CBCAP complex binds 7-methylguanosine cap of snRNA

Stable Identifier
R-HSA-6814885
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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As the capped pre-snRNA continues to be elongated, the CBCAP complex comprising NCBP1 (CBP80), NCBP2 (CBP20), SRRT (ARS2) and PHAX binds the 7-methylguanosine cap (Hallais et al. 2013). The CBCAP complex enhances 3' processing of the pre-snRNA (Hallais et al. 2013) and participates in export of the snRNA from the nucleus to the cytosol, where the snRNA is further modified and assembled with proteins into pre-snRNPs.

Literature References
PubMed ID Title Journal Year
24270878 CBC-ARS2 stimulates 3'-end maturation of multiple RNA families and favors cap-proximal processing

Hallais, M, Pontvianne, F, Andersen, PR, Clerici, M, Lener, D, Benbahouche, Nel H, Gostan, T, Vandermoere, F, Robert, MC, Cusack, S, Verheggen, C, Jensen, TH, Bertrand, E

Nat. Struct. Mol. Biol. 2013
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