Fumarate + H2O <=> (S)-Malate

Stable Identifier
R-HSA-70982
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Mitochondrial fumarate hydratase catalyzes the reversible reaction of fumarate and water to form malate, the seventh step of the TCA cycle (Bourgeron et al. 1994). Unpublished crystallographic data indicate that the protein is a tetramer (PDB 3E04).

Literature References
Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
fumarate hydratase activity of FH tetramer [mitochondrial matrix]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea