Reactome: A Curated Pathway Database

D-fructose 1,6-bisphosphate + H2O => D-fructose 6-phosphate + orthophosphate

Stable Identifier
R-HSA-70479
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cytosolic fructose-1,6-bisphosphatase catalyzes the physiologically irreversible hydrolysis of fructose-1,6-bisphosphate to form fructose-6-phosphate and orthophosphate. In the body, two isoforms of the enzyme are expressed, one ubiquitous and one muscle-specific (Kikawa et al. 1997; Tillmann and Eschrich 1998).

Literature References
Participants
Participant Of
hasEvent
This entity is regulated by:
Title Physical Entity Activity
fructose 1,6-bisphosphate 1-phosphatase activity of FBP tetramer [cytosol] FBP tetramer [cytosol] fructose 1,6-bisphosphate 1-phosphatase activity (0042132)
Orthologous Events