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TP53

Stable Identifier
R-HSA-69488
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p53 protein, P53_HUMAN, Cellular tumor antigen p53, Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
TP53, P53
Chain
chain:1-393
Other Identifiers
0005670112
11738335_x_at
11748319_x_at
11748599_a_at
11750514_x_at
11751536_a_at
11751537_x_at
16840732
1939_at
1974_s_at
1A1U
1AIE
1C26
1DT7
1GZH
1H26
1HS5
1JSP
1KZY
1MA3
1OLG
1OLH
1PES
1PET
1SAE
1SAF
1SAK
1SAL
1TSR
1TUP
1UOL
1XQH
1YC5
1YCQ
1YCR
1YCS
201746_at
211300_s_at
2973
2AC0
2ADY
2AHI
2ATA
2B3G
2BIM
2BIN
2BIO
2BIP
2BIQ
2F1X
2FEJ
2FOJ
2FOO
2GS0
2H1L
2H2D
2H2F
2H4F
2H4H
2H4J
2H59
2J0Z
2J10
2J11
2J1W
2J1X
2J1Y
2J1Z
2J20
2J21
2K8F
2L14
2LY4
2MEJ
2MWO
2MWP
2MWY
2MZD
2OCJ
2PCX
2RUK
2VUK
2WGX
2X0U
2X0V
2X0W
2XWR
2YBG
2YDR
2Z5S
2Z5T
31618_at
3743908
3743909
3743912
3743913
3743915
3743917
3743918
3743919
3743920
3743922
3743923
3743924
3743925
3743926
39238
39239
3D05
3D06
3D07
3D08
3D09
3D0A
3DAB
3DAC
3IGK
3IGL
3KMD
3KZ8
3LW1
3OQ5
3PDH
3Q01
3Q05
3Q06
3SAK
3TG5
3TS8
3ZME
4AGL
4AGM
4AGN
4AGP
4AGQ
4BUZ
4BV2
4HFZ
4HJE
4IBQ
4IBS
4IBT
4IBU
4IBV
4IBW
4IBY
4IBZ
4IJT
4KVP
4LO9
4LOE
4LOF
4MZI
4MZR
4QO1
4RP6
4RP7
4X34
4XR8
4ZZJ
51244
5A7B
5AB9
5ABA
5AOI
5AOJ
5AOK
5AOL
5AOM
5BUA
5ECG
5G4M
5G4N
5G4O
5HOU
5HP0
5HPD
5LAP
5LGY
5UN8
7157
72876
8012257
A_23_P26810
A_33_P3315764
AAA59987
AAA59988
AAA59989
AAA61211
AAA61212
AAB39322
AAC12971
AAD28535
AAD28628
AAF36354
AAF36355
AAF36356
AAF36357
AAF36358
AAF36359
AAF36360
AAF36361
AAF36362
AAF36374
AAF36375
AAF36376
AAF36377
AAF36378
AAF36379
AAF36380
AAF36381
AAF36382
AAF63442
AAF63443
AAG28785
AAH03596
AAK76358
AAK76359
AAP30003
AAQ90158
AAR10356
AAR13239
AAV80424
AB082923
ABA29753
ABA29754
ABA29755
ABA29756
ABA29757
ABB80262
ABB80266
AC007421
AC087388
AEX20383
AF135120
AF135121
AF136270
AF136271
AF209128
AF209129
AF209130
AF209131
AF209132
AF209133
AF209134
AF209135
AF209136
AF209148
AF209149
AF209150
AF209151
AF209152
AF209153
AF209154
AF209155
AF209156
AF210308
AF210309
AF210310
AF240684
AF240685
AF307851
AFN61604
AFN61605
AK312568
AY270155
AY359814
AY390341
AY429684
AY838896
BAC16799
BAG35463
BC003596
CAA25652
CAA26306
CAA38095
CAA42626
CAA42627
CAA42628
CAA42629
CAA42630
CAA42631
CAA42632
CAA42633
CAA42634
CAA42635
CAB002973
CAB039238
CAB039239
CAB072876
CCDS11118
CCDS45605
CCDS45606
CCDS73966
CCDS73967
CCDS73968
CCDS73969
CCDS73970
CCDS73971
CH471108
DQ186648
DQ186649
DQ186650
DQ186651
DQ186652
DQ191317
DQ286964
EAW90143
EAW90144
ENSG00000141510
ENSP00000269305
ENSP00000391127
ENSP00000391478
ENSP00000398846
ENSP00000478219
ENSP00000478499
ENSP00000480868
ENSP00000481179
ENSP00000481638
