ALDH1A1 oxidises GA to DGA

Stable Identifier
R-HSA-6813749
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
D-glyceraldehyde + H2O + NAD(+) => (R)-glycerate + 2 H(+) + NADH
ReviewStatus
5/5
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Retinal dehydrogenase 1 (ALDH1A1 tetramer) is a cytosolic aldehyde dehydrogenase that can oxidise glyceraldehyde (GA) to D-glycerate (DGA) (Yoval-Sanchez et al. 2013). DGA is a metabolite in a minor pathway of fructose catabolism and serine catabolism.
Literature References
PubMed ID Title Journal Year
23444097 New insights into the half-of-the-sites reactivity of human aldehyde dehydrogenase 1A1

Rodriguez-Zavala, JS, Pardo, JP, Yoval-Sánchez, B

Proteins 2013
Participants
Participates
Catalyst Activity

aldehyde dehydrogenase (NAD+) activity of ALDH1A1 tetramer [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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