ornithine => putrescine + CO2

Stable Identifier
R-HSA-70692
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
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ornithine => putrescine + CO2
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

L-ornithine is converted into putrescine by ODC holoenzyme complex.Putrescine is subsequent used for polyamine synthesis.

Literature References
PubMed ID Title Journal Year
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Scriver, CR, Beaudet, AL, Valle, D, Sly, WS

  2001
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
ornithine decarboxylase activity of PXLP-K69-ODC1 [cytosol]
Physical Entity
PXLP-K69-ODC1 [cytosol]
Activity
ornithine decarboxylase activity (0004586)
Orthologous Events
ornithine => putrescine + CO2 (Bos taurus)
ornithine => putrescine + CO2 (Caenorhabditis elegans)
ornithine => putrescine + CO2 (Canis familiaris)
ornithine => putrescine + CO2 (Danio rerio)
ornithine => putrescine + CO2 (Dictyostelium discoideum)
ornithine => putrescine + CO2 (Drosophila melanogaster)
ornithine => putrescine + CO2 (Mus musculus)
ornithine => putrescine + CO2 (Plasmodium falciparum)
ornithine => putrescine + CO2 (Rattus norvegicus)
ornithine => putrescine + CO2 (Saccharomyces cerevisiae)
ornithine => putrescine + CO2 (Schizosaccharomyces pombe)
ornithine => putrescine + CO2 (Sus scrofa)
ornithine => putrescine + CO2 (Xenopus tropicalis)
Cross References
Rhea
Authored
Gopinathrao, G  (2008-05-21)
Reviewed
D'Eustachio, P  (2008-06-12)