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TFDP1 [nucleoplasm]
Stable Identifier
R-HSA-68652
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DP-1, Transcription factor DP-1 (E2F dimerization partner 1)(DRTF1-polypeptide-1) (DRTF1), Transcription factor Dp-1, E2F dimerization partner 1, DRTF1- polypeptide-1, DRTF1
Icon
Locations in the PathwayBrowser for interactor UniProt:Q9UJY5 GGA1
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by E2F6 (Homo sapiens)
E2F6 binds TFDP1 (Homo sapiens)
TFDP1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14186 TFDP1
Gene Names
TFDP1, DP1
Chain
chain:1-410
Reference Genes
BioGPS Gene:7027 TFDP1
COSMIC (genes):TFDP1 TFDP1
CTD Gene:7027 TFDP1
dbSNP Gene:7027 TFDP1
ENSEMBL:ENSG00000198176 TFDP1
ENSEMBL_homo_sapiens_GENE:ENSG00000198176.13 TFDP1
HGNC:11749 TFDP1
KEGG Gene (Homo sapiens):7027 TFDP1
Monarch:7027 TFDP1
NCBI Gene:7027 TFDP1
OMIM:189902 TFDP1
UCSC:Q14186 TFDP1
Reference Transcript
RefSeq:NM_007111.4 TFDP1
RefSeq:XM_005268327.1 TFDP1
RefSeq:XM_005268331.1 TFDP1
Other Identifiers
11725347_a_at
11725348_x_at
11725349_s_at
11748055_x_at
1670_at
16776905
204147_PM_s_at
204147_s_at
212330_PM_at
212330_at
2377917
2377918
2377920
3502712
3502713
3502714
3502719
3502739
3502751
3502763
3502765
3502766
3502768
3502769
3502770
3502773
3502775
3502779
3502785
3502786
3502787
3502788
3502789
3502790
3502791
3502792
3502793
3635028
3635033
3635034
3635036
3635038
37757_at
7027
7970317
A_32_P199301
A_33_P3384452
GE57682
GO:0000278
GO:0000785
GO:0000977
GO:0000981
GO:0000987
GO:0001228
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0007049
GO:0008544
GO:0012501
GO:0019904
GO:0035189
GO:0043226
GO:0043276
GO:0045893
GO:0045944
GO:0048856
GO:0051091
GO:0051726
GO:0070345
GO:0090575
GO:0140110
GO:0140297
GO:1900087
GO:2000278
HMNXSV003048800
Hs.79353.2.A1_3p_at
ILMN_1661717
ILMN_2117987
L23959_at
PH_hs_0004593
PH_hs_0031354
TC13000426.hg
TC13001318.hg
g6005899_3p_s_at
Participates
as an input of
E2F6 binds TFDP1 (Homo sapiens)
as a component of
E2F6:TFDP1 [nucleoplasm] (Homo sapiens)
as a candidate of
(TFDP1,TFDP2) [nucleoplasm] (Homo sapiens)
as a member of
TFDP1,TFDP2 [nucleoplasm] (Homo sapiens)
Inferred To
TFDP1 [nucleoplasm]
(Bos taurus)
TFDP1 [nucleoplasm]
(Canis familiaris)
TFDP1 [nucleoplasm]
(Gallus gallus)
TFDP1 [nucleoplasm]
(Sus scrofa)
tfdp1 [nucleoplasm]
(Xenopus tropicalis)
dpl-1 [nucleoplasm]
(Caenorhabditis elegans)
tfdp2 [nucleoplasm]
(Dictyostelium discoideum)
tfdp1a [nucleoplasm]
(Danio rerio)
Dp [nucleoplasm]
(Drosophila melanogaster)
Tfdp1 [nucleoplasm]
(Mus musculus)
Tfdp1 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
XP_005268388.1
,
XP_005268384.1
,
NP_009042.1
OpenTargets
ENSG00000198176
GeneCards
Q14186
HPA
ENSG00000198176-TFDP1
Ensembl
ENSG00000198176
,
ENSP00000364519
,
ENST00000375370
PRO
Q14186
Pharos - Targets
Q14186
PDB
2AZE
,
5GOW
,
5TUV
,
5TUU
Interactors (30)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75461 E2F6
2
E2F6 [nucleoplasm]
(R-HSA-8953089)
p-S12-E2F6 [nucleoplasm]
(R-HSA-9007536)
0.953
24
UniProt:Q01094 E2F1
2
E2F1 [nucleoplasm]
(R-HSA-68639)
p-E2F1 [nucleoplasm]
(R-HSA-187911)
0.95
17
UniProt:Q16254 E2F4
1
E2F4 [nucleoplasm]
(R-HSA-68664)
0.806
7
UniProt:P61244 MAX
1
MAX [nucleoplasm]
(R-HSA-3006627)
0.773
7
UniProt:P06400 RB1
20
RB1 R661W [nucleoplasm]
(R-HSA-9659801)
RB1 C706F [nucleoplasm]
(R-HSA-9659812)
RB1 N480del [nucleoplasm]
