Reactome: A Curated Pathway Database

D-fructose 6-phosphate <=> alpha-D-Glucose 6-phosphate

Stable Identifier
R-HSA-70475
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Summation

The reversible isomerization of fructose-6-phosphate to form glucose-6-phosphate is catalyzed by cytosolic phosphoglucose isomerase (Noltman 1972; Xu and Beutler 1994; Tsuboi et al. 1958).

Literature References
PubMed ID Title Journal Year
13538944 Enzymes of the human erythrocyte. IV. Phosphoglucose isomerase, purification and properties. J Biol Chem 1958
7989588 The characterization of gene mutations for human glucose phosphate isomerase deficiency associated with chronic hemolytic anemia J Clin Invest 1994
  The Enzymes, 3rd ed   1972
Participants
input
output
Participant Of
hasEvent
This entity is regulated by:
Title Physical Entity Activity
glucose-6-phosphate isomerase activity of GPI dimer [cytosol] GPI dimer [cytosol] glucose-6-phosphate isomerase activity (0004347)
Orthologous Events
 
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