Reactome | p-S15-TP53 [nucleoplasm]

p-S15-TP53 [nucleoplasm]

Stable Identifier

R-HSA-69507

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

p53 ser-15 phosphorylated, Cellular tumor antigen p53, Tumor suppressor p53, Phosphoprotein p53, Antigen NY-CO-13

Icon

Locations in the PathwayBrowser

Expand all

DNA Repair (Homo sapiens)

- DNA Double-Strand Break Repair (Homo sapiens)
  - DNA Double Strand Break Response (Homo sapiens)
    - Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Homo sapiens)
      - ATM phosphorylates TP53 at S15 (Homo sapiens)
        
        p-S15-TP53 Tetramer [nucleoplasm] (Homo sapiens)
        
        p-S15-TP53 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:P04637 TP53

Gene Names

TP53, P53

Chain

chain:1-393

Reference Genes

BioGPS Gene:7157 TP53

COSMIC (genes):TP53 TP53

CTD Gene:7157 TP53

dbSNP Gene:7157 TP53

ENSEMBL:ENSG00000141510 TP53

ENSEMBL_homo_sapiens_GENE:ENSG00000141510 TP53

HGNC:11998 TP53

KEGG Gene (Homo sapiens):7157 TP53

Monarch:7157 TP53

NCBI Gene:7157 TP53

OMIM:191170 TP53

UCSC:P04637 TP53

Reference Transcript

Other Identifiers

0005670112

11738335_x_at

11748319_x_at

11748599_a_at

11750514_x_at

11751536_a_at

11751537_x_at

16840732

1939_at

1974_s_at

1A1U

1AIE

1C26

1DT7

1GZH

1H26

1HS5

1JSP

1KZY

1MA3

1OLG

1OLH

1PES

1PET

1SAE

1SAF

1SAK

1SAL

1TSR

1TUP

1UOL

1XQH

1YC5

1YCQ

1YCR

1YCS

201746_at

211300_s_at

2973

2AC0

2ADY

2AHI

2ATA

2B3G

2BIM

2BIN

2BIO

2BIP

2BIQ

2F1X

2FEJ

2FOJ

2FOO

2GS0

2H1L

2H2D

2H2F

2H4F

2H4H

2H4J

2H59

2J0Z

2J10

2J11

2J1W

2J1X

2J1Y

2J1Z

2J20

2J21

2K8F

2L14

2LY4

2MEJ

2MWO

2MWP

2MWY

2MZD

2OCJ

2PCX

2RUK

2VUK

2WGX

2X0U

2X0V

2X0W

2XWR

2YBG

2YDR

2Z5S

2Z5T

31618_at

3743908

3743909

3743912

3743913

3743915

3743917

3743918

3743919

3743920

3743922

3743923

3743924

3743925

3743926

39238

39239

3D05

3D06

3D07

3D08

3D09

3D0A

3DAB

3DAC

3IGK

3IGL

3KMD

3KZ8

3LW1

3OQ5

3PDH

3Q01

3Q05

3Q06

3SAK

3TG5

3TS8

3ZME

4AGL

4AGM

4AGN

4AGP

4AGQ

4BUZ

4BV2

4HFZ

4HJE

4IBQ

4IBS

4IBT

4IBU

4IBV

4IBW

4IBY

4IBZ

4IJT

4KVP

4LO9

4LOE

4LOF

4MZI

4MZR

4QO1

4RP6

4RP7

4X34

4XR8

4ZZJ

51244

5A7B

5AB9

5ABA

5AOI

5AOJ

5AOK

5AOL

5AOM

5BUA

5ECG

5G4M

5G4N

5G4O

5HOU

5HP0

5HPD

5LAP

5LGY

5MCT

5MCU

5MCV

5MCW

5MF7

5MG7

5MHC

5MOC

5O1A

5O1B

5O1C

5O1D

5O1E

5O1F

5O1G

5O1H

5O1I

5OL0

5UN8

6FF9

6FJ5

7157

72876

8012257

A0A087WT22

A0A087WXZ1

A0A087WZU8

A0A087X1Q1

A0A0U1RQC9

A_23_P26810

A_33_P3315764

AAA59987

AAA59988

AAA59989

AAA61211

AAA61212

AAB39322

AAC12971

AAD28535

AAD28628

AAF36354

AAF36355

AAF36356

AAF36357

AAF36358

AAF36359

AAF36360

AAF36361

AAF36362

AAF36374

AAF36375

AAF36376

AAF36377

AAF36378

AAF36379

AAF36380

AAF36381

AAF36382

AAF63442

AAF63443

AAG28785

AAH03596

AAK76358

AAK76359

AAP30003

AAQ90158

AAR10356

AAR13239

AAV80424

AB082923

ABA29753

ABA29754

ABA29755

ABA29756

ABA29757

ABB80262

ABB80266

AC007421

AC087388

AEX20383

AF135120

AF135121

AF136270

AF136271

AF209128

AF209129

AF209130

AF209131

AF209132

AF209133

AF209134

AF209135

AF209136

AF209148

AF209149

AF209150

AF209151

AF209152

AF209153

AF209154

AF209155

AF209156

AF210308

AF210309

AF210310

AF240684

AF240685

AF307851

AFN61604

AFN61605

AK312568

AY270155

AY359814

AY390341

AY429684

AY838896

AYE20619

BAC16799

BAG35463

BC003596

CAA25652

CAA26306

CAA38095

CAA42626

CAA42627

CAA42628

CAA42629

CAA42630

CAA42631

CAA42632

CAA42633

CAA42634

CAA42635

CAB002973

CAB039238

CAB039239

CAB072876

CCDS11118

CCDS45605

CCDS45606

CCDS73966

CCDS73967

CCDS73968

CCDS73969

CCDS73970

CCDS73971

CH471108

DQ186648

DQ186649

DQ186650

DQ186651

DQ186652

DQ191317

DQ286964

E7EMR6

E7EQX7

E7ESS1

E9PCY9

E9PFT5

EAW90143

EAW90144

ENSG00000141510

ENSP00000269305

ENSP00000391127

ENSP00000391478

ENSP00000398846

ENSP00000478219

ENSP00000478499

ENSP00000480868

ENSP00000481179

ENSP00000481638

ENSP00000482222

ENSP00000482258

ENSP00000482537

ENSP00000484409

ENST00000269305

ENST00000269305.8

ENST00000420246

ENST00000420246.6

ENST00000445888

ENST00000445888.6

ENST00000455263

ENST00000455263.6

ENST00000504290

ENST00000504290.5

ENST00000504937

ENST00000504937.5

ENST00000510385

ENST00000510385.5

ENST00000610292

ENST00000610292.4

ENST00000610538

ENST00000610538.4

ENST00000617185

ENST00000617185.4

ENST00000619485

ENST00000619485.4

ENST00000620739

ENST00000620739.4

ENST00000622645

ENST00000622645.4

EntrezGene:7157

g189478_3p_a_at

g8400737_3p_at

g8400737_3p_x_at

GE58227

GO:0000122

GO:0000733

GO:0000790

GO:0000977

GO:0000978

GO:0000980

GO:0000981

GO:0001046

GO:0001085

GO:0001094

GO:0001228

GO:0001701

GO:0001756

GO:0001836

GO:0002020

GO:0002039

GO:0002309

GO:0002326

GO:0002360

GO:0002376

GO:0002931

GO:0003674

GO:0003677

GO:0003682

GO:0003700

GO:0003723

GO:0003729

GO:0003730

GO:0005507

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005654

GO:0005657

GO:0005667

GO:0005669

GO:0005730

GO:0005737

GO:0005739

GO:0005759

GO:0005783

GO:0005829

GO:0006259

GO:0006284

GO:0006289

GO:0006302

GO:0006355

GO:0006357

GO:0006464

GO:0006606

GO:0006810

GO:0006913

GO:0006914

GO:0006915

GO:0006950

GO:0006974

GO:0006977

GO:0006978

GO:0006979

GO:0006983

GO:0007005

GO:0007049

GO:0007050

GO:0007165

GO:0007179

GO:0007265

GO:0007275

GO:0007369

GO:0007406

GO:0007417

GO:0007507

GO:0007568

GO:0007569

GO:0007623

GO:0008104

GO:0008134

GO:0008150

GO:0008156

GO:0008219

GO:0008270

GO:0008283

GO:0008285

GO:0008340

GO:0009056

GO:0009058

GO:0009299

GO:0009303

GO:0009411

GO:0009651

GO:0009790

GO:0009792

GO:0010165

GO:0010332

GO:0010628

GO:0010629