ENSP00000482222
ENSP00000482258
ENSP00000482537
ENSP00000484409
ENST00000269305
ENST00000420246
ENST00000445888
ENST00000455263
ENST00000504290
ENST00000504937
ENST00000510385
ENST00000610292
ENST00000610538
ENST00000617185
ENST00000619485
ENST00000620739
ENST00000622645
EntrezGene:7157
g189478_3p_a_at
g8400737_3p_at
g8400737_3p_x_at
GE58227
GO:0000122
GO:0000228
GO:0000278
GO:0000733
GO:0000790
GO:0000977
GO:0000981
GO:0000988
GO:0000990
GO:0001046
GO:0001071
GO:0001085
GO:0001228
GO:0002020
GO:0002039
GO:0003674
GO:0003677
GO:0003682
GO:0003684
GO:0003700
GO:0003723
GO:0003729
GO:0003730
GO:0005507
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005657
GO:0005669
GO:0005694
GO:0005730
GO:0005737
GO:0005739
GO:0005759
GO:0005783
GO:0005829
GO:0006259
GO:0006284
GO:0006289
GO:0006351
GO:0006355
GO:0006366
GO:0006461
GO:0006464
GO:0006810
GO:0006913
GO:0006914
GO:0006915
GO:0006950
GO:0006974
GO:0006977
GO:0006978
GO:0006983
GO:0007005
GO:0007049
GO:0007050
GO:0007165
GO:0007265
GO:0007275
GO:0007568
GO:0007569
GO:0008104
GO:0008134
GO:0008150
GO:0008219
GO:0008270
GO:0008283
GO:0008285
GO:0008340
GO:0009056
GO:0009058
GO:0010165
GO:0010332
GO:0010628
GO:0012501
GO:0016032
GO:0016363
GO:0016579
GO:0016604
GO:0016605
GO:0019899
GO:0019901
GO:0019903
GO:0022607
GO:0030154
GO:0030308
GO:0030330
GO:0030971
GO:0031065
GO:0031497
GO:0031571
GO:0031625
GO:0032461
GO:0034641
GO:0034644
GO:0035035
GO:0035690
GO:0040007
GO:0042149
GO:0042771
GO:0042802
GO:0042826
GO:0042981
GO:0043065
GO:0043066
GO:0043153
GO:0043161
GO:0043167
GO:0043226
GO:0043234
GO:0043525
GO:0043621
GO:0044212
GO:0044403
GO:0045892
GO:0045893
GO:0045944
GO:0046677
GO:0046827
GO:0046872
GO:0046902
GO:0046982
GO:0047485
GO:0048015
GO:0048147
GO:0048511
GO:0048512
GO:0048856
GO:0050731
GO:0051087
GO:0051097
GO:0051262
GO:0051276
GO:0051289
GO:0051721
GO:0051974
GO:0061024
GO:0065003
GO:0070245
GO:0071158
GO:0071456
GO:0071479
GO:0071480
GO:0072331
GO:0072332
GO:0072717
GO:0090200
GO:0090399
GO:0090403
GO:0097193
GO:0097252
GO:0097718
GO:1900119
GO:1900740
GO:1901796
GO:1902749
GO:1990440
GO:2000379
GO:2001244
H2EHT1
HGNC:11998
HPA051244
Hs.437460
ILMN_1779356
IPR002117
IPR008967
IPR010991
IPR011615
IPR012346
IPR013872
JN900492
JQ694049
JQ694050
K03199
K7PPA8
LRG_321
LRG_321t1
LRG_321t2
LRG_321t3
LRG_321t4
LRG_321t6
LRG_321t8
M13112
M13113
M13114
M13115
M13116
M13117
M13118
M13119
M13120
M13121
M14694
M14695
M22882
M22883
M22884
M22887
M22888
M22894
M22895
M22896
M22897
M22898
M22898_at
MIM:114480
MIM:114500
MIM:114550
MIM:137800
MIM:151623
MIM:191170
MIM:202300
MIM:259500
MIM:260350
MIM:260500
MIM:607107
MIM:614740
NM_000546
NM_001126112
NM_001126113
