CDK and DDK associate with the Mcm10:pre-replicative complex

Stable Identifier
R-HSA-68918
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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General
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At the beginning of this reaction, 1 molecule of 'Mcm10:active pre-replicative complex', 1 molecule of 'DDK', and 1 molecule of 'CDK' are present. At the end of this reaction, 1 molecule of 'CDK:DDK:Mcm10:pre-replicative complex' is present.

This reaction takes place in the 'nucleus'.

Literature References
PubMed ID Title Journal Year
10523313 Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication.

Jiang, W, McDonald, D, Hope, TJ, Hunter, T

EMBO J 1999
10373557 A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells.

Kumagai, H, Sato, N, Yamada, M, Mahony, D, Seghezzi, W, Lees, E, Arai, K, Masai, H

Mol Cell Biol 1999
Participants
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Orthologous Events
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