Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
RPA2 [nucleoplasm]
Stable Identifier
R-HSA-68457
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA Replication factor A protein 2 (32kD), RPA32, Replication protein A 32 kDa subunit, RP-A, RF-A, Replication factor-A protein 2
Icon
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G2/M Checkpoints (Homo sapiens)
Activation of ATR in response to replication stress (Homo sapiens)
Binding of ATR-ATRIP to the RPA-ssDNA complex (Homo sapiens)
ATR:ATRIP:RPA:ssDNA signaling complex [nucleoplasm] (Homo sapiens)
RPA complexed to ssDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA complexed to ssDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Recruitment of Rad17-RFC complex to DNA (Homo sapiens)
RPA complexed to ssDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
RPA complexed to ssDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
RPA complexed to ssDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Homo sapiens)
Rad17-RFC complex bound to DNA [nucleoplasm] (Homo sapiens)
RPA complexed to ssDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Stalling of DNA replication fork and RPA binding (Homo sapiens)
RPA complexed to ssDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
G2/M DNA damage checkpoint (Homo sapiens)
ATR phosphorylates TP53 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1/S Transition (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA polymerase epsilon binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Processive synthesis on the C-strand of the telomere (Homo sapiens)
Removal of the Flap Intermediate from the C-strand (Homo sapiens)
RPA binds to the Flap on the C-strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Recruitment of DNA2 endonuclease to the C strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Homo sapiens)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
Formation of meiotic heteroduplex (Homo sapiens)
Meiotic D-loop complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Meiotic single-stranded DNA complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Formation of meiotic holliday junction (Homo sapiens)
Meiotic D-loop complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Meiotic Holliday Junction [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Formation of meiotic single-stranded DNA invasion complex (Homo sapiens)
Meiotic single-stranded DNA complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Resolution of meiotic holliday junction (Homo sapiens)
Meiotic Holliday Junction [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to heat stress (Homo sapiens)
HSF1 activation (Homo sapiens)
HSF1 trimer binds HSE on the target gene (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Regulation of HSF1-mediated heat shock response (Homo sapiens)
RPA1 binds HSF1 (Homo sapiens)
HSF1:RPA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA Repair (Homo sapiens)
Base Excision Repair (Homo sapiens)
Resolution of Abasic Sites (AP sites) (Homo sapiens)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Homo sapiens)
PCNA-Dependent Long Patch Base Excision Repair (Homo sapiens)
FEN1 bound to PCNA and APEX1 cleaves flap ssDNA (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
LIG1 binds APEX1 and PCNA at SSB (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
LIG1 bound to APEX1 and PCNA ligates SSB (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (Homo sapiens)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLD,POLE-mediated DNA strand displacement synthesis (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA Damage Bypass (Homo sapiens)
Recognition of DNA damage by PCNA-containing replication complex (Homo sapiens)
PCNA-containing replication complex binds damaged dsDNA (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP1:WDR48 binds monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Homo sapiens)
Termination of translesion DNA synthesis (Homo sapiens)
POLD,POLE binds deISGylated PCNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLD,POLE complete replication of damaged DNA after TLS (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TRIM25 binds monoUb:164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25 ISGylates monoUb:K164-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
UBE2L6:TRIM25:DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP43 binds ISG:K164,ISG:K168-PCNA (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP43 deISGylates ISG:K164,ISG:K168-PCNA (Homo sapiens)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Translesion Synthesis by POLH (Homo sapiens)
Elongation by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Insertion of correct bases opposite the lesion by POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