NM_001126114
NM_001126116
NM_001126118
NM_001276695
NM_001276696
NM_001276698
NM_001276760
NM_001276761
NP_000537
NP_001119584
NP_001119585
NP_001119586
NP_001119588
NP_001119590
NP_001263624
NP_001263625
NP_001263627
NP_001263689
NP_001263690
PF00870
PF07710
PF08563
PH_hs_0019846
PR00386
TC17001094.hg
TC17002468.hg
TP53
TP53-201
TP53-204
TP53-205
TP53-206
TP53-208
TP53-209
TP53-213
TP53-218
TP53-219
TP53-222
TP53-225
TP53-226
TP53-227
U63714
U94788
uc002gij.4
uc002gim.5
uc010cnh.4
uc010cni.4
uc031qyq.2
uc060auo.1
uc060aup.1
uc060auq.1
uc060aur.1
uc060aus.1
uc060aut.1
uc060auu.1
uc060auv.1
UPI000002ED67
UPI000040A8D3
UPI000041E410
UPI0000456A12
UPI00005B7310
UPI00005B7311
UPI00005B7312
UPI0001FDB80B
UPI0001FDB80C
X01405
X02469
X54156
X60011
X60012
X60013
X60014
X60015
X60016
X60017
X60018
X60019
X60020
Participant Of
Other forms of this molecule
Inferred To
Cross References
UCSC human
ZINC - Substances
GeneCards
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.99 Q00987 MDM2_HUMAN 70
0.967 P03070 LT_SV40 22
0.96 P0CG48 UBC_HUMAN 15
0.955 Q93009 UBP7_HUMAN 21
0.945 O15151 MDM4_HUMAN 14
0.942 Q09472 EP300_HUMAN 11
0.941 P04637 P53_HUMAN 11
0.903 EBI-1550784 CDKN1A_HUMAN_GENE 18
0.888 Q96EB6 SIR1_HUMAN 13
0.846 Q13526 PIN1_HUMAN 14
0.845 Q9UER7 DAXX_HUMAN 12
0.84 P06463 VE6_HPV18 5
0.836 Q92793 CBP_HUMAN 9
0.817 Q15672 TWST1_HUMAN 10
0.811 P38646 GRP75_HUMAN 6
0.796 Q07817-1 BCL2L1 18
0.787 P26447 S10A4_HUMAN 7
0.782 Q8WTS6 SETD7_HUMAN 6
0.779 Q96PM5 ZN363_HUMAN 7
0.771 Q13625 ASPP2_HUMAN 5
0.766 Q923E4 SIR1_MOUSE 4
0.761 Q05397 FAK1_HUMAN 13
0.75 P09874 PARP1_HUMAN 5
0.748 Q8WUF5 IASPP_HUMAN 11
0.737 P53350 PLK1_HUMAN 6
0.734 Q13547 HDAC1_HUMAN 7
0.724 P43356 MAGA2_HUMAN 6
0.723 Q14999 CUL7_HUMAN 5
0.721 P29590 PML_HUMAN 4
0.717 Q8NHY2 RFWD2_HUMAN 5
0.716 Q8IWT3 CUL9_HUMAN 4
0.715 Q96KB5 TOPK_HUMAN 7
0.713 Q9H2X6 HIPK2_HUMAN 3
0.712 O14641 DVL2_HUMAN 4
0.702 Q15796 SMAD2_HUMAN 7
0.697 Q9BUJ2 HNRL1_HUMAN 12
0.693 P03126 VE6_HPV16 3
0.692 P04792 HSPB1_HUMAN 3
0.691 O95376 ARI2_HUMAN 5
0.688 Q13362 2A5G_HUMAN 4
0.676 P06748 NPM_HUMAN 6
0.675 Q99986 VRK1_HUMAN 9
0.667 P31947 1433S_HUMAN 4
0.664 P26663-PRO_0000037536 9
0.658 P63279 UBC9_HUMAN 3
0.658 P49841 GSK3B_HUMAN 3
0.656 P17844 DDX5_HUMAN 6
0.656 P30153 2AAA_HUMAN 3
0.654 P38936 CDN1A_HUMAN 3
0.647 Q14191 WRN_HUMAN 5
0.646 O96017 CHK2_HUMAN 3
0.645 Q9BV47 DUS26_HUMAN 9
0.645 Q9Y618 NCOR2_HUMAN 7
0.645 Q86XK2 FBX11_HUMAN 4
0.643 EBI-1550787 MDM2_HUMAN_GENE 3
0.643 P61981 1433G_HUMAN 5
0.639 Q9NPI1 BRD7_HUMAN 8
0.639 P30405 PPIF_HUMAN 4
0.632 Q96FW1 OTUB1_HUMAN 8
0.632 Q9Y3T9 NOC2L_HUMAN 8
0.632 P23396 RS3_HUMAN 4
0.623 P04019 VE6_HPV11 2
0.619 P35232 PHB_HUMAN 6
