-HSA-6801097)
0.527
3
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