SPRTN binds monoUb:K164-PCNA associated with POLH (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Homo sapiens)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLI (Homo sapiens)
POLI incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLZ elongates POLI-incorporated dNMP (Homo sapiens)
POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by POLK (Homo sapiens)
POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLK incorporates dNMP opposite to damaged DNA base (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Translesion synthesis by REV1 (Homo sapiens)
POLZ extends translesion synthesis (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
REV1 binds AP-dsDNA (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
REV1 inserts dCMP opposite to AP sites in DNA (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Homo sapiens)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
D-loop extension by DNA polymerases (Homo sapiens)
PCNA:POLD,POLE,POLH,POLK:RPA:RFC [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC:POLH,POLK [nucleoplasm] (Homo sapiens)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Processing of DNA double-strand break ends (Homo sapiens)
ATR activation at DNA DSBs (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
ATR phosphorylates RPA2 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Association of RPA complexes with ssDNA at resected DNA DSBs (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Binding of ATR:ATRIP to RPA at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
PPP4C:PPP4R2 dephosphorylates RPA2 (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Fanconi Anemia Pathway (Homo sapiens)
ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Homo sapiens)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
The complex of ATR and ATRIP is recruited to ICL-DNA (Homo sapiens)
FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Mismatch Repair (Homo sapiens)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Homo sapiens)
DNA polymerase delta polymerizes DNA across single stranded gap (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA:DNA containing single strand gap [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
EXO1 interacting with MSH2:MSH3 excises DNA strand containing an insertion/deletion loop (IDL) (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA:DNA containing single strand gap [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Homo sapiens)
DNA polymerase delta polymerizes DNA across single stranded gap (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA:DNA containing single strand gap [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA:DNA containing single strand gap [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Nucleotide Excision Repair (Homo sapiens)
Global Genome Nucleotide Excision Repair (GG-NER) (Homo sapiens)
Dual Incision in GG-NER (Homo sapiens)
3'-incision of DNA by ERCC5 (XPG) in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Formation of Incision Complex in GG-NER (Homo sapiens)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Homo sapiens)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Formation of the pre-incision complex in GG-NER (Homo sapiens)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in GG-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Homo sapiens)
Dual incision in TC-NER (Homo sapiens)
3' incision by ERCC5 (XPG) in TC-NER (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Homo sapiens)
TC-NER incision complex [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Homo sapiens)
TC-NER incision complex [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Homo sapiens)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
ERCC5 and RPA bind TC-NER site (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Gap-filling DNA repair synthesis and ligation in TC-NER (Homo sapiens)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Activation of the pre-replicative complex (Homo sapiens)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA polymerase alpha:primase binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
DNA polymerase epsilon binds at the origin (Homo sapiens)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Homo sapiens)
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Synthesis of DNA (Homo sapiens)
DNA strand elongation (Homo sapiens)
Lagging Strand Synthesis (Homo sapiens)
Processive synthesis on the lagging strand (Homo sapiens)
Removal of the Flap Intermediate (Homo sapiens)
RPA binds to the Flap (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Recruitment of Dna2 endonuclease (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Homo sapiens)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Activity through Phosphorylation (Homo sapiens)
