beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA

Stable Identifier
R-HSA-70881
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Mitochondrial 3-hydroxyisobutyryl-CoA hydrolase (HIBCH) catalyzes the hydrolysis of beta-hydroxyisobutyryl-CoA to form beta-hydroxyisobutyrate (3-hydroxy-2-methylpropanoate) and CoA (Hawes et al. 1996).

Literature References
PubMed ID Title Journal Year
8824301 Primary structure and tissue-specific expression of human beta-hydroxyisobutyryl-coenzyme A hydrolase.

Hawes, JW, Jaskiewicz, J, Shimomura, Y, Huang, B, Bunting, J, Harper, ET, Harris, RA

J Biol Chem 1996
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
3-hydroxyisobutyryl-CoA hydrolase activity of HIBCH [mitochondrial matrix]
Physical Entity
Activity
Orthologous Events