Ubiquitination of phosphorylated Cdc25A

Stable Identifier
R-HSA-69598
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'ubiquitin', and 1 molecule of 'phospho-Cdc25A' are present. At the end of this reaction, 1 molecule of 'Ubiquitinated Phospho-Cdc25A' is present.

This reaction takes place in the 'cytosol' and is mediated by the 'ubiquitin-protein ligase activity' of 'Ubiquitin ligase' (Bernardi et al. 2000).

Literature References
PubMed ID Title Journal Year
10828887 Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation

Bernardi, R, Liebermann, DA, Hoffman, B

Oncogene 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ubiquitin-protein transferase activity of Ubiquitin ligase [cytosol]
Physical Entity
Activity
Created