GO:0010666

GO:0012501

GO:0016032

GO:0016363

GO:0016579

GO:0016604

GO:0016605

GO:0019221

GO:0019899

GO:0019901

GO:0019903

GO:0021549

GO:0022607

GO:0030154

GO:0030234

GO:0030308

GO:0030330

GO:0030512

GO:0030971

GO:0031065

GO:0031497

GO:0031571

GO:0031625

GO:0032461

GO:0032991

GO:0033077

GO:0034103

GO:0034641

GO:0034644

GO:0035033

GO:0035035

GO:0035264

GO:0035690

GO:0035794

GO:0035861

GO:0036003

GO:0040007

GO:0042127

GO:0042149

GO:0042493

GO:0042771

GO:0042802

GO:0042803

GO:0042826

GO:0042981

GO:0043065

GO:0043066

GO:0043153

GO:0043167

GO:0043226

GO:0043504

GO:0043516

GO:0043523

GO:0043525

GO:0043621

GO:0044212

GO:0044403

GO:0045861

GO:0045892

GO:0045893

GO:0045899

GO:0045930

GO:0045944

GO:0046677

GO:0046827

GO:0046872

GO:0046902

GO:0046982

GO:0047485

GO:0048147

GO:0048511

GO:0048512

GO:0048568

GO:0048646

GO:0048856

GO:0050731

GO:0050821

GO:0051087

GO:0051097

GO:0051123

GO:0051262

GO:0051276

GO:0051289

GO:0051402

GO:0051721

GO:0051726

GO:0051974

GO:0060333

GO:0060411

GO:0061024

GO:0061419

GO:0062100

GO:0065003

GO:0070059

GO:0070243

GO:0070245

GO:0070266

GO:0071158

GO:0071456

GO:0071479

GO:0071480

GO:0071494

GO:0071850

GO:0072331

GO:0072332

GO:0072363

GO:0072717

GO:0090200

GO:0090343

GO:0090399

GO:0090403

GO:0097193

GO:0097252

GO:0097371

GO:0097718

GO:1900119

GO:1900740

GO:1901525

GO:1901796

GO:1902108

GO:1902253

GO:1902749

GO:1902895

GO:1903799

GO:1903800

GO:1904024

GO:1990144

GO:1990440

GO:1990841

GO:2000269

GO:2000378

GO:2000379

GO:2000772

GO:2001244

H2EHT1

HGNC:11998

HPA051244

ILMN_1779356

IPR002117

IPR008967

IPR010991

IPR011615

IPR012346

IPR013872

IPR036674

J3KP33

JN900492

JQ694049

JQ694050

K03199

K7PPA8

LRG_321

M13112

M13113

M13114

M13115

M13116

M13117

M13118

M13119

M13120

M13121

M14694

M14695

M22882

M22883

M22884

M22887

M22888

M22894

M22895

M22896

M22897

M22898

M22898_at

MG595988

MIM:114480

MIM:114500

MIM:114550

MIM:137800

MIM:151623

MIM:191170

MIM:202300

MIM:259500

MIM:260350

MIM:260500

MIM:607107

MIM:614740

MIM:618165

NM_000546

NM_001126112

NM_001126113

NM_001126114

NM_001126116

NM_001126118

NM_001276695

NM_001276696

NM_001276698

NM_001276760

NM_001276761

NP_000537

NP_001119584

NP_001119585

NP_001119586

NP_001119588

NP_001119590

NP_001263624

NP_001263625

NP_001263627

NP_001263689

NP_001263690

PF00870

PF07710

PF08563

PF18521

PH_hs_0019846

PR00386

S4R334

TC17001094.hg

TC17002468.hg

TP53

TP53-201

TP53-204

TP53-205

TP53-206

TP53-208

TP53-209

TP53-213

TP53-219

TP53-220

TP53-223

TP53-226

TP53-227

TP53-228

U63714

U94788

UPI000002ED67

UPI000040A8D3

UPI000041E410

UPI0000456A12

UPI00005B7310

UPI00005B7311

UPI00005B7312

UPI0001FDB80B

UPI0001FDB80C

X01405

X02469

X54156

X60011

X60012

X60013

X60014

X60015

X60016

X60017

X60018

X60019

X60020

Participant Of

hasComponent

p-S15-TP53 Tetramer [nucleoplasm]

Other forms of this molecule

Unfolded TP53 [cytosol]

TP53 [cytosol]

PolyUb-TP53 [nucleoplasm]

SUMO2,3-K386-TP53 [nucleoplasm]

Ac-K120,p-S15,S20-TP53 [nucleoplasm]

Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]

Ac-K382,p-S15,S20-TP53 [nucleoplasm]

PolyUb,p-S15,S20-TP53 [nucleoplasm]

p-S315-TP53 [nucleoplasm]

p-S15,S20,S269,T284-TP53 [nucleoplasm]

p-S15,S33,S46-TP53 [nucleoplasm]

p-S15,S392-TP53 [nucleoplasm]

p-T55-TP53 [nucleoplasm]

p-S15,S20,S46-TP53 [nucleoplasm]

p-S15,S20,S392-TP53 [nucleoplasm]

p-S37-TP53 [nucleoplasm]

Me2K-370,382-TP53 [nucleoplasm]

Me1-K372,p-S15,S20-TP53 [nucleoplasm]

p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]

Me-K382,p-S15,S20-TP53 [nucleoplasm]

Me2-K373-TP53 [nucleoplasm]

MeK-370,p-S15,S20-TP53 [nucleoplasm]

PolyUb-TP53 [nucleoplasm]

PolyUb-TP53 [cytosol]

p-S15,S20-TP53 [nucleoplasm]

TP53 [nucleoplasm]

Inferred To

Ghost homologue of p-S15-TP53 [nucleoplasm] (Danio rerio)

phospho-p-S15-TP53 [nucleoplasm] (Bos taurus)

phospho-p-S15-TP53 [nucleoplasm] (Drosophila melanogaster)

phospho-p-S15-TP53 [nucleoplasm] (Mus musculus)

phospho-p-S15-TP53 [nucleoplasm] (Rattus norvegicus)

phospho-p-S15-TP53 [nucleoplasm] (Sus scrofa)

phospho-p-S15-TP53 [nucleoplasm] (Xenopus tropicalis)

Modified Residues

Name

O-phospho-L-serine at 15

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_001263624.1, NP_001263628.1, NP_001263627.1, NP_001119588.1, NP_001119584.1, NP_001119589.1, NP_001119585.1, NP_001119590.1, NP_001263690.1, NP_001263626.1, NP_001263625.1, NP_001119586.1, NP_001263689.1, NP_001119587.1, NP_000537.3

OpenTargets

ENSG00000141510

GeneCards

P04637

ZINC - Substances

P53_HUMAN

ZINC target

P04637

PRO

P04637

ZINC - Predictions - Purchasable

P53_HUMAN

Orphanet

15644

PDB

2L14, 2AC0, 2J1Y, 5O1E, 2J1X, 4HFZ, 2X0W, 5ECG, 5O1H, 4LO9, 2Z5T, 1OLH, 1JSP, 2Z5S, 1GZH, 1OLG, 2FEJ, 2WGX, 4RP6, 3KMD, 4LOE, 5LGY, 3OQ5, 2LY4, 4MZR, 4AGN, 5O1I, 2BIP, 4RP7, 4AGO, 2BIQ, 1H26, 3Q01, 2MEJ, 1TSR, 3ZME, 2VUK, 3Q05, 4IJT, 4BV2, 2AHI, 3Q06, 4BUZ, 5MF7, 1AIE, 2RUK, 2OCJ, 2H59, 4IBQ, 5LAP, 5A7B, 5G4M, 5AOI, 4IBS, 5OL0, 1XQH, 2YBG, 2H4J, 2H1L, 5AOJ, 3D08, 5O1A, 3D07, 1KZY, 3PDH, 4IBV, 5HOU, 5O1D, 5HP0, 1TUP, 5MOC, 2J21, 3SAK, 5XZC, 5AOM, 5MCU, 4IBW, 2B3G, 2MWO, 5MCV, 4IBY, 5O1F, 1MA3, 2J20, 1PET, 5MCW, 4IBZ, 2MZD, 5MHC, 1PES, 4MZI, 5HPD, 2YDR, 3LW1, 4ZZJ, 2J1W, 4AGL, 5O1G, 1C26, 2X0V, 4AGM, 2X0U, 1DT7, 1A1U, 5AB9, 3KZ8, 2GS0, 5UN8, 2ADY, 3D0A, 4QO1, 1YCR, 1SAL, 1YCS, 4X34, 4KVP, 4AGP, 1HS5, 2BIN, 4AGQ, 2J11, 1SAK, 2BIO, 5ABA, 1SAF, 2J0Z, 2H2D, 2H2F, 6FJ5, 1YCQ, 6FF9, 3DAB, 2J10, 1SAE, 3DAC, 2BIM, 2ATA, 2FOO, 2XWR, 3D09, 5G4N, 3TG5, 2FOJ, 1UOL, 3IGK, 4IBT, 5MCT, 3TS8, 5O1B, 2K8F, 2MWY, 5MG7, 3IGL, 1YC5, 5G4O, 5AOK, 4IBU, 2MWP, 4HJE, 2PCX, 5AOL, 2H4H, 3D06, 4LOF, 5BUA, 5O1C, 2F1X, 4XR8, 2J1Z, 3D05, 2H4F

