Reactome | CDT1 [nucleoplasm]

CDT1 [nucleoplasm]

Stable Identifier

R-HSA-68536

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

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Locations in the PathwayBrowser for interactor UniProt:Q14566 MCM6

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External Reference Information

External Reference

UniProt:Q9H211 CDT1

Gene Names

CDT1

Chain

chain:1-546

Reference Genes

BioGPS Gene:81620 CDT1

COSMIC (genes):CDT1 CDT1

CTD Gene:81620 CDT1

dbSNP Gene:81620 CDT1

ENSEMBL:ENSG00000167513 CDT1

HGNC:24576 CDT1

KEGG Gene (Homo sapiens):81620 CDT1

Monarch:81620 CDT1

NCBI Gene:81620 CDT1

OMIM:605525 CDT1

UCSC:Q9H211 CDT1

Reference Transcript

RefSeq:NM_030928.3 CDT1

Other Identifiers

0000510128

11721666_at

11721667_a_at

11721668_at

16821869

209832_s_at

228868_x_at

34510_at

3673691

3673692

3673693

3673694

3673695

3673696

3673697

3673699

3673700

3673702

3673704

3673705

3673706

3673707

3673708

7997839

81620

A_23_P37704

A_24_P176374

A_33_P3386262

GE54632

GO:0000076

GO:0000082

GO:0000083

GO:0000278

GO:0000775

GO:0000776

GO:0000777

GO:0003674

GO:0003677

GO:0003682

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006259

GO:0006260

GO:0007049

GO:0007059

GO:0008150

GO:0009058

GO:0016604

GO:0019899

GO:0022607

GO:0030174

GO:0031334

GO:0033044

GO:0033262

GO:0034641

GO:0035563

GO:0043226

GO:0045740

GO:0051276

GO:0051301

GO:0051315

GO:0051383

GO:0065003

GO:0070182

GO:0071163

GO:0072708

GO:0140014

GO:1902426

GO:1902595

GO:1905341

GO:1905342

GO:2000105

Hs.122908.1.S1_3p_at

ILMN_1651237

PH_hs_0006882

TC16000686.hg

g12007404_3p_a_at

Participant Of

output

hasComponent

input

Other forms of this molecule

CDT1 [cytosol]

Inferred To

cdt1 [nucleoplasm] (Danio rerio)

cdt1 [nucleoplasm] (Schizosaccharomyces pombe)

cdt1 [nucleoplasm] (Xenopus tropicalis)

Cdt1 [nucleoplasm] (Mus musculus)

Cdt1 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of CDT1 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of CDT1 [nucleoplasm] (Saccharomyces cerevisiae)

cdt-1 [nucleoplasm] (Caenorhabditis elegans)

dup [nucleoplasm] (Drosophila melanogaster)

CDT1 [nucleoplasm] (Bos taurus)

CDT1 [nucleoplasm] (Canis familiaris)

CDT1 [nucleoplasm] (Gallus gallus)

CDT1 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_112190.2

OpenTargets

ENSG00000167513

HPA

ENSG00000167513-CDT1

GeneCards

Q9H211

Ensembl

ENSG00000167513, ENST00000301019, ENSP00000301019

PRO

Q9H211

Orphanet

19836

PDB

2LE8, 6QCG, 2WVR

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75496 GMNN	2	GMNN [nucleoplasm] (R-HSA-113554) GMNN [cytosol] (R-HSA-68534)	0.974	21
UniProt:Q14566 MCM6	1	MCM6 [nucleoplasm] (R-HSA-68553)	0.656	4
UniProt:P24941 CDK2	5	p-CDK2 [nucleoplasm] (R-HSA-68370) p-Y15-CDK2 [nucleoplasm] (R-HSA-187905) CDK2 [cytosol] (R-HSA-157440) CDK2 [nucleoplasm] (R-HSA-68365) p-T160-CDK2 [nucleoplasm] (R-HSA-187967)	0.643	3
UniProt:P20248 CCNA2	3	CCNA2 [cytosol] (R-HSA-157444) PolyUb-CCNA2 [nucleoplasm] (R-HSA-6783099) CCNA2 [nucleoplasm] (R-HSA-68905)	0.643	4
UniProt:Q99741 CDC6	4	CDC6 [cytosol] (R-HSA-113566) p-CDC6 [cytosol] (R-HSA-68583) p-CDC6 [nucleoplasm] (R-HSA-5661317) CDC6 [nucleoplasm] (R-HSA-68542)	0.609	3
UniProt:O14777 NDC80	1	NDC80 [cytosol] (R-HSA-375314)	0.567	7
UniProt:P06493 CDK1	10	CDK1 [nucleoplasm] (R-HSA-68889) CDK1 [endoplasmic reticulum membrane] (R-HSA-264424) CDK1 [cytosol] (R-HSA-170075) p-T161-CDK1 [nucleoplasm] (R-HSA-170066) p-T161-CDK1 [cytosol] (R-HSA-157415) p-T14,Y15,T161-CDK1 [cytosol] (R-HSA-170071) p-T14-CDK1 [cytosol] (R-HSA-170064) p-T14-CDK1 [nucleoplasm] (R-HSA-170045) p-T14,Y15,T161-CDK1 [nucleoplasm] (R-HSA-170074) p-T14,T161-CDK1 [nucleoplasm] (R-HSA-170078)	0.527	2
UniProt:Q13309 SKP2	3	SKP2 [cytosol] (R-HSA-975495) SKP2 [nucleoplasm] (R-HSA-975554) PolyUb-SKP2 [nucleoplasm] (R-HSA-9687073)	0.527	2
UniProt:P12004 PCNA	5	K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) SUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) PCNA [nucleoplasm] (R-HSA-68439)	0.499	2

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