D-methylmalonyl-CoA <=> L-methylmalonyl-CoA

Stable Identifier
R-HSA-71020
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the beginning of this reaction, 1 molecule of 'D-methylmalonyl-CoA' is present. At the end of this reaction, 1 molecule of 'L-methylmalonyl-CoA' is present.

This reaction takes place in the 'mitochondrial matrix' and is mediated by the 'methylmalonyl-CoA epimerase activity' of 'methylmalonyl-CoA epimerase'.

Literature References
PubMed ID Title Journal Year
11481338 Identification of the human methylmalonyl-CoA racemase gene based on the analysis of prokaryotic gene arrangements. Implications for decoding the human genome.

Bobik, TA, Rasche, ME

J Biol Chem 2001
  The Metabolic and Molecular Bases of Inherited Disease, 8th ed

Scriver, CR, Beaudet, AL, Valle, D, Sly, WS

  2001
13934211 Metabolism of propionic acid in animal tissues. IX. Methylmalonyl coenzyme A racemase

Mazumder, R, Sasakawa, T, Kaziro, Y, Ochoa, S

J Biol Chem 1962
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
methylmalonyl-CoA epimerase activity of MCEE [mitochondrial matrix]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea