Reactome | HAL [cytosol]

HAL [cytosol]

Stable Identifier

R-HSA-70897

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Histidine ammonia-lyase , Histidase

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P42357 HAL

Gene Names

HAL, HIS

Chain

chain:1-657

Reference Genes

BioGPS Gene:3034 HAL

COSMIC (genes):HAL HAL

CTD Gene:3034 HAL

dbSNP Gene:3034 HAL

ENSEMBL:ENSG00000084110 HAL

HGNC:4806 HAL

KEGG:hsa:3034 HAL

Monarch:3034 HAL

NCBI Gene:3034 HAL

OMIM:609457 HAL

UCSC:P42357 HAL

Reference Transcript

Other Identifiers

11735177_at

11751231_a_at

11752202_a_at

16768792

206643_PM_at

206643_at

217521_PM_at

217521_at

3034

3466688

3466689

3466691

3466692

3466693

3466694

3466695

3466696

3466697

3466698

3466699

3466700

3466701

3466702

3466703

3466704

3466705

3466706

3466707

3466709

3466710

3466711

3466712

3466713

3466714

3466715

3466716

3466717

3466719

3466720

3466721

3466725

3466727

3466728

3466729

3466731

40735_at

56900_r_at

56905_at

7965606

A_23_P61637

D16626_at

GE62366

GO:0003824

GO:0004397

GO:0005737

GO:0005829

GO:0006520

GO:0006547

GO:0006548

GO:0016829

GO:0016841

GO:0019556

GO:0019557

HMNXSV003037022

Hs.276590.0.A1_3p_at

ILMN_1719988

ILMN_2074748

PH_hs_0022912

TC12001842.hg

g4809282_3p_at

Inferred To

haly-1 [cytosol] (Caenorhabditis elegans)

hal.2 [cytosol] (Xenopus tropicalis)

HAL [cytosol] (Bos taurus)

HAL [cytosol] (Canis familiaris)

HAL [cytosol] (Gallus gallus)

HAL [cytosol] (Sus scrofa)

Hal [cytosol] (Mus musculus)

Hal [cytosol] (Rattus norvegicus)

hal [cytosol] (Danio rerio)

hal [cytosol] (Dictyostelium discoideum)

Cross References

OpenTargets

ENSG00000084110

ENSEMBL

ENSG00000084110, ENST00000261208, ENSP00000446364, ENSP00000261208, ENST00000538703, ENSP00000440861, ENST00000541929

IntEnz

4.3.1.3

HPA

ENSG00000084110-HAL

GeneCards

HAL

ZINC - Substances

HUTH_HUMAN

ZINC target

P42357

PRO

P42357

Pharos - Targets

P42357

Orphanet

HAL

GlyGen

P42357

HMDB Protein

HMDBP00683

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.527	2
UniProt:Q9Y324 FCF1	1	FCF1 [nucleoplasm] (R-HSA-6790672)	0.527	2
UniProt:Q13616 CUL1	3	CUL1 [cytosol] (R-HSA-174230) CUL1 [nucleoplasm] (R-HSA-187551) G76-NEDD8-K720-CUL1 [cytosol] (R-HSA-8952519)	0.527	2
UniProt:Q7L190 DPPA4	1	DPPA4 [nucleoplasm] (R-HSA-452999)	0.527	3
UniProt:P57076 CF298			0.527	2
UniProt:Q9NP90 RAB9B	7	RAB9B [transport vesicle] (R-HSA-6814621) RAB9B [trans-Golgi network membrane] (R-HSA-6814620) GGC-RAB9B [trans-Golgi network membrane] (R-HSA-8876089) GGC-RAB9B [cytosol] (R-HSA-8874076) RAB9B [cytosol] (R-HSA-6813907) RAB9B [plasma membrane] (R-HSA-6804810) RAB9B [secretory granule membrane] (R-HSA-6804773)	0.527	2
UniProt:Q2M243 CCD27			0.527	2
UniProt:Q15696 ZRSR2	1	ZRSR2 [nucleoplasm] (R-HSA-8865914)	0.527	2
UniProt:Q96BY6 DOCK10	1	DOCK10 [cytosol] (R-HSA-1012998)	0.527	2
UniProt:Q9HB20 PLEKHA3	1	PLEKHA3 [Golgi membrane] (R-HSA-8870513)	0.527	2
UniProt:P02794 FTH1	5	FTH1 [cytosol] (R-HSA-434212) FTH1 [ficolin-1-rich granule lumen] (R-HSA-6801531) FTH1 [extracellular region] (R-HSA-2187212) FTH1 [tertiary granule lumen] (R-HSA-6801508) FTH1 [endocytic vesicle lumen] (R-HSA-2299670)	0.527	2
UniProt:Q68DU8 KCD16			0.527	2
UniProt:O43309 ZSC12			0.527	2
UniProt:Q96IK5 GMCL1			0.527	2
UniProt:Q14330 GPR18	1	GPR18 [plasma membrane] (R-HSA-517529)	0.527	2
UniProt:Q9NU19 TB22B			0.527	2
UniProt:Q96MH2 HEXI2			0.527	2

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