(R-HSA-9659792)
RB1 C706Y [nucleoplasm]
(R-HSA-9659821)
RB1 R661Q [nucleoplasm]
(R-HSA-9659807)
RB1 I703_E737del [nucleoplasm]
(R-HSA-9661065)
RB1 R830_G887del [cytosol]
(R-HSA-9661059)
RB1 K791* [cytosol]
(R-HSA-9662284)
RB1 Q176* [cytosol]
(R-HSA-9661774)
RB1 S114* [cytosol]
(R-HSA-9661775)
RB1 K765* [cytosol]
(R-HSA-9662281)
RB1 W99* [cytosol]
(R-HSA-9661769)
RB1 S149* [cytosol]
(R-HSA-9661770)
RB1 E166* [cytosol]
(R-HSA-9661767)
RB1 G100* [cytosol]
(R-HSA-9661763)
RB1 E125* [cytosol]
(R-HSA-9661784)
RB1 Q121* [cytosol]
(R-HSA-9661780)
RB1 E184* [cytosol]
(R-HSA-9661781)
RB1 E137* [cytosol]
(R-HSA-9661782)
RB1 K745* [cytosol]
(R-HSA-9662288)
0.744
6
UniProt:Q9BYE7 PCGF6
1
PCGF6 [nucleoplasm]
(R-HSA-8953572)
0.725
6
UniProt:Q14209 E2F2
1
E2F2 [nucleoplasm]
(R-HSA-68649)
0.659
3
UniProt:Q9NX08 COMMD8
2
COMMD8 [nucleoplasm]
(R-HSA-8955102)
COMMD8 [cytosol]
(R-HSA-8955107)
0.643
4
UniProt:Q969R5 L3MBTL2
2
L3MBTL2 [nucleoplasm]
(R-HSA-6804477)
polySUMO2-K675,K700-L3MBTL2 [nucleoplasm]
(R-HSA-6804480)
0.643
6
UniProt:O75496 GMNN
2
GMNN [nucleoplasm]
(R-HSA-113554)
PolyUb-GMNN [nucleoplasm]
(R-HSA-68585)
0.643
3
UniProt:Q13547 HDAC1
2
HDAC1 [nucleoplasm]
(R-HSA-205021)
monoSUMO1-K444,K476-HDAC1 [nucleoplasm]
(R-HSA-4616030)
0.643
4
UniProt:Q8N668 COMMD1
2
COMMD1 [nucleoplasm]
(R-HSA-8955094)
COMMD1 [cytosol]
(R-HSA-8955110)
0.643
4
UniProt:Q8N488 RYBP
1
RYBP [nucleoplasm]
(R-HSA-8937975)
0.643
4
UniProt:Q9H0A8 COMMD4
2
COMMD4 [nucleoplasm]
(R-HSA-8955106)
COMMD4 [cytosol]
(R-HSA-8955111)
0.643
4
UniProt:Q8IY57 YAF2
1
YAF2 [nucleoplasm]
(R-HSA-8937973)
0.643
3
UniProt:Q9UJY5 GGA1
2
GGA1 [early endosome membrane]
(R-HSA-8854136)
GGA1 [endosome membrane]
(R-HSA-5692930)
0.527
2
UniProt:Q06587 RING1
1
RING1 [nucleoplasm]
(R-HSA-389113)
0.527
3
UniProt:Q8IWI9 MGA
1
MGA [nucleoplasm]
(R-HSA-8953093)
0.527
2
UniProt:O00716 E2F3
2
p-E2F3 [nucleoplasm]
(R-HSA-187933)
E2F3 [nucleoplasm]
(R-HSA-68655)
0.527
2
UniProt:P24941 CDK2
5
p-Y15-CDK2 [nucleoplasm]
(R-HSA-187905)
p-CDK2 [nucleoplasm]
(R-HSA-68370)
CDK2 [cytosol]
(R-HSA-157440)
CDK2 [nucleoplasm]
(R-HSA-68365)
p-T160-CDK2 [nucleoplasm]
(R-HSA-187967)
0.527
2
UniProt:Q96GY3 LIN37
1
LIN37 [nucleoplasm]
(R-HSA-389101)
0.527
2
UniProt:P61964 WDR5
1
WDR5 [nucleoplasm]
(R-HSA-1629838)
0.527
3
UniProt:Q8N344 MIER2
0.527
2
UniProt:Q5TKA1 LIN9
1
LIN9 [nucleoplasm]
(R-HSA-389108)
0.527
2
UniProt:Q7Z4G1 COMMD6
2
COMMD6 [nucleoplasm]
(R-HSA-8955097)
COMMD6 [cytosol]
(R-HSA-8955098)
0.527
3
UniProt:Q15329 E2F5
1
E2F5 [nucleoplasm]
(R-HSA-68669)
0.527
2
UniProt:P11142 HSPA8
10
Me3K561-HSPA8 [nucleoplasm]
(R-HSA-8932217)
HSPA8 [secretory granule lumen]
(R-HSA-6801530)
HSPA8 [extracellular region]
(R-HSA-6805936)
HSPA8 [ficolin-1-rich granule lumen]
(R-HSA-6801494)
HSPA8 [nucleoplasm]
(R-HSA-5082380)
HSPA8 [plasma membrane]
(R-HSA-936508)
HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-888599)
HSPA8 [late endosome lumen]
(R-HSA-9631104)
HSPA8 [lysosomal lumen]
(R-HSA-9625182)
HSPA8 [cytosol]
(R-HSA-264476)
0.527
2
UniProt:Q13185 CBX3
1
CBX3 [nucleoplasm]
(R-HSA-427386)
0.527
3
UniProt:O14640 DVL1
4
pp-DVL1 [cytosol]
(R-HSA-3772396)
p-S-DVL1 [cytosol]
(R-HSA-201700)
DVL1 [cytosol]
(R-HSA-201687)
ub-DVL1 [cytosol]
(R-HSA-4641157)
0.463
3
UniProt:Q08999 RBL2
2
RBL2 [nucleoplasm]
(R-HSA-389102)
p-T401,S672,S1035-RBL2 [nucleoplasm]
(R-HSA-1226084)
0.462
4
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