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SURF4 [Golgi membrane]
Stable Identifier
R-HSA-6813912
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Surfeit locus protein 4
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-dependent Golgi-to-ER retrograde traffic (Homo sapiens)
ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Homo sapiens)
Golgi-to-ER cargo [Golgi membrane] (Homo sapiens)
SURF4:p24 complex [Golgi membrane] (Homo sapiens)
SURF4 [Golgi membrane] (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Homo sapiens)
Golgi-to-ER cargo [Golgi membrane] (Homo sapiens)
SURF4:p24 complex [Golgi membrane] (Homo sapiens)
SURF4 [Golgi membrane] (Homo sapiens)
ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Homo sapiens)
RAB1:GTP:GBF1:ARF:GTP:coatomer:p24 dimers:ARFGAPs:SEC22B:cargo [Golgi membrane] (Homo sapiens)
Golgi-to-ER cargo [Golgi membrane] (Homo sapiens)
SURF4:p24 complex [Golgi membrane] (Homo sapiens)
SURF4 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15260 SURF4
Gene Names
SURF4, SURF-4
Chain
initiator methionine:1, chain:2-269
Reference Genes
BioGPS Gene:6836 SURF4
COSMIC (genes):SURF4 SURF4
CTD Gene:6836 SURF4
dbSNP Gene:6836 SURF4
ENSEMBL:ENSG00000148248 SURF4
ENSEMBL:ENSG00000280951 SURF4
HGNC:11476 SURF4
KEGG Gene (Homo sapiens):6836 SURF4
Monarch:6836 SURF4
NCBI Gene:6836 SURF4
OMIM:185660 SURF4
UCSC:O15260 SURF4
Reference Transcript
RefSeq:NM_001280792.1 SURF4
RefSeq:NM_033161.3 SURF4
RefSeq:NM_001280789.1 SURF4
Other Identifiers
0002340253
11715831_s_at
11715832_s_at
11748521_a_at
11749316_a_at
11750020_s_at
11750021_x_at
17099512
222977_at
222978_at
222979_s_at
3228675
3228676
3228677
3228678
3228679
3228682
3228683
3228685
3228687
3228688
3228697
3228698
4051967
4051968
4051969
4051970
4051971
4051974
4051975
4051977
4051979
4051980
4051991
4051992
65743_at
6836
8164883
A_23_P32052
A_24_P89971
A_33_P3222783
GE79637
GO:0000139
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005764
GO:0005773
GO:0005783
GO:0005789
GO:0005793
GO:0005794
GO:0005829
GO:0005886
GO:0006810
GO:0006890
GO:0007030
GO:0008150
GO:0010638
GO:0016020
GO:0016021
GO:0016192
GO:0030133
GO:0031410
GO:0033116
GO:0035577
GO:0043226
GO:0043312
Hs.284296.0.A3_3p_at
ILMN_1690761
ILMN_1799055
PH_hs_0014739
TC09001688.hg
g5531846_3p_a_at
Participant Of
hasComponent
SURF4:p24 complex [Golgi membrane]
Other forms of this molecule
SURF4 [transport vesicle]
SURF4 [endoplasmic reticulum membrane]
SURF4 [plasma membrane]
SURF4 [azurophil granule membrane]
Inferred To
surf4 [Golgi membrane] (Danio rerio)
ERV29 [Golgi membrane] (Saccharomyces cerevisiae)
Surf4 [Golgi membrane] (Drosophila melanogaster)
Surf4 [Golgi membrane] (Mus musculus)
Surf4 [Golgi membrane] (Rattus norvegicus)
sft-4 [Golgi membrane] (Caenorhabditis elegans)
por [Golgi membrane] (Xenopus tropicalis)
surf1-2 [Golgi membrane] (Dictyostelium discoideum)
Homologues of SURF4 [Golgi membrane] (Xenopus tropicalis)
SURF4 [Golgi membrane] (Canis familiaris)
SURF4 [Golgi membrane] (Gallus gallus)
SURF4 [Golgi membrane] (Plasmodium falciparum)
SURF4 [Golgi membrane] (Schizosaccharomyces pombe)
SURF4 [Golgi membrane] (Sus scrofa)
SURF4 [Golgi membrane] (Xenopus tropicalis)
Cross References
RefSeq
NP_001267718.1
,
NP_149351.1
,
NP_001267721.1
Target Pathogen
5b354852be737e166372ebd0
OpenTargets
ENSG00000148248
GeneCards
O15260
HPA
ENSG00000148248-SURF4
Ensembl
ENST00000485435
,
ENSG00000280951
,
ENST00000629119
,
ENST00000626303
,
ENSP00000486049
,
ENSP00000487537
,
ENSG00000148248
,
ENSP00000419853
,
ENSP00000446061
,
ENST00000371989
,
ENSP00000486869
,
ENST00000629578
,
ENSP00000361057
,
ENST00000545297
PRO
O15260
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q86WV6 STING1
5
TMEM173 [secretory granule membrane]
(R-HSA-6804798)
TMEM173 [plasma membrane]
(R-HSA-6804815)
K63polyUb-STING [endoplasmic reticulum membrane]
(R-HSA-3134805)
K63polyUb-STING [cytoplasmic vesicle membrane]
(R-HSA-3248021)
TMEM173 [endoplasmic reticulum membrane]
(R-HSA-1834940)
0.623
3
UniProt:Q15363 TMED2
5
TMED2 [endoplasmic reticulum membrane]
(R-HSA-5689480)
TMED2 [ER to Golgi transport vesicle membrane]
(R-HSA-5689847)
TMED2 [transport vesicle]
(R-HSA-6808806)
TMED2 [Golgi membrane]
(R-HSA-6808804)
TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-1911531)
0.558
3
UniProt:Q8VCW4
2
Unc93b1 [Golgi membrane]
(R-MMU-1679064)
Unc93b1 [endoplasmic reticulum membrane]
(R-MMU-1678930)
0.499
2
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