Interactors (189)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q00987 MDM2	11	SUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.994	98
UniProt:P04637 TP53	27	TP53 [cytosol] (R-HSA-8869337) Unfolded TP53 [cytosol] (R-HSA-6813797) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) SUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) Ac-K120,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805656) Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805631) Ac-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-5628868) PolyUb,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6804446) p-S315-TP53 [nucleoplasm] (R-HSA-6805106) p-S15,S20,S269,T284-TP53 [nucleoplasm] (R-HSA-6805133) p-S15,S33,S46-TP53 [nucleoplasm] (R-HSA-6805268) p-S15,S392-TP53 [nucleoplasm] (R-HSA-3222015) p-T55-TP53 [nucleoplasm] (R-HSA-6805400) p-S15,S20,S46-TP53 [nucleoplasm] (R-HSA-6798369) p-S15,S20,S392-TP53 [nucleoplasm] (R-HSA-6805053) p-S37-TP53 [nucleoplasm] (R-HSA-3239022) Me2K-370,382-TP53 [nucleoplasm] (R-HSA-3222242) Me1-K372,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805719) p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm] (R-HSA-6804378) Me-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222124) Me2-K373-TP53 [nucleoplasm] (R-HSA-6805759) MeK-370,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222226) PolyUb-TP53 [nucleoplasm] (R-HSA-6793679) PolyUb-TP53 [cytosol] (R-HSA-6793681) p-S15,S20-TP53 [nucleoplasm] (R-HSA-69683) p-S15-TP53 [nucleoplasm] (R-HSA-69507) TP53 [nucleoplasm] (R-HSA-69488)	0.977	24
UniProt:Q09472 EP300	5	Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) SUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) EP300 [nucleoplasm] (R-HSA-381325)	0.974	21
IntAct:EBI-4399559 UBIQ			0.973	21
UniProt:P03070 LT			0.969	23
UniProt:Q93009 USP7	2	USP7 [nucleoplasm] (R-HSA-3215278) USP7 [cytosol] (R-HSA-8853511)	0.968	22
UniProt:O15151 MDM4	5	PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm] (R-HSA-6804938) PolyUb-MDM4 [nucleoplasm] (R-HSA-6782502) p-S346,S367,S403-MDM4 [nucleoplasm] (R-HSA-349441) p-S403-MDM4 [nucleoplasm] (R-HSA-349461) MDM4 [nucleoplasm] (R-HSA-349430)	0.964	19
UniProt:P0CG48 UBC	316	UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-566-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-338-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-186-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-262-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-414-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-110-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-642-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-488-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130) Ub-443-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783153) Ub-139-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783155) Ub-63-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783094) Ub-671-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783083) Ub-519-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783053) Ub-367-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783105) Ub-215-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783137) Ub-386-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783067) Ub-6-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783122) Ub-310-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783027) Ub-234-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783157) Ub-614-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783063) Ub-462-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783118) Ub-538-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783011) Ub-158-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783140) Ub-82-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783175) Ub-315-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783089) Ub-163-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783091) Ub-543-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783060) Ub-239-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783092) Ub-619-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783125) Ub-467-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783181) Ub-11-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783104) Ub-391-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783170) Ub-87-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783110) Ub-656-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783134) Ub-124-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783120) Ub-428-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783090) Ub-48-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783029) Ub-504-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783113) Ub-200-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783150) Ub-580-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783119) Ub-276-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783183) Ub-352-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783201) Ub-29-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783064) Ub-182-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783097) Ub-486-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783194) Ub-334-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783199) Ub-638-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783188) Ub-106-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783031) Ub-258-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783016) Ub-562-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783172) Ub-410-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783077) Ub-636-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783128) Ub-104-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783032) Ub-256-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783004) Ub-484-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783156) Ub-27-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783022) Ub-332-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783138) Ub-180-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783107) Ub-408-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783108) Ub-560-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783174) N6-glycyl-L-lysine-UBC(457-532) [cytosol] (R-HSA-8869048) N6-glycyl-L-lysine-UBC(609-684) [cytosol] (R-HSA-8869052) N6-glycyl-L-lysine-UBC(229-304) [cytosol] (R-HSA-8869032) N6-glycyl-L-lysine-UBC(533-608) [cytosol] (R-HSA-8869033) N6-glycyl-L-lysine-UBC(153-228) [cytosol] (R-HSA-8869035) N6-glycyl-L-lysine-UBC(305-380) [cytosol] (R-HSA-8869036) N6-glycyl-L-lysine-UBC(77-152) [cytosol] (R-HSA-8869026) N6-glycyl-L-lysine-UBC(1-76) [cytosol] (R-HSA-8869030) N6-glycyl-L-lysine-UBC(381-456) [cytosol] (R-HSA-8869031) Ub-29-UBC(1-76) [cytosol] (R-HSA-5689165) Ub-258-UBC(229-304) [cytosol] (R-HSA-5689167) Ub-334-UBC(305-380) [cytosol] (R-HSA-5689166) Ub-410-UBC(381-456) [cytosol] (R-HSA-5689185) Ub-486-UBC(457-532) [cytosol] (R-HSA-5689176) Ub-562-UBC(533-608) [cytosol] (