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RFC3 [nucleoplasm]
Stable Identifier
R-HSA-68431
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
RFC38, Activator 1 38 kDa subunit, Replication factor C 38 kDa subunit, A1 38 kDa subunit, RF-C 38 kDa subunit, Replication factor C subunit 3
Locations in the PathwayBrowser for interactor UniProt:O75525
Expand all
Cell Cycle (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Polymerase switching on the C-strand of the telomere (Homo sapiens)
Formation of the CTF18-RFC(7s) complex (Homo sapiens)
RFC3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P40938 RFC3
Gene Names
RFC3
Chain
chain:1-356
Reference Genes
BioGPS Gene:5983 RFC3
COSMIC (genes):RFC3 RFC3
CTD Gene:5983 RFC3
dbSNP Gene:5983 RFC3
ENSEMBL:ENSG00000133119 RFC3
HGNC:9971 RFC3
KEGG Gene (Homo sapiens):5983 RFC3
Monarch:5983 RFC3
NCBI Gene:5983 RFC3
OMIM:600405 RFC3
UCSC:P40938 RFC3
Reference Transcript
RefSeq:NM_181558.2 RFC3
RefSeq:NM_002915.3 RFC3
Other Identifiers
0000070253
0002190148
0004590025
11718403_at
11718404_at
11754883_a_at
16773946
204127_at
204128_s_at
231119_at
3485075
3485076
3485077
3485078
3485079
3485080
3485081
3485082
3485083
3485084
3485088
3485090
3485091
3485114
39269_at
58785_at
5983
78367_at
7968563
A_14_P116670
A_23_P14193
A_32_P197016
A_33_P3214446
GE57577
GO:0000731
GO:0003674
GO:0003677
GO:0003689
GO:0004386
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005663
GO:0005694
GO:0006259
GO:0006260
GO:0006261
GO:0006271
GO:0006281
GO:0006283
GO:0006296
GO:0006297
GO:0006950
GO:0007049
GO:0007165
GO:0008150
GO:0009058
GO:0016887
GO:0017116
GO:0019985
GO:0031390
GO:0032201
GO:0032508
GO:0032991
GO:0033683
GO:0034641
GO:0042276
GO:0042592
GO:0042769
GO:0043226
GO:0046683
GO:0051276
GO:0070987
GO:1900264
GO:1901796
Hs.111458.0.A1_3p_at
ILMN_1658143
ILMN_1711381
ILMN_1784860
L07541_at
PH_hs_0006329
TC13000119.hg
g12803002_3p_at
g4506488_3p_a_at
Participant Of
input
Formation of the CTF18-RFC(7s) complex
hasComponent
CTF18-RFC(7s) complex [nucleoplasm]
RAD17:RFC [nucleoplasm]
RFC Heteropentamer [nucleoplasm]
Inferred To
RFC3 [nucleoplasm] (Bos taurus)
RFC3 [nucleoplasm] (Canis familiaris)
RFC3 [nucleoplasm] (Gallus gallus)
RFC3 [nucleoplasm] (Plasmodium falciparum)
RFC3 [nucleoplasm] (Sus scrofa)
RFC5 [nucleoplasm] (Saccharomyces cerevisiae)
rfc-3 [nucleoplasm] (Caenorhabditis elegans)
rfc5 [nucleoplasm] (Schizosaccharomyces pombe)
Rfc3 [nucleoplasm] (Mus musculus)
Rfc3 [nucleoplasm] (Rattus norvegicus)
RfC38 [nucleoplasm] (Drosophila melanogaster)
rcbtb2 [nucleoplasm] (Xenopus tropicalis)
rfc3 [nucleoplasm] (Danio rerio)
rfc3 [nucleoplasm] (Dictyostelium discoideum)
Cross References
RefSeq
NP_002906.1
,
NP_853536.2
OpenTargets
ENSG00000133119
GeneCards
P40938
HPA
ENSG00000133119-RFC3
Ensembl
ENSP00000369411
,
ENST00000434425
,
ENST00000380071
,
ENSG00000133119
,
ENSP00000401001
PRO
P40938
PDB
6VVO
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35249 RFC4
1
RFC4 [nucleoplasm]
(R-HSA-68429)
0.77
11
UniProt:Q0VD86 INCA1
0.556
3
UniProt:Q6AI12 ANR40
0.556
3
UniProt:O75525 KHDRBS3
2
p-Y-KHDRSB3 [nucleoplasm]
(R-HSA-8849035)
KHDRSB3 [nucleoplasm]
(R-HSA-8849040)
0.556
3
UniProt:Q5VWX1 KHDRBS2
2
p-Y-KHDRBS2 [nucleoplasm]
(R-HSA-8849031)
KHDRBS2 [nucleoplasm]
(R-HSA-8849028)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
PICK1 [plasma membrane]
(R-HSA-416989)
0.556
3
UniProt:P35251 RFC1
1
RFC1 [nucleoplasm]
(R-HSA-68435)
0.499
3
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