Reactome | PIP4K2C [nucleoplasm]

PIP4K2C [nucleoplasm]

Stable Identifier

R-HSA-6811499

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PIP5K2C

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8TBX8 PIP4K2C

Gene Names

PIP4K2C, PIP5K2C

Chain

initiator methionine:, chain:2-421

Reference Genes

BioGPS Gene:79837 PIP4K2C

COSMIC (genes):PIP4K2C PIP4K2C

CTD Gene:79837 PIP4K2C

dbSNP Gene:79837 PIP4K2C

ENSEMBL:ENSG00000166908 PIP4K2C

HGNC:23786 PIP4K2C

KEGG:hsa:79837 PIP4K2C

Monarch:79837 PIP4K2C

NCBI Gene:79837 PIP4K2C

UCSC:Q8TBX8 PIP4K2C

Reference Transcript

Other Identifiers

11742444_a_at

16753030

218942_PM_at

218942_at

3418304

3418305

3418306

3418308

3418309

3418310

3418311

3418312

3418313

3418314

3418315

3418316

3418317

3418318

3418319

3418320

3418321

3418322

3418323

3418324

3418325

3418330

3418331

3418332

3418333

7956524

79837

90480_at

A_14_P127978

A_23_P162199

GE86697

GE88693

GO:0003824

GO:0005515

GO:0005524

GO:0005654

GO:0005737

GO:0005773

GO:0005776

GO:0005783

GO:0005829

GO:0005886

GO:0006629

GO:0010506

GO:0016301

GO:0016308

GO:0016309

GO:0016740

GO:0042802

GO:0043226

GO:0043229

GO:0046488

GO:0046627

GO:0046854

GO:0052742

GO:0070062

GO:1902635

GO:2000786

HMNXSV003041721

ILMN_1787308

PH_hs_0029213

TC12000535.hg

g13376135_3p_at

Participates

as a component of

Other forms of this molecule

PIP4K2C [cytosol]

Inferred To

ppk-2 [nucleoplasm] (Caenorhabditis elegans)

pip4k2c [nucleoplasm] (Danio rerio)

pip4k2c [nucleoplasm] (Xenopus tropicalis)

PIP4K2C [nucleoplasm] (Bos taurus)

PIP4K2C [nucleoplasm] (Canis familiaris)

PIP4K2C [nucleoplasm] (Dictyostelium discoideum)

PIP4K2C [nucleoplasm] (Plasmodium falciparum)

PIP4K2C [nucleoplasm] (Sus scrofa)

Pip4k2c [nucleoplasm] (Mus musculus)

Pip4k2c [nucleoplasm] (Rattus norvegicus)

Homologues of PIP4K2C [nucleoplasm] (Dictyostelium discoideum)

PIPkinA [nucleoplasm] (Dictyostelium discoideum)

MSS4 [nucleoplasm] (Saccharomyces cerevisiae)

PIP4K [nucleoplasm] (Drosophila melanogaster)

its3 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001139731.1, NP_079055.3, NP_001139732.1, NP_001139730.1

ZINC - World Drugs

PI42C_HUMAN

Guide to Pharmacology - Targets

2163

OpenTargets

ENSG00000166908

ENSEMBL

ENST00000354947, ENST00000540759, ENST00000550465, ENST00000422156, ENSP00000447390, ENSP00000412035, ENSP00000347032, ENSP00000439878

ZINC - FDA approved

PI42C_HUMAN

ZINC - Substances

PI42C_HUMAN

ZINC - Biogenic

PI42C_HUMAN

ZINC target

Q8TBX8

PRO

Q8TBX8

GlyGen

Q8TBX8

PDB

8BQ4, 2GK9, 7QPN, 7QIE

ZINC - Investigational

PI42C_HUMAN

HPA

ENSG00000166908-PIP4K2C

Pharos - Targets

Q8TBX8

ZINC - Predictions - Purchasable

PI42C_HUMAN

HMDB Protein

HMDBP04079

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.527	2
UniProt:Q9UH99 SUN2	1	SUN2 [nuclear envelope] (R-HSA-912382)	0.527	3
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.527	2
UniProt:Q96JC9 EAF1	1	EAF1 [nucleoplasm] (R-HSA-8932787)	0.527	3