R-HSA-5689151) Ub-106-UBC(77-152) [cytosol] (R-HSA-5689183) Ub-182-UBC(153-228) [cytosol] (R-HSA-5689169) Ub-638-UBC(609-684) [cytosol] (R-HSA-5689136) Ub-310-UBC(305-380) [cytosol] (R-HSA-5689097) Ub-6-UBC(1-76) [cytosol] (R-HSA-5689091) Ub-462-UBC(457-532) [cytosol] (R-HSA-5689092) Ub-386-UBC(381-456) [cytosol] (R-HSA-5689086) Ub-538-UBC(533-608) [cytosol] (R-HSA-5689104) Ub-158-UBC(153-228) [cytosol] (R-HSA-5689107) Ub-614-UBC(609-684) [cytosol] (R-HSA-5689076) Ub-234-UBC(229-304) [cytosol] (R-HSA-5689110) Ub-82-UBC(77-152) [cytosol] (R-HSA-5689078) Ub-110-UBC(77-152) [cytosol] (R-HSA-5689196) Ub-33-UBC(1-76) [cytosol] (R-HSA-5689134) Ub-488-UBC(457-532) [cytosol] (R-HSA-5689153) Ub-338-UBC(305-380) [cytosol] (R-HSA-5689152) Ub-642-UBC(609-684) [cytosol] (R-HSA-5689218) Ub-414-UBC(381-456) [cytosol] (R-HSA-5689157) Ub-262-UBC(229-304) [cytosol] (R-HSA-5689150) Ub-566-UBC(533-608) [cytosol] (R-HSA-5689205) Ub-186-UBC(153-228) [cytosol] (R-HSA-5689140) adenylatedG608-UBC(533-608) [nucleoplasm] (R-HSA-8852090) adenylatedG380-UBC(305-380) [nucleoplasm] (R-HSA-8852093) adenylatedG532-UBC(457-532) [nucleoplasm] (R-HSA-8852081) adenylatedG304-UBC(229-304) [nucleoplasm] (R-HSA-8852050) adenylatedG152-UBC(77-152) [nucleoplasm] (R-HSA-8852054) adenylatedG684-UBC(609-684) [nucleoplasm] (R-HSA-8852105) adenylatedG228-UBC(153-228) [nucleoplasm] (R-HSA-8852075) adenylatedG76-UBC(1-76) [nucleoplasm] (R-HSA-8852044) adenylatedG456-UBC(381-456) [nucleoplasm] (R-HSA-8852098) UBC [cytosol] (R-HSA-8853531) adenylatedG380-UBC(305-380) [cytosol] (R-HSA-8852062) adenylatedG608-UBC(533-608) [cytosol] (R-HSA-8852052) adenylatedG76-UBC(1-76) [cytosol] (R-HSA-8852053) adenylatedG304-UBC(229-304) [cytosol] (R-HSA-8852117) adenylatedG684-UBC(609-684) [cytosol] (R-HSA-8852118) adenylatedG152-UBC(77-152) [cytosol] (R-HSA-8852087) adenylatedG532-UBC(457-532) [cytosol] (R-HSA-8852045) adenylatedG228-UBC(153-228) [cytosol] (R-HSA-8852111) adenylatedG456-UBC(381-456) [cytosol] (R-HSA-8852069) Ub-428-UBC(381-456) [endoplasmic reticulum membrane] (R-HSA-8943062) Ub-656-UBC(609-684) [endoplasmic reticulum membrane] (R-HSA-8943120) Ub-124-UBC(77-152) [endoplasmic reticulum membrane] (R-HSA-8943129) Ub-48-UBC(1-76) [endoplasmic reticulum membrane] (R-HSA-8943079) Ub-352-UBC(305-380) [endoplasmic reticulum membrane] (R-HSA-8943108) Ub-504-UBC(457-532) [endoplasmic reticulum membrane] (R-HSA-8943075) Ub-276-UBC(229-304) [endoplasmic reticulum membrane] (R-HSA-8943106) Ub-580-UBC(533-608) [endoplasmic reticulum membrane] (R-HSA-8943137) Ub-200-UBC(153-228) [endoplasmic reticulum membrane] (R-HSA-8943087) UBC(77-152) [endoplasmic reticulum membrane] (R-HSA-8943095) UBC(381-456) [endoplasmic reticulum membrane] (R-HSA-8943126) UBC(533-608) [endoplasmic reticulum membrane] (R-HSA-8943061) UBC(609-684) [endoplasmic reticulum membrane] (R-HSA-8943135) UBC(229-304) [endoplasmic reticulum membrane] (R-HSA-8943103) UBC(153-228) [endoplasmic reticulum membrane] (R-HSA-8943068) UBC(1-76) [endoplasmic reticulum membrane] (R-HSA-8943077) UBC(305-380) [endoplasmic reticulum membrane] (R-HSA-8943084) UBC(457-532) [endoplasmic reticulum membrane] (R-HSA-8943112) UBC(1-76) [plasma membrane] (R-HSA-3149469) UBC(457-532) [plasma membrane] (R-HSA-3149468) UBC(153-228) [plasma membrane] (R-HSA-3149467) UBC(609-684) [plasma membrane] (R-HSA-3149466) UBC(77-152) [plasma membrane] (R-HSA-3149465) UBC(229-304) [plasma membrane] (R-HSA-3149464) UBC(533-608) [plasma membrane] (R-HSA-3149462) UBC(381-456) [plasma membrane] (R-HSA-3149459) UBC(305-380) [plasma membrane] (R-HSA-3149458) UBC(1-76) [endosome membrane] (R-HSA-939187) UBC(533-608) [endosome membrane] (R-HSA-939221) UBC(77-152) [endosome membrane] (R-HSA-939161) UBC(305-380) [endosome membrane] (R-HSA-939196) UBC(457-532) [endosome membrane] (R-HSA-939199) UBC(381-456) [endosome membrane] (R-HSA-939166) UBC(153-228) [endosome membrane] (R-HSA-939170) UBC(609-684) [endosome membrane] (R-HSA-939237) UBC(229-304) [endosome membrane] (R-HSA-939172) Ub-256-UBC(229-304) [cytosol] (R-HSA-5689135) Ub-180-UBC(153-228) [cytosol] (R-HSA-5689221) Ub-104-UBC(77-152) [cytosol] (R-HSA-5689189) Ub-484-UBC(457-532) [cytosol] (R-HSA-5689220) Ub-560-UBC(533-608) [cytosol] (R-HSA-5689145) Ub-636-UBC(609-684) [cytosol] (R-HSA-5689144) Ub-332-UBC(305-380) [cytosol] (R-HSA-5689211) Ub-27-UBC(1-76) [cytosol] (R-HSA-5689179) Ub-408-UBC(381-456) [cytosol] (R-HSA-5689182) Ub-87-UBC(77-152) [cytosol] (R-HSA-3095920) Ub-163-UBC(153-228) [cytosol] (R-HSA-3095924) Ub-619-UBC(609-684) [cytosol] (R-HSA-3095925) Ub-467-UBC(457-532) [cytosol] (R-HSA-3095935) Ub-11-UBC(1-76) [cytosol] (R-HSA-3095906) Ub-543-UBC(533-608) [cytosol] (R-HSA-3095912) Ub-391-UBC(381-456) [cytosol] (R-HSA-3095914) Ub-315-UBC(305-380) [cytosol] (R-HSA-3095916) Ub-239-UBC(229-304) [cytosol] (R-HSA-3095919) Ub-519-UBC(457-532) [endosome membrane] (R-HSA-939227) Ub-367-UBC(305-380) [endosome membrane] (R-HSA-939162) Ub-291-UBC(229-304) [endosome membrane] (R-HSA-939226) Ub-443-UBC(381-456) [endosome membrane] (R-HSA-939204) Ub-215-UBC(153-228) [endosome membrane] (R-HSA-939175) Ub-63-UBC(1-76) [endosome membrane] (R-HSA-939174) Ub-595-UBC(533-608) [endosome membrane] (R-HSA-939242) Ub-139-UBC(77-152) [endosome membrane] (R-HSA-939244) Ub-671-UBC(609-684) [endosome membrane] (R-HSA-939183) Ub-291-UBC(229-304) [plasma membrane] (R-HSA-939859) Ub-595-UBC(533-608) [plasma membrane] (R-HSA-939858) Ub-367-UBC(305-380) [plasma membrane] (R-HSA-939861) Ub-63-UBC(1-76) [plasma membrane] (R-HSA-939860) Ub-139-UBC(77-152) [plasma membrane] (R-HSA-939865) Ub-215-UBC(153-228) [plasma membrane] (R-HSA-939864) Ub-519-UBC(457-532) [plasma membrane] (R-HSA-939845) Ub-671-UBC(609-684) [plasma membrane] (R-HSA-939846) Ub-443-UBC(381-456) [plasma membrane] (R-HSA-939848) Ub-215-UBC(153-228) [cytosol] (R-HSA-939186) Ub-139-UBC(77-152) [cytosol] (R-HSA-939254) Ub-595-UBC(533-608) [cytosol] (R-HSA-939198) Ub-291-UBC(229-304) [cytosol] (R-HSA-939173) Ub-367-UBC(305-380) [cytosol] (R-HSA-939206) Ub-671-UBC(609-684) [cytosol] (R-HSA-939241) Ub-63-UBC(1-76) [cytosol] (R-HSA-939176) Ub-519-UBC(457-532) [cytosol] (R-HSA-939212) Ub-443-UBC(381-456) [cytosol] (R-HSA-939182) Ub-408-UBC(381-456) [nucleoplasm] (R-HSA-6782681) Ub-484-UBC(457-532) [nucleoplasm] (R-HSA-6782650) Ub-104-UBC(77-152) [nucleoplasm] (R-HSA-6782651) Ub-256-UBC(229-304) [nucleoplasm] (R-HSA-6782641) Ub-180-UBC(153-228) [nucleoplasm] (R-HSA-6782603) Ub-560-UBC(533-608) [nucleoplasm] (R-HSA-6782637) Ub-27-UBC(1-76) [nucleoplasm] (R-HSA-6782625) Ub-636-UBC(609-684) [nucleoplasm] (R-HSA-6782597) Ub-332-UBC(305-380) [nucleoplasm] (R-HSA-6782630) Ub-638-UBC(609-684) [nucleoplasm] (R-HSA-6782680) Ub-258-UBC(229-304) [nucleoplasm] (R-HSA-6782621) Ub-562-UBC(533-608) [nucleoplasm] (R-HSA-6782672) Ub-410-UBC(381-456) [nucleoplasm] (R-HSA-6782642) Ub-182-UBC(153-228) [nucleoplasm] (R-HSA-6782678) Ub-106-UBC(77-152) [nucleoplasm] (R-HSA-6782602) Ub-334-UBC(305-380) [nucleoplasm] (R-HSA-6782638) Ub-29-UBC(1-76) [nucleoplasm] (R-HSA