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LCE2D [cytosol]
Stable Identifier
R-HSA-6814300
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Late cornified envelope protein 2D, LCE2D_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Keratinization (Homo sapiens)
Formation of the cornified envelope (Homo sapiens)
CASP14 cleaves filaggrin (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE2D [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE2D [cytosol] (Homo sapiens)
Late envelope proteins bind cornified envelope:CDSN (Homo sapiens)
Late cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE2D [cytosol] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE2D [cytosol] (Homo sapiens)
Plasma membrane resorption (Homo sapiens)
Mature cornified envelope [cornified envelope] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE2D [cytosol] (Homo sapiens)
Mature cornified envelope [plasma membrane] (Homo sapiens)
Late envelope proteins [cytosol] (Homo sapiens)
LCE2D [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q5TA82 LCE2D
Gene Names
LCE2D, LEP12, SPRL1A
Chain
chain:1-110
Reference Genes
BioGPS Gene:353141 LCE2D
COSMIC (genes):LCE2D LCE2D
CTD Gene:353141 LCE2D
dbSNP Gene:353141 LCE2D
ENSEMBL:ENSG00000187223 LCE2D
HGNC:16518 LCE2D
Monarch:353141 LCE2D
NCBI Gene:353141 LCE2D
OMIM:612612 LCE2D
UCSC:Q5TA82 LCE2D
Reference Transcript
RefSeq:NM_178430.3 LCE2D
Other Identifiers
11737573_at
11737574_x_at
16671037
2359351
2359353
2359354
2359355
2359356
2359357
2359364
2359365
2359368
2359372
2359374
353141
7905500
A_14_P200034
A_23_P371284
A_33_P3236568
GE541651
GO:0005515
GO:0008544
GO:0031424
GO:0048856
HMNXSV003001773
ILMN_1656706
PH_hs_0030549
PH_hs_0034083
TC01001231.hg
Participates
as a candidate of
Late envelope proteins [cytosol] (Homo sapiens)
Cross References
ENSEMBL
ENSP00000357773
,
ENST00000368784
OpenTargets
ENSG00000187223
HPA
ENSG00000187223-LCE2D
PRO
Q5TA82
Pharos - Targets
Q5TA82
HMDB Protein
HMDBP07774
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O76003 GLRX3
1
GLRX3 [cytosol]
(R-HSA-5691202)
0.718
6
UniProt:Q7Z3S9 NOTCH2NLA
3
NOTCH2NLA [extracellular region]
(R-HSA-9908935)
NOTCH2NLA(1-?) [extracellular region]
(R-HSA-9911493)
NOTCH2NLA(?-236) [extracellular region]
(R-HSA-9911490)
0.556
3
UniProt:O43597 SPRY2
8
p-S112,S115-SPRY2 [cytosol]
(R-HSA-1295619)
SPRY2 [cytosol]
(R-HSA-182949)
SPRY2 [plasma membrane]
(R-HSA-182924)
p-S112,S121-SPRY2 [plasma membrane]
(R-HSA-934595)
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-934555)
p-S111,S120-SPRY2 [cytosol]
(R-HSA-1295590)
p-Y55,Y227-SPRY2 [plasma membrane]
(R-HSA-1295629)
p-Y55-SPRY2 [cytosol]
(R-HSA-182950)
0.556
3
UniProt:Q92570 NR4A3
1
NR4A3 [nucleoplasm]
(R-HSA-8938004)
0.556
3
UniProt:Q92504 SLC39A7
1
SLC39A7 [endoplasmic reticulum membrane]
(R-HSA-442363)
0.556
3
UniProt:P0DPK4 NOTCH2NLC
1
NOTCH2NLC [extracellular region]
(R-HSA-9908932)
0.556
3
UniProt:P07237 P4HB
3
P4HB [endoplasmic reticulum lumen]
(R-HSA-174692)
p-P4HB [endoplasmic reticulum lumen]
(R-HSA-8956902)
HC53,56-P4HB [endoplasmic reticulum lumen]
(R-HSA-3341287)
0.556
3
UniProt:P49639 HOXA1
1
HOXA1 [nucleoplasm]
(R-HSA-5617464)
0.556
8
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