0.618 P13693 TCTP_HUMAN 5
0.61 Q86TM6 SYVN1_HUMAN 5
0.609 P68400 CSK21_HUMAN 2
0.609 O75925 PIAS1_HUMAN 4
0.608 Q9BWC9 CC106_HUMAN 3
0.602 Q9UHC7 MKRN1_HUMAN 8
0.602 Q05655 KPCD_HUMAN 4
0.602 P89055 P89055_9REOV 6
0.597 Q9P0U4 CXXC1_HUMAN 7
0.597 Q15291 RBBP5_HUMAN 3
0.597 P61964 WDR5_HUMAN 3
0.591 Q8TAQ5 ZN420_HUMAN 4
0.591 P45481 CBP_MOUSE 6
0.591 Q96SB4 SRPK1_HUMAN 3
0.591 Q9UBF1 MAGC2_HUMAN 3
0.591 O60285 NUAK1_HUMAN 5
0.59 Q12888 TP53B_HUMAN 2
0.589 Q9H3D4 P63_HUMAN 5
0.589 O43524 FOXO3_HUMAN 2
0.589 P61978 HNRPK_HUMAN 2
0.589 Q96ST3 SIN3A_HUMAN 2
0.589 P34931 HS71L_HUMAN 2
0.581 P22736 NR4A1_HUMAN 6
0.577 Q96GM8 TOE1_HUMAN 3
0.576 P61289 PSME3_HUMAN 7
0.576 O43847 NRDC_HUMAN 6
0.573 O75928 PIAS2_HUMAN 2
0.573 P11274 BCR_HUMAN 2
0.573 Q16363 LAMA4_HUMAN 2
0.564 P10415 BCL2_HUMAN 5
0.564 Q05086 UBE3A_HUMAN 3
0.564 P06748-1 NPM1 3
0.564 P63104 1433Z_HUMAN 2
0.564 Q9H7Z6 KAT8_HUMAN 2
0.564 P25208 NFYB_HUMAN 6
0.564 P15884 ITF2_HUMAN 2
0.558 P19338 NUCL_HUMAN 2
0.556 O14503 BHE40_HUMAN 5
0.556 Q15424 SAFB1_HUMAN 5
0.556 P46821 MAP1B_HUMAN 6
0.556 P17676 CEBPB_HUMAN 4
0.553 Q96M61 MAGBI_HUMAN 2
0.553 P04183 KITH_HUMAN 2
0.547 P48643 TCPE_HUMAN 2
0.544 P38398 BRCA1_HUMAN 2
0.544 P03120 VE2_HPV16 2
0.544 Q16666-2 IFI16 3
0.544 P55060 XPO2_HUMAN 5
0.544 Q9H9J4-2 USP42 2
0.544 P04731 MT1A_HUMAN 3
0.544 Q9PST7 Q9PST7_XENLA 3
0.537 P11473 VDR_HUMAN 6
0.537 P23511 NFYA_HUMAN 11
0.532 O15047 SET1A_HUMAN 4
0.532 Q9UBL3 ASH2L_HUMAN 5
0.528 P27958-PRO_0000037566 2
0.527 EBI-1550792 TP53I3_HUMAN_GENE 3
0.527 Q8N3Y1 FBXW8_HUMAN 2
0.527 Q9UPR3 SMG5_HUMAN 2
0.527 O75147 OBSL1_HUMAN 2
0.525 EBI-6620336 CD44_HUMAN_GENE 2
0.525 EBI-1799539 CDKN1A_HUMAN_PROMOTE 4
0.524 P26687 TWST1_MOUSE 4
0.524 Q15648 MED1_HUMAN 3
0.524 Q12772 SRBP2_HUMAN 3
0.524 Q08619 IFI5B_MOUSE 2
0.524 O15169 AXIN1_HUMAN 4
0.524 Q15466 NR0B2_HUMAN 3
0.524 Q8IZD2 KMT2E_HUMAN 4
0.524 Q96PU4 UHRF2_HUMAN 3
0.524 P36873-1 PPP1CC 2
0.524 O95863 SNAI1_HUMAN 2
0.524 Q7Z6Z7 HUWE1_HUMAN 3
0.524 Q92841 DDX17_HUMAN 3
0.524 P42858 HD_HUMAN 4
0.524 P61978-2 HNRNPK 2
0.524 Q03701 CEBPZ_HUMAN 2
0.524 Q7L7W2 Q7L7W2_HUMAN 2
0.508 Q9NZN9 AIPL1_HUMAN 2
0.508 Q9BX70 BTBD2_HUMAN 2
0.508 Q8N2W9 PIAS4_HUMAN 2
0.508 Q86Z02 HIPK1_HUMAN 2
0.499 Q8N488 RYBP_HUMAN 3
0.499 Q92993 KAT5_HUMAN 3
0.499 O75970 MPDZ_HUMAN 3
0.499 Q8N9N5 BANP_HUMAN 3
0.499 Q60953-2 PML 3
0.499 Q8TEW0 PARD3_HUMAN 3
0.491 P29590-5 PML 2
0.491 Q8N726 ARF_HUMAN 2
0.488 P16885 PLCG2_HUMAN 2
0.488 O43741 AAKB2_HUMAN 2
0.488 Q96CJ1 EAF2_HUMAN 2
0.488 Q16666 IF16_HUMAN 2
0.488 Q9BYG5 PAR6B_HUMAN 2
0.463 Q8QVZ0 Q8QVZ0_9HEPC 2
0.463 O70445 BARD1_MOUSE 2
0.462 Q7Z2E3 APTX_HUMAN 4
0.462 EBI-1800051 CDKN1A_HUMAN_P53BIND 2