-6782659) Ub-486-UBC(457-532) [nucleoplasm] (R-HSA-6782661) Ub-671-UBC(609-684) [nucleoplasm] (R-HSA-6782523) Ub-215-UBC(153-228) [nucleoplasm] (R-HSA-6782491) Ub-63-UBC(1-76) [nucleoplasm] (R-HSA-6782492) Ub-443-UBC(381-456) [nucleoplasm] (R-HSA-6782480) Ub-367-UBC(305-380) [nucleoplasm] (R-HSA-6782479) Ub-139-UBC(77-152) [nucleoplasm] (R-HSA-6782496) Ub-519-UBC(457-532) [nucleoplasm] (R-HSA-6782497) Ub-595-UBC(533-608) [nucleoplasm] (R-HSA-6782499) Ub-291-UBC(229-304) [nucleoplasm] (R-HSA-6782500) Ub-48-UBC(1-76) [nucleoplasm] (R-HSA-6782524) Ub-428-UBC(381-456) [nucleoplasm] (R-HSA-6782462) Ub-504-UBC(457-532) [nucleoplasm] (R-HSA-6782512) Ub-276-UBC(229-304) [nucleoplasm] (R-HSA-6782482) Ub-200-UBC(153-228) [nucleoplasm] (R-HSA-6782487) Ub-656-UBC(609-684) [nucleoplasm] (R-HSA-6782474) Ub-580-UBC(533-608) [nucleoplasm] (R-HSA-6782477) Ub-124-UBC(77-152) [nucleoplasm] (R-HSA-6782498) Ub-352-UBC(305-380) [nucleoplasm] (R-HSA-6782467) Ub-467-UBC(457-532) [nucleoplasm] (R-HSA-6782619) Ub-163-UBC(153-228) [nucleoplasm] (R-HSA-6782622) Ub-11-UBC(1-76) [nucleoplasm] (R-HSA-6782609) Ub-87-UBC(77-152) [nucleoplasm] (R-HSA-6782632) Ub-239-UBC(229-304) [nucleoplasm] (R-HSA-6782669) Ub-543-UBC(533-608) [nucleoplasm] (R-HSA-6782594) Ub-391-UBC(381-456) [nucleoplasm] (R-HSA-6782626) Ub-315-UBC(305-380) [nucleoplasm] (R-HSA-6782660) Ub-619-UBC(609-684) [nucleoplasm] (R-HSA-6782662) Ub-186-UBC(153-228) [nucleoplasm] (R-HSA-6782617) Ub-338-UBC(305-380) [nucleoplasm] (R-HSA-6782620) Ub-33-UBC(1-76) [nucleoplasm] (R-HSA-6782653) Ub-110-UBC(77-152) [nucleoplasm] (R-HSA-6782590) Ub-262-UBC(229-304) [nucleoplasm] (R-HSA-6782640) Ub-642-UBC(609-684) [nucleoplasm] (R-HSA-6782674) Ub-566-UBC(533-608) [nucleoplasm] (R-HSA-6782646) Ub-414-UBC(381-456) [nucleoplasm] (R-HSA-6782636) Ub-488-UBC(457-532) [nucleoplasm] (R-HSA-6782599) Ub-82-UBC(77-152) [nucleoplasm] (R-HSA-6782675) Ub-6-UBC(1-76) [nucleoplasm] (R-HSA-6782611) Ub-234-UBC(229-304) [nucleoplasm] (R-HSA-6782677) Ub-158-UBC(153-228) [nucleoplasm] (R-HSA-6782645) Ub-310-UBC(305-380) [nucleoplasm] (R-HSA-6782614) Ub-538-UBC(533-608) [nucleoplasm] (R-HSA-6782664) Ub-462-UBC(457-532) [nucleoplasm] (R-HSA-6782634) Ub-386-UBC(381-456) [nucleoplasm] (R-HSA-6782605) Ub-614-UBC(609-684) [nucleoplasm] (R-HSA-6782657) UBC(229-304) [nucleoplasm] (R-HSA-939857) UBC(381-456) [nucleoplasm] (R-HSA-939856) UBC(305-380) [nucleoplasm] (R-HSA-939863) UBC(457-532) [nucleoplasm] (R-HSA-939862) UBC(533-608) [nucleoplasm] (R-HSA-939866) UBC(77-152) [nucleoplasm] (R-HSA-939869) UBC(609-684) [nucleoplasm] (R-HSA-939868) UBC(1-76) [nucleoplasm] (R-HSA-939871) UBC(153-228) [nucleoplasm] (R-HSA-939853) Ub-124-UBC(77-152) [nucleoplasm] (R-HSA-5683048) Ub-580-UBC(533-608) [nucleoplasm] (R-HSA-5683050) Ub-428-UBC(381-456) [nucleoplasm] (R-HSA-5683041) Ub-276-UBC(229-304) [nucleoplasm] (R-HSA-5683042) Ub-352-UBC(305-380) [nucleoplasm] (R-HSA-5683045) Ub-200-UBC(153-228) [nucleoplasm] (R-HSA-5683046) Ub-48-UBC(1-76) [nucleoplasm] (R-HSA-5683033) Ub-656-UBC(609-684) [nucleoplasm] (R-HSA-5683035) Ub-504-UBC(457-532) [nucleoplasm] (R-HSA-5683039) Ub-671-UBC(609-684) [nucleoplasm] (R-HSA-5682857) Ub-139-UBC(77-152) [nucleoplasm] (R-HSA-5682856) Ub-519-UBC(457-532) [nucleoplasm] (R-HSA-5682848) Ub-63-UBC(1-76) [nucleoplasm] (R-HSA-5682852) Ub-595-UBC(533-608) [nucleoplasm] (R-HSA-5682841) Ub-215-UBC(153-228) [nucleoplasm] (R-HSA-5682840) Ub-443-UBC(381-456) [nucleoplasm] (R-HSA-5682843) Ub-291-UBC(229-304) [nucleoplasm] (R-HSA-5682842) Ub-367-UBC(305-380) [nucleoplasm] (R-HSA-5682837) UBC(457-532) [cytosol] (R-HSA-939184) UBC(1-76) [cytosol] (R-HSA-939188) UBC(381-456) [cytosol] (R-HSA-939191) UBC(229-304) [cytosol] (R-HSA-939192) UBC(153-228) [cytosol] (R-HSA-939258) UBC(609-684) [cytosol] (R-HSA-939165) UBC(77-152) [cytosol] (R-HSA-939164) UBC(305-380) [cytosol] (R-HSA-939232) UBC(533-608) [cytosol] (R-HSA-939239) Ub-48-UBC(1-76) [cytosol] (R-HSA-939219) Ub-656-UBC(609-684) [cytosol] (R-HSA-939255) Ub-428-UBC(381-456) [cytosol] (R-HSA-939190) Ub-504-UBC(457-532) [cytosol] (R-HSA-939257) Ub-580-UBC(533-608) [cytosol] (R-HSA-939256) Ub-276-UBC(229-304) [cytosol] (R-HSA-939207) Ub-124-UBC(77-152) [cytosol] (R-HSA-939209) Ub-200-UBC(153-228) [cytosol] (R-HSA-939179) Ub-352-UBC(305-380) [cytosol] (R-HSA-939181)	0.96	15
UniProt:Q96EB6 SIRT1	1	SIRT1 [nucleoplasm] (R-HSA-427531)	0.957	18
IntAct:EBI-1550784 CDKN1A			0.929	22
UniProt:Q8WTS6 SETD7	1	SETD7 [nucleoplasm] (R-HSA-1183221)	0.922	11
UniProt:Q92793 CREBBP	3	FOXO4-S-S-CREBBP [nucleoplasm] (R-HSA-9617684) SUMO1-K998,K1033,K1056-CREBBP [nucleoplasm] (R-HSA-3927877) CREBBP [nucleoplasm] (R-HSA-193545)	0.911	11
UniProt:Q07817-1 BCL2L1			0.881	26
UniProt:Q12888-1 TP53BP1			0.879	17
UniProt:Q96PM5 RCHY1	2	RCHY1 [nucleoplasm] (R-HSA-5655134) RCHY1 [cytosol] (R-HSA-976013)	0.849	11
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.846	14
UniProt:Q9UER7 DAXX	2	DAXX [nucleoplasm] (R-HSA-3222068) SUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086)	0.845	12
UniProt:P06463 VE6			0.84	5
UniProt:Q13625 TP53BP2	1	TP53BP2 [nucleoplasm] (R-HSA-6799780)	0.829	7
UniProt:Q12888 TP53BP1	3	TP53BP1 [nucleoplasm] (R-HSA-61175) SUMO1-K-TP53BP1 [nucleoplasm] (R-HSA-2997591) p-S25,S1778-TP53BP1 [nucleoplasm] (R-HSA-5683418)	0.829	6
UniProt:Q15672 TWIST1	1	TWIST1 [nucleoplasm] (R-HSA-445442)	0.817	10
UniProt:Q8WUF5 PPP1R13L	1	PPP1R13L [nucleoplasm] (R-HSA-6799738)	0.815	12
UniProt:P38646 HSPA9	6	HSPA9 [mitochondrial inner membrane] (R-HSA-1252206) HSPA9(1-679) [cytosol] (R-HSA-1267964) HSPA9(1-679) [mitochondrial intermembrane space] (R-HSA-1267968) HSPA9 [mitochondrial matrix] (R-HSA-8878802) HSPA9 [cytosol] (R-HSA-5251993) HSPA9 [nucleoplasm] (R-HSA-5252128)	0.811	6
UniProt:P03126 VE6			0.807	5
UniProt:Q9NRG4 SMYD2	1	SMYD2 [nucleoplasm] (R-HSA-3222233)	0.806	6
UniProt:P45481 Crebbp	4	Crebbp [nucleoplasm] (R-MMU-556795) CREBBP [nucleoplasm] (R-MMU-193545) Foxo4-S-S-Crebbp [nucleoplasm] (R-MMU-9617719) Sumo1-K999,K1034,K1057-Crebbp [nucleoplasm] (R-MMU-3927936)	0.797	9
UniProt:P26447 S10A4			0.787	7
UniProt:Q05086 UBE3A	1	UBE3A [cytosol] (R-HSA-976028)	0.77	6
UniProt:Q923E4 Sirt1	2	SIRT1 [nucleoplasm] (R-MMU-427531) Sirt1 [nucleoplasm] (R-MMU-5211238)	0.766	4
UniProt:Q99986 VRK1	2	VRK1 [cytosol] (R-HSA-2995381) VRK1 [nucleoplasm] (R-HSA-2528998)	0.761	11
UniProt:Q05397 PTK2	11	p-Y194,Y397-PTK2 [cytosol] (R-HSA-8874600) p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-HSA-8874613) PTK2(773-1052) [cytosol] (R-HSA-202829) PTK2(1-772) [cytosol] (R-HSA-202827) pY-PTK2 [cytosol] (R-HSA-9632393) p-5Y-PTK2 [cytosol] (R-HSA-5218711) p-5Y,S732-PTK2 [cytosol] (R-HSA-5229006) p-6Y,S732-PTK2 [cytosol] (R-HSA-5218694) PTK2 [cytosol] (R-HSA-201621) p-Y397-PTK2 [cytosol] (R-HSA-354068) p-6Y-PTK2 [cytosol] (R-HSA-354128)	0.761	13
UniProt:P09874 PARP1	4	SUMO1-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551686) SUMO2,3-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551617) PAR-PARP1 [nucleoplasm] (R-HSA-5651713) PARP1 [nucleoplasm] (R-HSA-201568)	0.75	5