ATR phosphorylates TP53 (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Homo sapiens)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Reproduction (Homo sapiens)
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
Formation of meiotic heteroduplex (Homo sapiens)
Meiotic D-loop complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Meiotic single-stranded DNA complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Formation of meiotic holliday junction (Homo sapiens)
Meiotic D-loop complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Meiotic Holliday Junction [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Formation of meiotic single-stranded DNA invasion complex (Homo sapiens)
Meiotic single-stranded DNA complex [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
Resolution of meiotic holliday junction (Homo sapiens)
Meiotic Holliday Junction [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
RPA2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15927 RPA2
Gene Names
RPA2, REPA2, RPA32, RPA34
Chain
chain:1-270
Reference Genes
BioGPS Gene:6118 RPA2
COSMIC (genes):RPA2 RPA2
CTD Gene:6118 RPA2
dbSNP Gene:6118 RPA2
ENSEMBL:ENSG00000117748 RPA2
HGNC:10290 RPA2
KEGG:hsa:6118 RPA2
Monarch:6118 RPA2
NCBI Gene:6118 RPA2
OMIM:179836 RPA2
UCSC:P15927 RPA2
Reference Transcript
RefSeq:NM_001286076.1 RPA2
RefSeq:NM_002946.4 RPA2
RefSeq:NM_001297558.1 RPA2
Other Identifiers
1119_at
11717098_a_at
11749574_a_at
11756187_s_at
16684089
201756_PM_at
201756_at
2403302
2403303
2403304
2403305
2403307
2403308
2403309
2403310
2403311
2403312
2403313
2403314
2403315
2403316
2403317
2403321
6118
7914141
A_23_P86133
A_33_P3334635
GE57527
GO:0000723
GO:0000724
GO:0000781
GO:0000785
GO:0003677
GO:0003684
GO:0003697
GO:0005515
GO:0005634
GO:0005654
GO:0005662
GO:0006260
GO:0006281
GO:0006284
GO:0006289
GO:0006298
GO:0006310
GO:0010569
GO:0016604
GO:0016605
GO:0019899
GO:0019903
GO:0031571
GO:0031625
GO:0032200
GO:0034502
GO:0035861
GO:0042162
GO:0043226
GO:0043229
GO:0098505
GO:2000001
HMNXSV003052134
ILMN_1753582
J05249_at
PH_hs_0004601
TC01002414.hg
g4506584_3p_at
g4506584_3p_x_at
Participates
as a component of
RPA1-4 [nucleoplasm] (Homo sapiens)
RPA heterotrimer [nucleoplasm] (Homo sapiens)
Other forms of this molecule
p-S33-RPA2 [nucleoplasm]
Inferred To
Rpa2 [nucleoplasm]
(Mus musculus)
Rpa2 [nucleoplasm]
(Rattus norvegicus)
rpa-4 [nucleoplasm]
(Caenorhabditis elegans)
RPA2 [nucleoplasm]
(Bos taurus)
RPA2 [nucleoplasm]
(Canis familiaris)
RPA2 [nucleoplasm]
(Drosophila melanogaster)
RPA2 [nucleoplasm]
(Gallus gallus)
RPA2 [nucleoplasm]
(Plasmodium falciparum)
RPA2 [nucleoplasm]
(Sus scrofa)
ssb2 [nucleoplasm]
(Schizosaccharomyces pombe)
RFA2 [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of RPA2 [nucleoplasm]
(Dictyostelium discoideum)
rpa2 [nucleoplasm]
(Danio rerio)
rpa2 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_002937.1
,
NP_001284487.1
,
NP_001273005.1
OpenTargets
ENSG00000117748
ENSEMBL
ENST00000373912
,
ENSP00000363021
,
ENSP00000363015
,
ENST00000373909
,
ENST00000313433
,
ENSP00000363017
HPA
ENSG00000117748-RPA2
PRO
P15927
Pharos - Targets
P15927
GlyGen
P15927
PDB
1Z1D
,
1DPU
,
2PQA
,
1QUQ
,
1L1O
,
2Z6K
,
8RK2
,
3KDF
,
4OU0
,
2PI2
,
4MQV
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27694 RPA1
2
RPA1 [nucleoplasm]
(R-HSA-68461)
polySUMO2,3-K449,K577-RPA1 [nucleoplasm]
(R-HSA-4551644)
0.959
20
UniProt:P23025 XPA
1
XPA [nucleoplasm]
(R-HSA-67437)
0.888
9
UniProt:P13051 UNG
1
UNG [nucleoplasm]
(R-HSA-9817526)
0.667
6
UniProt:P54132 BLM
2
BLM [nucleoplasm]
(R-HSA-174881)
4SUMO2,3-BLM [nucleoplasm]
(R-HSA-4568883)
0.643
6
UniProt:O75419 CDC45
1
CDC45 [nucleoplasm]
(R-HSA-68563)
0.576
4
UniProt:P24863 CCNC
1
CCNC [nucleoplasm]
(R-HSA-212418)
0.556
3
UniProt:Q5UIP0 RIF1
1
RIF1 [nucleoplasm]
(R-HSA-480742)
0.547
2
UniProt:Q14191 WRN
2
WRN [nucleoplasm]
(R-HSA-67387)
monoSUMO1-K356,K496,K898-WRN [nucleoplasm]
(R-HSA-4568904)
0.491
3
UniProt:P51587 BRCA2
20
BRCA2 D2983Ffs*34 [cytosol]
(R-HSA-9709538)
BRCA2 K2555* [cytosol]
(R-HSA-9711337)
BRCA2 N2553Tfs*95 [cytosol]
(R-HSA-9712872)
BRCA2 T2685Hfs*9 [cytosol]
(R-HSA-9712879)
BRCA2 K2674Rfs*2 [cytosol]
(R-HSA-9712610)
BRCA2 S3231* [cytosol]
(R-HSA-9711458)
BRCA2 I2675Dfs*6 [cytosol]
(R-HSA-9712869)
BRCA2 R2625* [cytosol]
(R-HSA-9711482)
BRCA2 E3071* [cytosol]
(R-HSA-9711354)
BRCA2 V2716Wfs*17 [cytosol]
(R-HSA-9712761)
BRCA2 W2586* [cytosol]
(R-HSA-9711487)
BRCA2 P2767Lfs*10 [cytosol]
(R-HSA-9712509)
BRCA2 K3032* [cytosol]
(R-HSA-9711485)
BRCA2 S2835* [cytosol]
(R-HSA-9711345)
BRCA2 Y3006* [cytosol]
(R-HSA-9711222)
BRCA2 L2926* [cytosol]
(R-HSA-9711348)
BRCA2 R3128* [cytosol]
(R-HSA-9711177)
BRCA2 E2599* [cytosol]
(R-HSA-9711304)
BRCA2 E2571* [cytosol]
(R-HSA-9711560)
BRCA2 Y2977* [cytosol]
(R-HSA-9711182)
0.462
3
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text