EVL:PPL heterodimer binds the inner surface of the plasma membrane

Stable Identifier
R-HSA-6814187
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Envoplakin:periplakin heterodimers (EVPL:PPL) bind the plasma membrane. In vitro, EVPL:PPL can bind lipid vesicles in response to increasing Ca2+, suggesting that translocation and binding to the plasma membrane is regulated by elevation of intracellular Ca2+ (Kalinin et al. 2004).

Literature References
PubMed ID Title Journal Year
15033990 Co-assembly of envoplakin and periplakin into oligomers and Ca(2+)-dependent vesicle binding: implications for cornified cell envelope formation in stratified squamous epithelia

Kalinin, AE, Idler, WW, Marekov, LN, McPhie, P, Bowers, B, Steinert, PM, Steven, AC

J. Biol. Chem. 2004
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