UniProt:P09429 HMGB1	5	HMGB1 [ficolin-1-rich granule lumen] (R-HSA-6803291) HMGB1 [secretory granule lumen] (R-HSA-6803337) HC23,45-HMGB1 [extracellular region] (R-HSA-6797422) HMGB1 [nucleoplasm] (R-HSA-266221) HMGB1 [extracellular region] (R-HSA-879382)	0.74	9
UniProt:P63279 UBE2I	8	SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) SUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) UBE2I [cytosol] (R-HSA-4655342) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617)	0.737	5
UniProt:P53350 PLK1	4	p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) PLK1 [nucleoplasm] (R-HSA-156720) p-T210-PLK1 [cytosol] (R-HSA-3000318) PLK1 [cytosol] (R-HSA-164603)	0.737	6
UniProt:Q13547 HDAC1	2	SUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030) HDAC1 [nucleoplasm] (R-HSA-205021)	0.734	7
UniProt:P43356 MAGA2			0.729	7
UniProt:Q9NPI1 BRD7	1	BRD7 [nucleoplasm] (R-HSA-3222092)	0.729	9
UniProt:O14503 BHLHE40	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.728	11
UniProt:Q14999 CUL7	1	CUL7 [cytosol] (R-HSA-535534)	0.723	5
UniProt:P63165 SUMO1	155	TOPORS-G97-SUMO1 [nucleoplasm] (R-HSA-4551623) K14-UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-4085334) PIAS4-G97-SUMO1 [nucleoplasm] (R-HSA-3968375) K2592-RANBP2-G97-SUMO1 [nuclear envelope] (R-HSA-4551627) K2723-RANBP2-G97-SUMO1 [nuclear envelope] (R-HSA-4551737) K2650-RANBP2-G97-SUMO1 [nuclear envelope] (R-HSA-4551591) K196-VHL-G97-SUMO1 [nucleoplasm] (R-HSA-4551630) K171-VHL-G97-SUMO1 [nucleoplasm] (R-HSA-4551632) K159-VHL-G97-SUMO1 [nucleoplasm] (R-HSA-4551713) MDM-G97-SUMO1 [nucleoplasm] (R-HSA-3730829) K575-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-4090305) K804-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-3782561) K750-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-4090298) K676-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-4090396) K554-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-3782555) K779-TRIM28-G97-SUMO1 [nucleoplasm] (R-HSA-3782585) ING2-G97-SUMO1 [nucleoplasm] (R-HSA-4086096) K788-Ncoa2-G97-SUMO1 [nucleoplasm] (R-HSA-4085297) K731-Ncoa2-G97-SUMO1 [nucleoplasm] (R-HSA-4085312) K239-Ncoa2-G97-SUMO1 [nucleoplasm] (R-HSA-4085320) K239-NCOA2-G97-SUMO1 [nucleoplasm] (R-HSA-4085299) K731-NCOA2-G97-SUMO1 [nucleoplasm] (R-HSA-4085290) K788-NCOA2-G97-SUMO1 [nucleoplasm] (R-HSA-4085308) NPM1-G97-SUMO1 [nucleoplasm] (R-HSA-4086019) NCOR2-G97-SUMO1 [nucleoplasm] (R-HSA-3927883) DDX17-G97-SUMO1 [nucleoplasm] (R-HSA-3900210) PARK7-G97-SUMO1 [nucleoplasm] (R-HSA-4085344) K1033-CREBBP-G97-SUMO1 [nucleoplasm] (R-HSA-3927910) K1056-CREBBP-G97-SUMO1 [nucleoplasm] (R-HSA-3927954) K998-CREBBP-G97-SUMO1 [nucleoplasm] (R-HSA-3927822) K1154-NRIP1-G97-SUMO1 [nucleoplasm] (R-HSA-4086067) K756-NRIP1-G97-SUMO1 [nucleoplasm] (R-HSA-4086034) DDX5-G97-SUMO1 [nucleoplasm] (R-HSA-3900212) CASP8AP2-G97-SUMO1 [nucleoplasm] (R-HSA-3927863) K1024-EP300-G97-SUMO1 [nucleoplasm] (R-HSA-3899298) K1020-EP300-G97-SUMO1 [nucleoplasm] (R-HSA-3899290) CTBP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730764) K231-SAFB-G97-SUMO1 [nucleoplasm] (R-HSA-4085364) K294-SAFB-G97-SUMO1 [nucleoplasm] (R-HSA-4085341) K624-MKL1-G97-SUMO1 [nucleoplasm] (R-HSA-3900128) K576-MKL1-G97-SUMO1 [nucleoplasm] (R-HSA-3900225) K499-MKL1-G97-SUMO1 [nucleoplasm] (R-HSA-3900219) K631-DAXX-G97-SUMO1 [nucleoplasm] (R-HSA-4086044) K630-DAXX-G97-SUMO1 [nucleoplasm] (R-HSA-4086012) SIN3A-G97-SUMO1 [nucleoplasm] (R-HSA-4086058) PPARGC1A-G97-SUMO1 [nucleoplasm] (R-HSA-3903014) HIPK2-G97-SUMO1 [nucleoplasm] (R-HSA-4090362) K774-NCOA1-G97-SUMO1 [nucleoplasm] (R-HSA-4085292) K732-NCOA1-G97-SUMO1 [nucleoplasm] (R-HSA-4085278) K538-MBD1-G97-SUMO1 [nucleoplasm] (R-HSA-4090416) K499-MBD1-G97-SUMO1 [nucleoplasm] (R-HSA-4090332) ZNF131-G97-SUMO1 [nucleoplasm] (R-HSA-3730875) K90-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755511) K689-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755446) K863-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755412) K298-NFKB2-G97-SUMO1 [cytosol] (R-HSA-4755505) UBE2I-G97-SUMO1 [cytosol] (R-HSA-4656941) p-S172-IKBKE-G97-SUMO1 [nucleoplasm] (R-HSA-4755408) K309-IKBKG-G97-SUMO1 [nucleoplasm] (R-HSA-4755404) K277-IKBKG-G97-SUMO1 [nucleoplasm] (R-HSA-4755531) NFKBIA-G97-SUMO1 [nucleoplasm] (R-HSA-4656987) RANGAP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730796) AURKA-G97-SUMO1 [cytosol] (R-HSA-4655413) TOP2B-G97-SUMO1 [nucleoplasm] (R-HSA-4641311) TOP1-G97-SUMO1 [nucleoplasm] (R-HSA-4641306) TOP2A-G97-SUMO1 [nucleoplasm] (R-HSA-4641341) K254-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615853) K-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615836) K164-PCNA-G97-SUMO1 [nucleoplasm] (R-HSA-4615951) MDC1-G97-SUMO1 [nucleoplasm] (R-HSA-4570527) STAG2-G97-SUMO1 [nucleoplasm] (R-HSA-3826645) RAD21-G97-SUMO1 [nucleoplasm] (R-HSA-3826574) K411-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568857) K412-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568850) K414-RAD52-G97-SUMO1 [nucleoplasm] (R-HSA-4568900) XRCC4-G97-SUMO1 [nucleoplasm] (R-HSA-4568869) K160-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730884) K490-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730833) K65-PML-G97-SUMO1 [nucleoplasm] (R-HSA-3730879) K203-PARP1-G97-SUMO1 [nucleoplasm] (R-HSA-4551625) K486-PARP1-G97-SUMO1 [nucleoplasm] (R-HSA-4551748) K496-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568906) K898-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568893) K356-WRN-G97-SUMO1 [nucleoplasm] (R-HSA-4568845) RNF168-SUMO1 [nucleoplasm] (R-HSA-4551631) XPC-G97-SUMO1 [nucleoplasm] (R-HSA-4570452) TDG-G97-SUMO1 [nucleoplasm] (R-HSA-4551682) SP100-G97-SUMO1 [nucleoplasm] (R-HSA-3730794) BRCA1-G97-SUMO1 [nucleoplasm] (R-HSA-3730735) RXRA-G97-SUMO1 [nucleoplasm] (R-HSA-4341090) NR5A2-G97-SUMO1 [nucleoplasm] (R-HSA-4755424) K386-AR-G97-SUMO1 [nucleoplasm] (R-HSA-4090321) K520-AR-G97-SUMO1 [nucleoplasm] (R-HSA-4090352) K293-NR3C1-G97-SUMO1 [nucleoplasm] (R-HSA-4341110) K277-NR3C1-G97-SUMO1 [nucleoplasm] (R-HSA-4341057) K389-THRA-G97-SUMO1 [nucleoplasm] (R-HSA-4719415) K283-THRA-G97-SUMO1 [nucleoplasm] (R-HSA-4719434) K399-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341020) K428-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341035) K494-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341093) K89-NR3C2-G97-SUMO1 [nucleoplasm] (R-HSA-4341058) K119-NR5A1-G97-SUMO1 [nucleoplasm] (R-HSA-4546379) K194-NR5A1-G97-SUMO1 [nucleoplasm] (R-HSA-4546380) NR2C1-G97-SUMO1 [nucleoplasm] (R-HSA-4717492) K303-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090373) K266-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090359) K302-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090363) K299-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090349) K268-ESR1-G97-SUMO1 [nucleoplasm] (R-HSA-4090414) K531-PGR-G97-SUMO1 [nucleoplasm] (R-HSA-4341021) K7-PGR-G97-SUMO1 [nucleoplasm] (R-HSA-4341052) K388-PGR-G97-SUMO1 [nucleoplasm] (R-HSA-4341056) K132-NR1H4-G97-SUMO1 [nucleoplasm] (R-HSA-9610527) NR1H4-G97-SUMO1 [nucleoplasm] (R-HSA-4755434) PPARG-G97-SUMO1 [nucleoplasm] (R-HSA-4717445) K395-PPARG-G97-SUMO1 [nucleoplasm] (R-HSA-4717446) PPARA-G97-SUMO1 [nucleoplasm] (R-HSA-4341069) K443-THRB-G97-SUMO1 [nucleoplasm] (R-HSA-4719431) K146-THRB-G97-SUMO1 [nucleoplasm] (R-HSA-4719410) K50-THRB-G97-SUMO1 [nucleoplasm] (R-HSA-4719401) RORA-G97-SUMO1 [nucleoplasm] (R-HSA-4719426) HIC1-G97-SUMO1 [nucleoplasm] (R-HSA-4570544) TP53BP1-G97-SUMO1 [nucleoplasm] (R-HSA-3730731) SP3-G97-SUMO1 [nucleoplasm] (R-HSA-3730646) K423-MITF-G97-SUMO1 [nucleoplasm] (R-HSA-3730755) K289-MITF-G97-SUMO1 [nucleoplasm] (R-HSA-3730738) K25-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968400) K150-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968382) K114-FOXL2-G97-SUMO1 [nucleoplasm] (R-HSA-3968396) HNRNPC-G97-SUMO1 [nucleoplasm] (R-HSA-4570515) K497-NOP58-G97-SUMO1 [nucleoplasm] (R-HSA-4570504) K467-NOP58-G97-SUMO1 [nucleoplasm] (R-HSA-4570462) DNMT3B-G97-SUMO1 [nucleoplasm] (R-HSA-4655444) DNMT3A-G97-SUMO1 [nucleoplasm] (R-HSA-4655383) DNMT1-G97-SUMO1 [nucleoplasm] (R-HSA-4655358) K84-CBX5-G97-SUMO1 [nucleoplasm] (R-HSA-4615838) K-CBX5-G97-SUMO1 [nucleoplasm] (R-HSA-4615955) K476-HDAC1-G97-SUMO1 [nucleoplasm] (R-HSA-4615867) K444-HDAC1-G97-SUMO1 [nucleoplasm] (R-HSA-4616028) CBX4-G97-SUMO1 [nucleoplasm] (R-HSA-4551756) HDAC2-G97-SUMO1 [nucleoplasm] (R-HSA-4616032) SUZ12-G97-SUMO1 [nucleoplasm] (R-HSA-4615961) SATB1-G97-SUMO1 [nucleoplasm] (R-HSA-4615877) HDAC4-G97-SUMO1 [nucleoplasm] (R-HSA-4615956) K1971-CHD3-G97-SUMO1 [nucleoplasm] (R-HSA-8956370) HIST1H4-G97-SUMO1 [nucleoplasm] (R-HSA-4570549) BMI1-G97-SUMO1 [nucleoplasm] (R-HSA-4551654) TFAP2B-G97-SUMO1 [nucleoplasm] (R-HSA-3730839) TFAP2C-G97-SUMO1 [nucleoplasm] (R-HSA-3730823) TFAP2A-1-G97-SUMO1 [nucleoplasm] (R-HSA-3730825) SUMO1(2-101) [nucleoplasm] (R-HSA-2990831) SUMO1 [nucleoplasm] (R-HSA-877304) UBA2-G97-SUMO1 [nucleoplasm] (R-HSA-3730616) UBE2I-G97-SUMO1 [nucleoplasm] (R-HSA-3730622) HERC2-SUMO1 [nucleoplasm] (R-HSA-4551761)	0.722	3
UniProt:P29590 PML	5	SUMO2-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000423) SUMO3-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000386) SUMO1-K65,160,490-PML [nucleoplasm] (R-HSA-3000440) PML [nucleoplasm] (R-HSA-1031706) PML [cytosol] (R-HSA-5624327)	0.721	4
UniProt:Q8NHY2 COP1	3	RFWD2 [nucleoplasm] (R-HSA-349454) p-S387-RFWD2 [cytosol] (R-HSA-349439) p-S387-RFWD2 [nucleoplasm] (R-HSA-349450)	0.717	5
UniProt:Q8IWT3 CUL9	2	G76-NEDD8-K1881-CUL9 [cytosol] (R-HSA-8955921) CUL9 [cytosol] (R-HSA-8855018)	0.716	4
UniProt:Q96KB5 TOPK			0.715	7
UniProt:P13693 TCTP			0.715	7
UniProt:Q16666-2 IFI16			0.715	6
UniProt:Q9H2X6 HIPK2	3	HIPK2 [nucleoplasm] (R-HSA-3215222) p-HIPK2 [nucleoplasm] (R-HSA-6799375) SUMO1-K32-HIPK2 [nucleoplasm] (R-HSA-4090405)	0.713	3
UniProt:O14641 DVL2	5	p-DVL2 [cytosol] (R-HSA-201706) pp-DVL2 [cytosol] (R-HSA-3772398) p-DVL2 [clathrin-coated endocytic vesicle] (R-HSA-5138444) DVL2 [cytosol] (R-HSA-201694) ub-DVL2 [cytosol] (R-HSA-4652689)	0.712	4
UniProt:Q15796 SMAD2	15	p-S465,S467-SMAD2 P305L [cytosol] (R-HSA-3315471) Ub-SMAD2 [cytosol] (R-HSA-6782774) p-S465,S467-SMAD2 D300A [cytosol] (R-HSA-3315064) p-S465,S467-SMAD2 D300N [cytosol] (R-HSA-3315066) p-S465,S467-SMAD2 A354T [cytosol] (R-HSA-3315474) p-S465,S467-SMAD2 P305Q [cytosol] (R-HSA-3315070) p-S465,S467-SMAD2 D300V [cytosol] (R-HSA-3315067) SMAD2 S464* [cytosol] (R-HSA-3304362) p-S465,S467-SMAD2 [nucleoplasm] (R-HSA-3009185) p-S465,S467-SMAD2 [cytosol] (R-HSA-3009186) SMAD2 [cytosol] (R-HSA-3006353) p-T220,S465,S467-SMAD2 [nucleoplasm] (R-HSA-3009189) SMAD2 [nucleoplasm] (R-HSA-3006352) SMAD2 S467P [cytosol] (R-HSA-3304375) SMAD2 S464L [cytosol] (R-HSA-3304383)	0.702	7
UniProt:Q9BUJ2 HNRNPUL1	1	HNRNPUL1 [nucleoplasm] (R-HSA-72106)	0.697	12
UniProt:P04792 HSPB1	3	p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) HSPB1 [cytosol] (R-HSA-450563) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.692	3
UniProt:O95376 ARIH2	1	ARIH2 [cytosol] (R-HSA-975987)	0.691	5
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.69	5
UniProt:Q15291 RBBP5	1	RBBP5 [nucleoplasm] (R-HSA-1629836)	0.69	5
UniProt:Q13362 PPP2R5C	3	PPP2R5C [nucleoplasm] (R-HSA-3008946) p-S337-PPP2R5C [cytosol] (R-HSA-6811447) PPP2R5C [cytosol] (R-HSA-3008954)	0.688	4
UniProt:P02829	11	HSP90AA1 [secretory granule lumen] (R-SCE-6801515) HSP90AB1 [secretory granule lumen] (R-SCE-6801477) HSP90AB1 [extracellular region] (R-SCE-6806463) HSP90AA1 [extracellular region] (R-SCE-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470) HSP90AB1 [ficolin-1-rich granule lumen] (R-SCE-6801491) HSP90AA1 [plasma membrane] (R-SCE-534996) HSP90AB1 [cytosol] (R-SCE-419617) HSP90AA1 [nucleoplasm] (R-SCE-5082401) HSP90AB1 [nucleoplasm] (R-SCE-5082399) HSP90AA1 [cytosol] (R-SCE-192864)	0.678	8
UniProt:Q9NRR4 DROSHA	1	DROSHA [nucleoplasm] (R-HSA-1482510)	0.677	5
UniProt:P06748 NPM1	5	p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [cytosol] (R-HSA-3008211) NPM1 [nucleoplasm] (R-HSA-606320) SUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) SUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.676	6
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.667	4
UniProt:O60341-1 KDM1A			0.664	6
UniProt:P26663-PRO_0000037536			0.664	9
UniProt:P03120 VE2			0.658	3
UniProt:P49841 GSK3B	4	p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B del304-316 [cytosol] (R-HSA-5339682) GSK3B [cytosol] (R-HSA-2997551) GSK3B [nucleoplasm] (R-HSA-2022823)	0.658	3
UniProt:P30153 PPP2R1A	2	PPP2R1A [nucleoplasm] (R-HSA-165968) PPP2R1A [cytosol] (R-HSA-165982)	0.656	3
UniProt:P17844 DDX5	3	SUMO2-K53-DDX5 [nucleoplasm] (R-HSA-3900186) DDX5 [nucleoplasm] (R-HSA-3900136) SUMO1-K53-DDX5 [nucleoplasm] (R-HSA-3900041)	0.656	6
UniProt:P51587 BRCA2	2	p-T3387-BRCA2 [nucleoplasm] (R-HSA-5685241) BRCA2 [nucleoplasm] (R-HSA-50951)	0.655	7
UniProt:P38936 CDKN1A	5	CDKN1A [cytosol] (R-HSA-182512) CDKN1A [nucleoplasm] (R-HSA-182585) p-Y77-CDKN1A [cytosol] (R-HSA-8942601) p-S130-CDKN1A [nucleoplasm] (R-HSA-187857) p-T145-CDKN1A [cytosol] (R-HSA-198614)	0.654	3
UniProt:Q06587 RING1	1	RING1 [nucleoplasm] (R-HSA-389113)	0.65	7
UniProt:Q14191 WRN	2	WRN [nucleoplasm] (R-HSA-67387) SUMO1-K356,K496,K898-WRN [nucleoplasm] (R-HSA-4568904)	0.647	5
UniProt:O96017 CHEK2	3	p-T68-CHEK2 [nucleoplasm] (R-HSA-113825) p-S,3T-CHEK2 [nucleoplasm] (R-HSA-5683784) CHEK2 [nucleoplasm] (R-HSA-113824)	0.646	3
UniProt:Q06330 RBPJ	1	RBPJ [nucleoplasm] (R-HSA-3008668)	0.645	5
UniProt:Q9BV47 DUS26			0.645	9
UniProt:Q9Y618 NCOR2	2	SUMO1-K672-NCOR2 [nucleoplasm] (R-HSA-3927904) NCOR2 [nucleoplasm] (R-HSA-442469)	0.645	7
UniProt:Q86XK2 FBXO11	1	FBXO11 [cytosol] (R-HSA-8955092)	0.645	4
UniProt:Q9UBL3 ASH2L	1	ASH2L [nucleoplasm] (R-HSA-1629834)	0.643	7
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.643	5
IntAct:EBI-1550787 MDM2			0.643	3
UniProt:P30405 PPIF			0.639	4
UniProt:Q6NYC1 JMJD6	1	JMJD6 [nucleoplasm] (R-HSA-4754226)	0.639	7
UniProt:Q9Y3T9 NOC2L	1	NOC2L [nucleoplasm] (R-HSA-3222129)	0.632	8
UniProt:Q96FW1 OTUB1	2	OTUB1 [cytosol] (R-HSA-933411) OTUB1 [nucleoplasm] (R-HSA-6783242)	0.632	8
UniProt:P23396 RPS3	2	RPS3 [nucleoplasm] (R-HSA-6798714) RPS3 [cytosol] (R-HSA-72369)	0.632	4
UniProt:P49757 NUMB	1	NUMB [plasma membrane] (R-HSA-443595)	0.632	5
UniProt:P04019 VE6			0.623	2
UniProt:Q6PCD5 RFWD3			0.623	5
UniProt:P35232 PHB	2	PHB [cytosol] (R-HSA-5672944) PHB [mitochondrial inner membrane] (R-HSA-8953720)	0.619	6
UniProt:Q86TM6 SYVN1	1	SYVN1(1-617) [endoplasmic reticulum membrane] (R-HSA-535496)	0.61	5
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.609	2
UniProt:O14920 IKBKB	3	IKBKB [cytosol] (R-HSA-168114) p-S177,S181-IKBKB [cytosol] (R-HSA-202506) IKBKB Q432Pfs*62 [cytosol] (R-HSA-9628518)	0.609	2
UniProt:O75925 PIAS1	1	PIAS1 [nucleoplasm] (R-HSA-877307)	0.609	4
UniProt:Q9BWC9 CC106			0.608	3
UniProt:Q05655 PRKCD	12	PRKCD(330-676) [extracellular region] (R-HSA-6806199) PRKCD(1-676) [nucleoplasm] (R-HSA-450606) PRKCD(1-329) [extracellular region] (R-HSA-6806226) PRKCD(1-329) [azurophil granule lumen] (R-HSA-6799219) PRKCD(330-676) [azurophil granule lumen] (R-HSA-6799221) PRKCD(330-676) [cytosol] (R-HSA-212551) PRKCD(1-329) [cytosol] (R-HSA-212547) p-T507-PRKCD [cytosol] (R-HSA-5218746) p-T507,S645,S664-PRKCD [cytosol] (R-HSA-5218734) PRKCD [cytosol] (R-HSA-58200) active p-T507,S645,S664-PRKCD [plasma membrane] (R-HSA-5607635) p-T507,S645,S664-PRKCD(1-676) [plasma membrane] (R-HSA-198294)	0.602	4
UniProt:Q9UHC7 MKRN1	2	MKRN1 [cytosol] (R-HSA-976042) p-S109-MKRN1 [cytosol] (R-HSA-8948758)	0.602	8
UniProt:P89055 P89055			0.602	6
UniProt:P15036 ETS2	2	p-T72-ETS2 [nucleoplasm] (R-HSA-3132735) ETS2 [nucleoplasm] (R-HSA-1629811)	0.602	4
UniProt:Q9UHH9 IP6K2	1	IP6K2 [nucleoplasm] (R-HSA-1015687)	0.602	4
UniProt:Q9P0U4 CXXC1	1	CXXC1 [nucleoplasm] (R-HSA-535610)	0.597	7
UniProt:Q13155 AIMP2	1	AIMP2 [cytosol] (R-HSA-379576)	0.593	6
UniProt:Q96SB4 SRPK1			0.591	3
UniProt:Q06945 SOX4	1	SOX4 [nucleoplasm] (R-HSA-5625832)	0.591	4
UniProt:Q9UBF1 MAGC2			0.591	3
UniProt:O60285 NUAK1	2	NUAK1 [nucleoplasm] (R-HSA-3222004) p-T211-NUAK1 [nucleoplasm] (R-HSA-3222011)	0.591	5
UniProt:Q8TAQ5 ZNF420	2	ZNF420 [nucleoplasm] (R-HSA-1247509) p-S68-ZNF420 [nucleoplasm] (R-HSA-6799095)	0.591	4
UniProt:P61978 HNRNPK	2	SUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532) HNRNPK [nucleoplasm] (R-HSA-71945)	0.589	2
UniProt:Q9H3D4 TP63	1	TP63 [nucleoplasm] (R-HSA-2997585)	0.589	5
UniProt:P08047 SP1	1	SP1 [nucleoplasm] (R-HSA-1592223)	0.589	6
UniProt:Q96ST3 SIN3A	2	SIN3A [nucleoplasm] (R-HSA-351657) SUMO1-SIN3A [nucleoplasm] (R-HSA-4086071)	0.589	2
UniProt:P34931 HSPA1L	2	HSPA1L [nucleoplasm] (R-HSA-5082367) HSPA1L [cytosol] (R-HSA-3371410)	0.589	2
UniProt:O14980 XPO1	2	XPO1 [cytosol] (R-HSA-165539) XPO1 [nucleoplasm] (R-HSA-165529)	0.589	3
UniProt:O43524 FOXO3	9	p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) FOXO3 [nucleoplasm] (R-HSA-199305) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413) Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) FOXO3 [cytosol] (R-HSA-5687032)	0.589	2
UniProt:P22736 NR4A1	2	NR4A1 [nucleoplasm] (R-HSA-199831) p-S351-NR4A1 [nucleoplasm] (R-HSA-199846)	0.581	6
UniProt:Q96GM8 TOE1			0.577	3
UniProt:P61289 PSME3	2	PSME3 [cytosol] (R-HSA-68816) PSME3 [nucleoplasm] (R-HSA-174310)	0.576	7
UniProt:O43847 NRDC			0.576	6
UniProt:Q16363 LAMA4	1	LAMA4 [extracellular region] (R-HSA-2328105)	0.573	2
UniProt:P11274 BCR	4	BCR-FGFR1 fusion [cytosol] (R-HSA-1604524) BCR [cytosol] (R-HSA-195200) pY177-BCR-p-FGFR1 fusion [cytosol] (R-HSA-1839041) BCR-p-FGFR1 fusion [cytosol] (R-HSA-1838979)	0.573	2
UniProt:O75928 PIAS2	1	PIAS2 [nucleoplasm] (R-HSA-2993787)	0.573	2
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.564	2
UniProt:P10415 BCL2	1	BCL2 [mitochondrial outer membrane] (R-HSA-50757)	0.564	5
UniProt:P06748-1 NPM1			0.564	3
UniProt:Q9H7Z6 KAT8	1	KAT8 [nucleoplasm] (R-HSA-3321802)	0.564	2
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.564	2
UniProt:P25208 NFYB	1	NFYB [nucleoplasm] (R-HSA-381067)	0.564	6
UniProt:P19338 NCL	1	NCL [nucleoplasm] (R-HSA-6791213)	0.558	2
IntAct:EBI-16429055 CCSB ISOFORM ID			0.556	3
UniProt:P46821 MAP1B			0.556	6
UniProt:Q15424 SAFB	3	SUMO2,3-K231,K294-SAFB [nucleoplasm] (R-HSA-4085357) SAFB [nucleoplasm] (R-HSA-4085379) SUMO1-K231,K294-SAFB [nucleoplasm] (R-HSA-4085343)	0.556	5
UniProt:P17676 CEBPB	3	p-T235-CEBPB [nucleoplasm] (R-HSA-3857343) p-T235, S321-CEBPB [nucleoplasm] (R-HSA-3857339) CEBPB [nucleoplasm] (R-HSA-381378)	0.556	4
UniProt:Q96M61 MAGBI			0.553	2
UniProt:P04183 TK1	1	TK1 [cytosol] (R-HSA-73500)	0.553	2
UniProt:P48643 CCT5	1	CCT5 [cytosol] (R-HSA-390447)	0.547	2
UniProt:P55060 XPO2			0.544	5
UniProt:Q8R5A0	1	SMYD2 [nucleoplasm] (R-MMU-3222233)	0.544	3
UniProt:O60936 NOL3			0.544	3
UniProt:Q9PST7 Q9PST7			0.544	3
UniProt:P04731 MT1A	1	MT1A [cytosol] (R-HSA-5660412)	0.544	3
UniProt:Q9H9J4-2 USP42			0.544	2
UniProt:P38398 BRCA1	5	SUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) SUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) p-S988,S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-5683800) BRCA1 [nucleoplasm] (R-HSA-50949) p-S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-75234)	0.544	2
UniProt:P29066	5	ARRB1 [Golgi membrane] (R-RNO-350831) ARRB1 [cytoplasmic vesicle membrane] (R-RNO-351187) ARRB1 [lysosomal membrane] (R-RNO-432701) PolyUb-ARRB1 [cytosol] (R-RNO-6783186) ARRB1 [cytosol] (R-RNO-264470)	0.544	3
UniProt:P11473 VDR	2	VDR [nucleoplasm] (R-HSA-375512) SUMO2-VDR [nucleoplasm] (R-HSA-4546376)	0.537	6
UniProt:P23511 NFYA	1	NFYA [nucleoplasm] (R-HSA-420841)	0.537	11
UniProt:O15047 SETD1A	1	SETD1A [nucleoplasm] (R-HSA-3239027)	0.532	4
UniProt:P27958-PRO_0000037566			0.528	2
UniProt:Q8N3Y1 FBXW8	1	FBXW8 [cytosol] (R-HSA-976017)	0.527	2
UniProt:O75147 OBSL1	1	OBSL1 [cytosol] (R-HSA-8955929)	0.527	2
IntAct:EBI-1550792 TP53I3			0.527	3
UniProt:Q9UPR3 SMG5	1	SMG5 [cytosol] (R-HSA-927867)	0.527	2
IntAct:EBI-6620336 CD44			0.525	2
UniProt:O95863 SNAI1	1	SNAI1 [nucleoplasm] (R-HSA-2980903)	0.524	2
UniProt:P26687 Twist1	2	TWIST1 [nucleoplasm] (R-MMU-445442) Twist1 [nucleoplasm] (R-MMU-9007846)	0.524	4
UniProt:Q96PU4 UHRF2	1	UHRF2 [nucleoplasm] (R-HSA-976050)	0.524	3
UniProt:Q8IZD2 KMT2E	1	KMT2E [nucleoplasm] (R-HSA-1183225)	0.524	4
UniProt:Q08619 IFI5B			0.524	2
UniProt:O95352-2 ATG7			0.524	4
UniProt:Q7Z6Z7 HUWE1	4	HUWE1 [extracellular region] (R-HSA-6806466) HUWE1 [secretory granule lumen] (R-HSA-6801481) HUWE1 [ficolin-1-rich granule lumen] (R-HSA-6801467) HUWE1 [cytosol] (R-HSA-975983)	0.524	3
UniProt:Q92841 DDX17	2	SUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104) DDX17 [nucleoplasm] (R-HSA-3900090)	0.524	3
UniProt:P36873-1 PPP1CC			0.524	2
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.524	4
UniProt:Q03701 CEBPZ			0.524	2
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.524	3
UniProt:Q12772 SREBF2	5	SREBF2(1-1141) [Golgi membrane] (R-HSA-1655747) SREBF2(1-1141) [endoplasmic reticulum membrane] (R-HSA-1655733) SREBF2(1-522) [Golgi membrane] (R-HSA-1655752) <